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F8VQM8

- F8VQM8_MOUSE

UniProt

F8VQM8 - F8VQM8_MOUSE

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Protein
Submitted name:

Short transient receptor potential channel 2

Gene
Trpc2
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. calmodulin binding Source: MGI
  2. damaged DNA binding Source: InterPro
  3. diacylglycerol binding Source: MGI
  4. protein binding Source: MGI
  5. store-operated calcium channel activity Source: MGI

GO - Biological processi

  1. acrosome reaction Source: MGI
  2. calcium ion transport Source: MGI
  3. female courtship behavior Source: MGI
  4. inter-male aggressive behavior Source: MGI
  5. mating behavior, sex discrimination Source: MGI
  6. negative regulation of male mating behavior Source: MGI
  7. positive regulation of cytosolic calcium ion concentration Source: MGI
  8. regulation of gene expression Source: MGI
  9. response to pheromone Source: MGI
  10. single strand break repair Source: InterPro
  11. territorial aggressive behavior Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Short transient receptor potential channel 2Imported
Gene namesi
Name:Trpc2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:109527. Trpc2.

Subcellular locationi

GO - Cellular componenti

  1. dendrite membrane Source: MGI
  2. endomembrane system Source: MGI
  3. endoplasmic reticulum membrane Source: MGI
  4. Golgi membrane Source: MGI
  5. integral component of membrane Source: UniProtKB-KW
  6. nuclear envelope Source: MGI
  7. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

ANK repeatSAAS annotations, TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00680000099764.
OMAiRKDLGNR.
TreeFamiTF313147.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.60.120.260. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR008979. Galactose-bd-like.
IPR005821. Ion_trans_dom.
IPR013555. TRP_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
IPR002706. Xrcc1_N.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
PF01834. XRCC1_N. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01643. TRPCHANNEL2.
SMARTiSM00248. ANK. 2 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49785. SSF49785. 1 hit.

Sequencei

Sequence statusi: Complete.

F8VQM8-1 [UniParc]FASTAAdd to Basket

« Hide

MAPVKISHVV SFSSQDPKYP VENLLNPDSH RGPWLSCPQD KTGQLKVEFQ     50
LERAVPISYI DVGNCGCAFL QIDVGRSSWP LDRPFVTLLP ATMLMSRTDS 100
KSGKNRSGVR MFKDGDFLTP ASGESWDRLR LTCSQPFTRH QSFGLAFLRV 150
RSSLGSLADP VVDPSAPGSS GLNQNSTDVL ESDPRPWLTN PSIRRTFFPD 200
PQTSTKEISE LKGMLKQLQP GPLGRAARMV LSAARKAPPA SVVSPNNSHG 250
EPGPSRAESA EPRAEEPNRK TAVGRRKRRK VQEPRRSLSN SSSQPNRRTG 300
RTRQRQHRPQ TKSDDGGVQA AGQCPICAGF FSIETLPQHA ATCGESPPPQ 350
PASPASLSSS ESVLRRHHVA LTPVPLVPKP QPNWTEIVNK KLKFPPTLLR 400
AIQEGQLGLV QQLLESSSDA SGAGPGGPLR NVEESEDRSW REALNLAIRL 450
GHEVITDVLL ANVKFDFRQI HEALLVAVDT NQPAVVRRLL ARLEREKGRK 500
VDTKSFSLAF FDSSIDGSRF APGVTPLTLA CQKDLYEIAQ LLMDQGHTIA 550
RPHPVSCACL ECSNARRYDL LKFSLSRINT YRGIASRAHL SLASEDAMLA 600
AFQLSRELRR LARKEPEFKP QYIALESLCQ DYGFELLGMC RNQSEVTAVL 650
NDLGEDSETE PEAEGLGQAF EEGIPNLARL RLAVNYNQKQ FVAHPICQQV 700
LSSIWCGNLA GWRGSTTIWK LFVAFLIFLT MPFLCIGYWL APKSQLGRLL 750
KIPVLKFLLH SASYLWFLIF LLGESLVMET QLSTFKGRSQ SVWETSLHMI 800
WVTGFLWFEC KEVWIEGLRS YLLDWWNFLD VVILSLYLAS FALRLLLAGL 850
AYMHCRDASD STTCRYFTTA ERSEWRTEDP QFLAEVLFAV TSMLSFTRLA 900
YILPAHESLG TLQISIGKMI DDMIRFMFIL MIILTAFLCG LNNIYVPYQE 950
SEKLGNFNET FQFLFWTMFG MEEHTVVDMP QFLVPEFVGR AMYGIFTIVM 1000
VIVLLNMLIA MITNSFQKIE DDADVEWKFA RSKLYLSYFR EGLTLPVPFN 1050
ILPSPKAAFY LVRRIFRFLC CGSSCCKAKK SDYPPIGTFT NPGARAGSAG 1100
EGERVSYRLR VIKALVQRYI ETARREFEET RRKDLGNRLT ELTKTVSRLQ 1150
SEVASVQKNL AAGGAPRPPD GASILSRYIT RVRNSFQNLG PPTSDTPAEL 1200
TMPGIVETEV SLGDGLDGTG EAGAPAPGEP GSSSSAHVLV HREQEAEGSG 1250
DLLLEGDLET KGES 1264
Length:1,264
Mass (Da):140,722
Last modified:September 21, 2011 - v1
Checksum:i7980E6ED0FD79F73
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132297 Genomic DNA. No translation available.
AC150275 Genomic DNA. No translation available.
RefSeqiNP_035774.2. NM_011644.3.
UniGeneiMm.292904.

Genome annotation databases

EnsembliENSMUST00000084843; ENSMUSP00000081903; ENSMUSG00000070425.
ENSMUST00000094129; ENSMUSP00000091679; ENSMUSG00000070425.
GeneIDi102443351.
KEGGimmu:102443351.
UCSCiuc009iql.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132297 Genomic DNA. No translation available.
AC150275 Genomic DNA. No translation available.
RefSeqi NP_035774.2. NM_011644.3.
UniGenei Mm.292904.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 22064.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000084843 ; ENSMUSP00000081903 ; ENSMUSG00000070425 .
ENSMUST00000094129 ; ENSMUSP00000091679 ; ENSMUSG00000070425 .
GeneIDi 102443351.
KEGGi mmu:102443351.
UCSCi uc009iql.1. mouse.

Organism-specific databases

CTDi 102443351.
MGIi MGI:109527. Trpc2.

Phylogenomic databases

GeneTreei ENSGT00680000099764.
OMAi RKDLGNR.
TreeFami TF313147.

Miscellaneous databases

NextBioi 301876.
SOURCEi Search...

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
2.60.120.260. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR008979. Galactose-bd-like.
IPR005821. Ion_trans_dom.
IPR013555. TRP_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
IPR002706. Xrcc1_N.
[Graphical view ]
PANTHERi PTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
Pfami PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
PF01834. XRCC1_N. 1 hit.
[Graphical view ]
PRINTSi PR01097. TRNSRECEPTRP.
PR01643. TRPCHANNEL2.
SMARTi SM00248. ANK. 2 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
SSF49785. SSF49785. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8VQM8_MOUSE
AccessioniPrimary (citable) accession number: F8VQM8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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