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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2 N

Gene

UBE2N

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiF8VZ29.

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2 NImported
Gene namesi
Name:UBE2NImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:12492. UBE2N.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000177889.

PTM / Processingi

Proteomic databases

MaxQBiF8VZ29.
PaxDbiF8VZ29.
PeptideAtlasiF8VZ29.
PRIDEiF8VZ29.

Expressioni

Gene expression databases

BgeeiENSG00000177889.
ExpressionAtlasiF8VZ29. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000316176.

Structurei

3D structure databases

ProteinModelPortaliF8VZ29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 69UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
GeneTreeiENSGT00540000070023.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F8VZ29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLPRRIIK ETQRLLAEPV PGIKAEPDES NARYFHVVIA GPQDSPFEGG
60 70 80
TFKLELFLPE EYPMAAPKIS GPQHCRSAQF CYRSRPC
Length:87
Mass (Da):9,744
Last modified:September 21, 2011 - v1
Checksum:i3013B423A3EAD174
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025260 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000549490; ENSP00000447009; ENSG00000177889.
UCSCiuc058rsw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025260 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF8VZ29.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000316176.

Proteomic databases

MaxQBiF8VZ29.
PaxDbiF8VZ29.
PeptideAtlasiF8VZ29.
PRIDEiF8VZ29.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000549490; ENSP00000447009; ENSG00000177889.
UCSCiuc058rsw.1. human.

Organism-specific databases

HGNCiHGNC:12492. UBE2N.
OpenTargetsiENSG00000177889.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
GeneTreeiENSGT00540000070023.

Enzyme and pathway databases

SignaLinkiF8VZ29.

Miscellaneous databases

ChiTaRSiUBE2N. human.

Gene expression databases

BgeeiENSG00000177889.
ExpressionAtlasiF8VZ29. baseline and differential.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF8VZ29_HUMAN
AccessioniPrimary (citable) accession number: F8VZ29
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: March 15, 2017
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.