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Protein
Submitted name:

SWI/SNF complex subunit SMARCC2

Gene

SMARCC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SWI/SNF complex subunit SMARCC2Imported
Gene namesi
Name:SMARCC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:11105. SMARCC2.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

EPDiF8VXC8.
PaxDbiF8VXC8.
PRIDEiF8VXC8.

Expressioni

Gene expression databases

BgeeiENSG00000139613.
ExpressionAtlasiF8VXC8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000267064.

Structurei

3D structure databases

ProteinModelPortaliF8VXC8.
SMRiF8VXC8. Positions 430-514, 620-685.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini424 – 52198SWIRMInterPro annotationAdd
BLAST
Domaini627 – 67852SANTInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains SWIRM domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
GeneTreeiENSGT00390000018166.
OMAiPNVKYFE.
OrthoDBiEOG091G06AJ.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000953. Chromo/shadow_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR030092. SMARCC2(BAF170).
IPR032451. SMARCC_C.
IPR032450. SMARCC_N.
IPR007526. SWIRM.
IPR032448. SWIRM-assoc.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR12802:SF38. PTHR12802:SF38. 2 hits.
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
PF16496. SWIRM-assoc_2. 1 hit.
PF16498. SWIRM-assoc_3. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52113. SSF52113. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VXC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRKKDGGP NVKYYEAADT VTQFDNVRLW LGKNYKKYIQ AEPPTNKSLS
60 70 80 90 100
SLVVQLLQFQ EEVFGKHVSN APLTKLPIKC FLDFKAGGSL CHILAAAYKF
110 120 130 140 150
KSDQGWRRYD FQNPSRMDRN VEMFMTIEKS LVQNNCLSRP NIFLCPEIEP
160 170 180 190 200
KLLGKLKDII KRHQGTVTED KNNASHVVYP VPGNLEEEEW VRPVMKRDKQ
210 220 230 240 250
VLLHWGYYPD SYDTWIPASE IEASVEDAPT PEKPRKVHAK WILDTDTFNE
260 270 280 290 300
WMNEEDYEVN DDKNPVSRRK KISAKTLTDE VNSPDSDRRD KKGGNYKKRK
310 320 330 340 350
RSPSPSPTPE AKKKNAKKGP STPYTKSKRG HREEEQEDLT KDMDEPSPVP
360 370 380 390 400
NVEEVTLPKT VNTKKDSESA PVKGGTMTDL DEQEDESMET TGKDEDENST
410 420 430 440 450
GNKGEQTKNP DLHEDNVTEQ THHIIIPSYA AWFDYNSVHA IERRALPEFF
460 470 480 490 500
NGKNKSKTPE IYLAYRNFMI DTYRLNPQEY LTSTACRRNL AGDVCAIMRV
510 520 530 540 550
HAFLEQWGLI NYQVDAESRP TPMGPPPTSH FHVLADTPSG LVPLQPKTPQ
560 570 580 590 600
GRQVDADTKA GRKGKELDDL VPETAKGKPE LQTSASQQML NFPDKGKEKP
610 620 630 640 650
TDMQNFGLRT DMYTKKNVPS KSKAAASATR EWTEQETLLL LEALEMYKDD
660 670 680 690 700
WNKVSEHVGS RTQDECILHF LRLPIEDPYL EDSEASLGPL AYQPIPFSQS
710 720 730 740 750
GNPVMSTVAF LASVVDPRVA SAAAKSALEE FSKMKEEVPT ALVEAHVRKV
760 770 780 790 800
EEAAKVTGKA DPAFGLESSG IAGTTSDEPE RIEESGNDEA RVEGQATDEK
810 820 830 840 850
KEPKEPREGG GAIEEEAKEK TSEAPKKDEE KGKEGDSEKE SEKSDGDPIV
860 870 880 890 900
DPEKEKEPKE GQEEVLKEVV ESEGERKTKV ERDIGEGNLS TAAAAALAAA
910 920 930 940 950
AVKAKHLAAV EERKIKSLVA LLVETQMKKL EIKLRHFEEL ETIMDREREA
960 970 980 990 1000
LEYQRQQLLA DRQAFHMEQL KYAEMRARQQ HFQQMHQQQQ QPPPALPPGS
1010 1020 1030 1040 1050
QPIPPTGAAG PPAVHGLAVA PASVVPAPAG SGAPPGSLGP SEQIGQAGST
1060 1070 1080 1090 1100
AGPQQQQPAG APQPGAVPPG VPPPGPHGPS PFPNQQTPPS MMPGAVPGSG
1110 1120 1130 1140 1150
HPGVAGNAPL GLPFGMPPPP PPPAPSIIPF GSLADSISIN LPAPPNLHGH
1160 1170 1180 1190 1200
HHHLPFAPGT LPPPNLPVSM ANPLHPNLPA TTTMPSSLPL GPGLGSAAAQ
1210 1220 1230 1240
SPAIVAAVQG NLLPSASPLP DPGTPLPPDP TAPSPGTVTP VPPPQ
Length:1,245
Mass (Da):136,184
Last modified:September 21, 2011 - v1
Checksum:iFEEF5643D15E712C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073896 Genomic DNA. No translation available.
RefSeqiXP_005269158.1. XM_005269101.1.
UniGeneiHs.236030.
Hs.632717.

Genome annotation databases

EnsembliENST00000550164; ENSP00000449396; ENSG00000139613.
GeneIDi6601.
UCSCiuc058pjl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073896 Genomic DNA. No translation available.
RefSeqiXP_005269158.1. XM_005269101.1.
UniGeneiHs.236030.
Hs.632717.

3D structure databases

ProteinModelPortaliF8VXC8.
SMRiF8VXC8. Positions 430-514, 620-685.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000267064.

Proteomic databases

EPDiF8VXC8.
PaxDbiF8VXC8.
PRIDEiF8VXC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000550164; ENSP00000449396; ENSG00000139613.
GeneIDi6601.
UCSCiuc058pjl.1. human.

Organism-specific databases

CTDi6601.
HGNCiHGNC:11105. SMARCC2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
GeneTreeiENSGT00390000018166.
OMAiPNVKYFE.
OrthoDBiEOG091G06AJ.

Miscellaneous databases

ChiTaRSiSMARCC2. human.
GenomeRNAii6601.

Gene expression databases

BgeeiENSG00000139613.
ExpressionAtlasiF8VXC8. baseline and differential.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000953. Chromo/shadow_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR030092. SMARCC2(BAF170).
IPR032451. SMARCC_C.
IPR032450. SMARCC_N.
IPR007526. SWIRM.
IPR032448. SWIRM-assoc.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR12802:SF38. PTHR12802:SF38. 2 hits.
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
PF16496. SWIRM-assoc_2. 1 hit.
PF16498. SWIRM-assoc_3. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52113. SSF52113. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8VXC8_HUMAN
AccessioniPrimary (citable) accession number: F8VXC8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.