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Protein
Submitted name:

Transcription factor IIIB 90 kDa subunit

Gene

BRF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. zinc ion binding Source: InterPro

GO - Biological processi

  1. regulation of mRNA stability Source: Ensembl
  2. regulation of transcription, DNA-templated Source: InterPro
  3. transcription initiation from RNA polymerase III promoter Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor IIIB 90 kDa subunitImported
Gene namesi
Name:BRF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:11551. BRF1.

Subcellular locationi

GO - Cellular componenti

  1. transcription factor TFIIIB complex Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF8VWT8.
ExpressionAtlasiF8VWT8. baseline.

Structurei

3D structure databases

ProteinModelPortaliF8VWT8.
SMRiF8VWT8. Positions 2-73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010349.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR029529. Brf1.
IPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR013150. TFIIB_cyclin.
[Graphical view]
PANTHERiPTHR11618. PTHR11618. 1 hit.
PTHR11618:SF4. PTHR11618:SF4. 1 hit.
PfamiPF00382. TFIIB. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Fragment.

F8VWT8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTALRLLQRM KRDWMHTGRR PSGLCGAALL VAARMHDFRR TVKEVISVVK
60 70 80 90 100
VCESTLRKRL TEFEDTPTSQ LTIDEFMKID LEEECDPPSY TAGQRKLRMK
110 120 130 140 150
QLEQVLSKKL EEVEGEISSY QDAIEIELEN SRPKAKGGLA SLAKDGSTED

TASSL
Length:155
Mass (Da):17,502
Last modified:September 21, 2011 - v1
Checksum:i0693DAADB2EDFBF3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei155 – 1551Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512355 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000552127; ENSP00000449788; ENSG00000185024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL512355 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF8VWT8.
SMRiF8VWT8. Positions 2-73.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000552127; ENSP00000449788; ENSG00000185024.

Organism-specific databases

HGNCiHGNC:11551. BRF1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000010349.

Miscellaneous databases

ChiTaRSiBRF1. human.
NextBioi35511954.

Gene expression databases

BgeeiF8VWT8.
ExpressionAtlasiF8VWT8. baseline.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR029529. Brf1.
IPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR013150. TFIIB_cyclin.
[Graphical view]
PANTHERiPTHR11618. PTHR11618. 1 hit.
PTHR11618:SF4. PTHR11618:SF4. 1 hit.
PfamiPF00382. TFIIB. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF8VWT8_HUMAN
AccessioniPrimary (citable) accession number: F8VWT8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: January 7, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.