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Protein
Submitted name:

TGF-beta receptor type-1

Gene

TGFBR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
TGF-beta receptor type-1Imported
Gene namesi
Name:TGFBR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000106799.12
HGNCiHGNC:11772 TGFBR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei61 – 82HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000106799

PTM / Processingi

Proteomic databases

MaxQBiF8VRH6
PeptideAtlasiF8VRH6
PRIDEiF8VRH6

Expressioni

Gene expression databases

BgeeiENSG00000106799
ExpressionAtlasiF8VRH6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8VRH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 40Activin_recpInterPro annotationAdd BLAST40

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2052 Eukaryota
ENOG410XQT0 LUCA
GeneTreeiENSGT00760000118876

Family and domain databases

InterProiView protein in InterPro
IPR000472 Activin_recp
IPR000333 TGFB_receptor
PANTHERiPTHR23255 PTHR23255, 1 hit
PfamiView protein in Pfam
PF01064 Activin_recp, 1 hit

Sequencei

Sequence statusi: Fragment.

F8VRH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIAEIDLIP RDRPFVCAPS SKTGSVTTTY CCNQDHCNKI ELPTTGPFSV
60 70 80 90 100
KSSPGLGPVE LAAVIAGPVC FVCISLMLMV YICHNRTVIH HRVPNEEDPS
110
LDRPFISEGT TLKD
Length:114
Mass (Da):12,418
Last modified:September 21, 2011 - v1
Checksum:i96CA6C3E845C4179
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei114Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162427 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000548365; ENSP00000448518; ENSG00000106799
UCSCiuc064utp.1 human

Similar proteinsi

Entry informationi

Entry nameiF8VRH6_HUMAN
AccessioniPrimary (citable) accession number: F8VRH6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 23, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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