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Protein
Submitted name:

Suppressor of cytokine-signaling 2

Gene

SOCS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiF8VU91.

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine-signaling 2Imported
Gene namesi
Name:SOCS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:19382. SOCS2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120833.

PTM / Processingi

Proteomic databases

PaxDbiF8VU91.
PeptideAtlasiF8VU91.
PRIDEiF8VU91.

Expressioni

Gene expression databases

BgeeiENSG00000120833.
ExpressionAtlasiF8VU91. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000339428.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 129SH2InterPro annotationAdd BLAST82

Phylogenomic databases

eggNOGiKOG4566. Eukaryota.
ENOG4111V4J. LUCA.
GeneTreeiENSGT00760000119136.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR028410. SOCS2.
[Graphical view]
PANTHERiPTHR24369:SF75. PTHR24369:SF75. 1 hit.
PfamiPF00017. SH2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F8VU91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW
60 70 80 90 100
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ
110 120 130 140
DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EA
Length:142
Mass (Da):15,731
Last modified:October 5, 2016 - v8
Checksum:i4B113020AE7E7944
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012085 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000548091; ENSP00000447902; ENSG00000120833.
UCSCiuc058rtj.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012085 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000339428.

Proteomic databases

PaxDbiF8VU91.
PeptideAtlasiF8VU91.
PRIDEiF8VU91.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000548091; ENSP00000447902; ENSG00000120833.
UCSCiuc058rtj.1. human.

Organism-specific databases

HGNCiHGNC:19382. SOCS2.
OpenTargetsiENSG00000120833.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4566. Eukaryota.
ENOG4111V4J. LUCA.
GeneTreeiENSGT00760000119136.

Enzyme and pathway databases

SignaLinkiF8VU91.

Miscellaneous databases

ChiTaRSiSOCS2. human.

Gene expression databases

BgeeiENSG00000120833.
ExpressionAtlasiF8VU91. baseline and differential.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR028410. SOCS2.
[Graphical view]
PANTHERiPTHR24369:SF75. PTHR24369:SF75. 1 hit.
PfamiPF00017. SH2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8VU91_HUMAN
AccessioniPrimary (citable) accession number: F8VU91
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: October 5, 2016
Last modified: November 2, 2016
This is version 44 of the entry and version 8 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.