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Protein
Submitted name:

Dynamin-1-like protein

Gene

DNM1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Dynamin-1-like proteinImported
Gene namesi
Name:DNM1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:2973. DNM1L.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087470.

PTM / Processingi

Proteomic databases

MaxQBiF8VZ52.
PeptideAtlasiF8VZ52.
PRIDEiF8VZ52.

Expressioni

Gene expression databases

BgeeiENSG00000087470.
ExpressionAtlasiF8VZ52. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8VZ52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 261Dynamin-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST240

Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119213.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR030556. DNM1L.
IPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PTHR11566:SF39. PTHR11566:SF39. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF00350. Dynamin_N. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F8VZ52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL
60 70 80 90 100
LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL
110 120 130 140 150
YTDFDEIRQE IENETERISG NNKVPVGDQP KDIELQIREL ILRFISNPNS
160 170 180 190 200
IILAVTAANT DMATSEALKI SREVDPDGRR TLAVITKLDL MDAGTDAMDV
210 220 230 240 250
LMGRVIPVKL GIIGVVNRSQ LDINNKKSVT DSIRDEYAFL QKKYPSLANR
260
NGTKYLARTL N
Length:261
Mass (Da):28,988
Last modified:September 21, 2011 - v1
Checksum:i86C54A3FDB4BE0FF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei261Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084824 Genomic DNA. No translation available.
AC087588 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000548750; ENSP00000447788; ENSG00000087470.
UCSCiuc058mpd.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084824 Genomic DNA. No translation available.
AC087588 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF8VZ52.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8VZ52.
PeptideAtlasiF8VZ52.
PRIDEiF8VZ52.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000548750; ENSP00000447788; ENSG00000087470.
UCSCiuc058mpd.1. human.

Organism-specific databases

HGNCiHGNC:2973. DNM1L.
OpenTargetsiENSG00000087470.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119213.

Miscellaneous databases

ChiTaRSiDNM1L. human.

Gene expression databases

BgeeiENSG00000087470.
ExpressionAtlasiF8VZ52. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR030556. DNM1L.
IPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PTHR11566:SF39. PTHR11566:SF39. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF00350. Dynamin_N. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8VZ52_HUMAN
AccessioniPrimary (citable) accession number: F8VZ52
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 30, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.