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F8VQM8 (F8VQM8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1264 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000081903 Ensembl ENSMUSP00000091679

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainANK repeat SAAS SAAS005821
Transmembrane RuleBase RU003378
   Molecular functionIon channel RuleBase RU003378
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacrosome reaction

Inferred from mutant phenotype PubMed 11331878. Source: MGI

calcium ion transport

Inferred from mutant phenotype PubMed 11331878. Source: MGI

female courtship behavior

Inferred from mutant phenotype PubMed 17676034. Source: MGI

inter-male aggressive behavior

Inferred from mutant phenotype PubMed 11823606. Source: MGI

mating behavior, sex discrimination

Inferred from mutant phenotype PubMed 11823606PubMed 11972034. Source: MGI

negative regulation of male mating behavior

Inferred from genetic interaction PubMed 24089208. Source: MGI

positive regulation of cytosolic calcium ion concentration

Inferred from physical interaction PubMed 10051594. Source: MGI

response to pheromone

Inferred from mutant phenotype PubMed 11823606PubMed 11972034PubMed 24089208. Source: MGI

single strand break repair

Inferred from electronic annotation. Source: InterPro

territorial aggressive behavior

Inferred from mutant phenotype PubMed 11972034PubMed 17676034. Source: MGI

   Cellular_componentGolgi membrane

Inferred from direct assay PubMed 10998353. Source: MGI

dendrite membrane

Inferred from mutant phenotype PubMed 14642279. Source: MGI

endomembrane system

Inferred from direct assay PubMed 10998353. Source: MGI

endoplasmic reticulum membrane

Inferred from direct assay PubMed 10998353. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

nuclear envelope

Inferred from direct assay PubMed 10998353. Source: MGI

plasma membrane

Inferred from direct assay PubMed 14699131. Source: MGI

   Molecular_functioncalmodulin binding

Inferred from direct assay PubMed 12601176. Source: MGI

damaged DNA binding

Inferred from electronic annotation. Source: InterPro

diacylglycerol binding

Inferred from mutant phenotype PubMed 14642279. Source: MGI

store-operated calcium channel activity

Inferred from direct assay PubMed 10051594. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F8VQM8 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 7980E6ED0FD79F73

FASTA1,264140,722
        10         20         30         40         50         60 
MAPVKISHVV SFSSQDPKYP VENLLNPDSH RGPWLSCPQD KTGQLKVEFQ LERAVPISYI 

        70         80         90        100        110        120 
DVGNCGCAFL QIDVGRSSWP LDRPFVTLLP ATMLMSRTDS KSGKNRSGVR MFKDGDFLTP 

       130        140        150        160        170        180 
ASGESWDRLR LTCSQPFTRH QSFGLAFLRV RSSLGSLADP VVDPSAPGSS GLNQNSTDVL 

       190        200        210        220        230        240 
ESDPRPWLTN PSIRRTFFPD PQTSTKEISE LKGMLKQLQP GPLGRAARMV LSAARKAPPA 

       250        260        270        280        290        300 
SVVSPNNSHG EPGPSRAESA EPRAEEPNRK TAVGRRKRRK VQEPRRSLSN SSSQPNRRTG 

       310        320        330        340        350        360 
RTRQRQHRPQ TKSDDGGVQA AGQCPICAGF FSIETLPQHA ATCGESPPPQ PASPASLSSS 

       370        380        390        400        410        420 
ESVLRRHHVA LTPVPLVPKP QPNWTEIVNK KLKFPPTLLR AIQEGQLGLV QQLLESSSDA 

       430        440        450        460        470        480 
SGAGPGGPLR NVEESEDRSW REALNLAIRL GHEVITDVLL ANVKFDFRQI HEALLVAVDT 

       490        500        510        520        530        540 
NQPAVVRRLL ARLEREKGRK VDTKSFSLAF FDSSIDGSRF APGVTPLTLA CQKDLYEIAQ 

       550        560        570        580        590        600 
LLMDQGHTIA RPHPVSCACL ECSNARRYDL LKFSLSRINT YRGIASRAHL SLASEDAMLA 

       610        620        630        640        650        660 
AFQLSRELRR LARKEPEFKP QYIALESLCQ DYGFELLGMC RNQSEVTAVL NDLGEDSETE 

       670        680        690        700        710        720 
PEAEGLGQAF EEGIPNLARL RLAVNYNQKQ FVAHPICQQV LSSIWCGNLA GWRGSTTIWK 

       730        740        750        760        770        780 
LFVAFLIFLT MPFLCIGYWL APKSQLGRLL KIPVLKFLLH SASYLWFLIF LLGESLVMET 

       790        800        810        820        830        840 
QLSTFKGRSQ SVWETSLHMI WVTGFLWFEC KEVWIEGLRS YLLDWWNFLD VVILSLYLAS 

       850        860        870        880        890        900 
FALRLLLAGL AYMHCRDASD STTCRYFTTA ERSEWRTEDP QFLAEVLFAV TSMLSFTRLA 

       910        920        930        940        950        960 
YILPAHESLG TLQISIGKMI DDMIRFMFIL MIILTAFLCG LNNIYVPYQE SEKLGNFNET 

       970        980        990       1000       1010       1020 
FQFLFWTMFG MEEHTVVDMP QFLVPEFVGR AMYGIFTIVM VIVLLNMLIA MITNSFQKIE 

      1030       1040       1050       1060       1070       1080 
DDADVEWKFA RSKLYLSYFR EGLTLPVPFN ILPSPKAAFY LVRRIFRFLC CGSSCCKAKK 

      1090       1100       1110       1120       1130       1140 
SDYPPIGTFT NPGARAGSAG EGERVSYRLR VIKALVQRYI ETARREFEET RRKDLGNRLT 

      1150       1160       1170       1180       1190       1200 
ELTKTVSRLQ SEVASVQKNL AAGGAPRPPD GASILSRYIT RVRNSFQNLG PPTSDTPAEL 

      1210       1220       1230       1240       1250       1260 
TMPGIVETEV SLGDGLDGTG EAGAPAPGEP GSSSSAHVLV HREQEAEGSG DLLLEGDLET 


KGES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC132297 Genomic DNA. No translation available.
AC150275 Genomic DNA. No translation available.
RefSeqNP_035774.2. NM_011644.3.
UniGeneMm.292904.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

DNASU22064.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000084843; ENSMUSP00000081903; ENSMUSG00000070425.
ENSMUST00000094129; ENSMUSP00000091679; ENSMUSG00000070425.
GeneID102443351.
UCSCuc009iql.1. mouse.

Organism-specific databases

CTD102443351.
MGIMGI:109527. Trpc2.

Phylogenomic databases

GeneTreeENSGT00680000099764.
OMARKDLGNR.
TreeFamTF313147.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
2.60.120.260. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR008979. Galactose-bd-like.
IPR005821. Ion_trans_dom.
IPR013555. TRP_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
IPR002706. Xrcc1_N.
[Graphical view]
PANTHERPTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
PfamPF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
PF01834. XRCC1_N. 1 hit.
[Graphical view]
PRINTSPR01097. TRNSRECEPTRP.
PR01643. TRPCHANNEL2.
SMARTSM00248. ANK. 2 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
SSF49785. SSF49785. 1 hit.
ProtoNetSearch...

Other

NextBio301876.
SOURCESearch...

Entry information

Entry nameF8VQM8_MOUSE
AccessionPrimary (citable) accession number: F8VQM8
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)