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F8VQM8

- F8VQM8_MOUSE

UniProt

F8VQM8 - F8VQM8_MOUSE

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Protein
Submitted name:

Short transient receptor potential channel 2

Gene

Trpc2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calmodulin binding Source: MGI
  2. damaged DNA binding Source: InterPro
  3. diacylglycerol binding Source: MGI
  4. store-operated calcium channel activity Source: MGI

GO - Biological processi

  1. acrosome reaction Source: MGI
  2. calcium ion transport Source: MGI
  3. female courtship behavior Source: MGI
  4. inter-male aggressive behavior Source: MGI
  5. mating behavior, sex discrimination Source: MGI
  6. negative regulation of male mating behavior Source: MGI
  7. positive regulation of cytosolic calcium ion concentration Source: MGI
  8. regulation of gene expression Source: MGI
  9. response to pheromone Source: MGI
  10. single strand break repair Source: InterPro
  11. territorial aggressive behavior Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Short transient receptor potential channel 2Imported
Gene namesi
Name:Trpc2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:109527. Trpc2.

Subcellular locationi

GO - Cellular componenti

  1. dendrite membrane Source: MGI
  2. endomembrane system Source: MGI
  3. endoplasmic reticulum membrane Source: MGI
  4. Golgi membrane Source: MGI
  5. integral component of membrane Source: UniProtKB-KW
  6. nuclear envelope Source: MGI
  7. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119180.
OMAiRKDLGNR.
TreeFamiTF313147.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.60.120.260. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR008979. Galactose-bd-like.
IPR005821. Ion_trans_dom.
IPR013555. TRP_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
IPR002706. Xrcc1_N.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
PF01834. XRCC1_N. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01643. TRPCHANNEL2.
SMARTiSM00248. ANK. 2 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49785. SSF49785. 1 hit.

Sequencei

Sequence statusi: Complete.

F8VQM8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPVKISHVV SFSSQDPKYP VENLLNPDSH RGPWLSCPQD KTGQLKVEFQ
60 70 80 90 100
LERAVPISYI DVGNCGCAFL QIDVGRSSWP LDRPFVTLLP ATMLMSRTDS
110 120 130 140 150
KSGKNRSGVR MFKDGDFLTP ASGESWDRLR LTCSQPFTRH QSFGLAFLRV
160 170 180 190 200
RSSLGSLADP VVDPSAPGSS GLNQNSTDVL ESDPRPWLTN PSIRRTFFPD
210 220 230 240 250
PQTSTKEISE LKGMLKQLQP GPLGRAARMV LSAARKAPPA SVVSPNNSHG
260 270 280 290 300
EPGPSRAESA EPRAEEPNRK TAVGRRKRRK VQEPRRSLSN SSSQPNRRTG
310 320 330 340 350
RTRQRQHRPQ TKSDDGGVQA AGQCPICAGF FSIETLPQHA ATCGESPPPQ
360 370 380 390 400
PASPASLSSS ESVLRRHHVA LTPVPLVPKP QPNWTEIVNK KLKFPPTLLR
410 420 430 440 450
AIQEGQLGLV QQLLESSSDA SGAGPGGPLR NVEESEDRSW REALNLAIRL
460 470 480 490 500
GHEVITDVLL ANVKFDFRQI HEALLVAVDT NQPAVVRRLL ARLEREKGRK
510 520 530 540 550
VDTKSFSLAF FDSSIDGSRF APGVTPLTLA CQKDLYEIAQ LLMDQGHTIA
560 570 580 590 600
RPHPVSCACL ECSNARRYDL LKFSLSRINT YRGIASRAHL SLASEDAMLA
610 620 630 640 650
AFQLSRELRR LARKEPEFKP QYIALESLCQ DYGFELLGMC RNQSEVTAVL
660 670 680 690 700
NDLGEDSETE PEAEGLGQAF EEGIPNLARL RLAVNYNQKQ FVAHPICQQV
710 720 730 740 750
LSSIWCGNLA GWRGSTTIWK LFVAFLIFLT MPFLCIGYWL APKSQLGRLL
760 770 780 790 800
KIPVLKFLLH SASYLWFLIF LLGESLVMET QLSTFKGRSQ SVWETSLHMI
810 820 830 840 850
WVTGFLWFEC KEVWIEGLRS YLLDWWNFLD VVILSLYLAS FALRLLLAGL
860 870 880 890 900
AYMHCRDASD STTCRYFTTA ERSEWRTEDP QFLAEVLFAV TSMLSFTRLA
910 920 930 940 950
YILPAHESLG TLQISIGKMI DDMIRFMFIL MIILTAFLCG LNNIYVPYQE
960 970 980 990 1000
SEKLGNFNET FQFLFWTMFG MEEHTVVDMP QFLVPEFVGR AMYGIFTIVM
1010 1020 1030 1040 1050
VIVLLNMLIA MITNSFQKIE DDADVEWKFA RSKLYLSYFR EGLTLPVPFN
1060 1070 1080 1090 1100
ILPSPKAAFY LVRRIFRFLC CGSSCCKAKK SDYPPIGTFT NPGARAGSAG
1110 1120 1130 1140 1150
EGERVSYRLR VIKALVQRYI ETARREFEET RRKDLGNRLT ELTKTVSRLQ
1160 1170 1180 1190 1200
SEVASVQKNL AAGGAPRPPD GASILSRYIT RVRNSFQNLG PPTSDTPAEL
1210 1220 1230 1240 1250
TMPGIVETEV SLGDGLDGTG EAGAPAPGEP GSSSSAHVLV HREQEAEGSG
1260
DLLLEGDLET KGES
Length:1,264
Mass (Da):140,722
Last modified:September 21, 2011 - v1
Checksum:i7980E6ED0FD79F73
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132297 Genomic DNA. No translation available.
AC150275 Genomic DNA. No translation available.
RefSeqiNP_035774.2. NM_011644.3.
UniGeneiMm.292904.

Genome annotation databases

EnsembliENSMUST00000084843; ENSMUSP00000081903; ENSMUSG00000070425.
ENSMUST00000094129; ENSMUSP00000091679; ENSMUSG00000070425.
GeneIDi102443351.
KEGGimmu:102443351.
UCSCiuc009iql.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132297 Genomic DNA. No translation available.
AC150275 Genomic DNA. No translation available.
RefSeqi NP_035774.2. NM_011644.3.
UniGenei Mm.292904.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 22064.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000084843 ; ENSMUSP00000081903 ; ENSMUSG00000070425 .
ENSMUST00000094129 ; ENSMUSP00000091679 ; ENSMUSG00000070425 .
GeneIDi 102443351.
KEGGi mmu:102443351.
UCSCi uc009iql.1. mouse.

Organism-specific databases

CTDi 102443351.
MGIi MGI:109527. Trpc2.

Phylogenomic databases

GeneTreei ENSGT00760000119180.
OMAi RKDLGNR.
TreeFami TF313147.

Miscellaneous databases

NextBioi 301876.
SOURCEi Search...

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
2.60.120.260. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR008979. Galactose-bd-like.
IPR005821. Ion_trans_dom.
IPR013555. TRP_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
IPR002706. Xrcc1_N.
[Graphical view ]
PANTHERi PTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
Pfami PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
PF01834. XRCC1_N. 1 hit.
[Graphical view ]
PRINTSi PR01097. TRNSRECEPTRP.
PR01643. TRPCHANNEL2.
SMARTi SM00248. ANK. 2 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
SSF49785. SSF49785. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8VQM8_MOUSE
AccessioniPrimary (citable) accession number: F8VQM8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3