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Protein
Submitted name:

Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough

Gene

Xntrpc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthroughImported
Gene namesi
Name:XntrpcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:5546370 Xntrpc

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei718 – 741HelicalSequence analysisAdd BLAST24
Transmembranei753 – 772HelicalSequence analysisAdd BLAST20
Transmembranei831 – 853HelicalSequence analysisAdd BLAST23
Transmembranei924 – 945HelicalSequence analysisAdd BLAST22
Transmembranei991 – 1012HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000070425

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 149XRCC1_NInterPro annotationAdd BLAST149
Domaini557 – 619TRP_2InterPro annotationAdd BLAST63
Domaini762 – 1023Ion_transInterPro annotationAdd BLAST262

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1132 – 1159Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation

Keywords - Domaini

ANK repeatSAAS annotation, Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3609 Eukaryota
ENOG410XQ0Y LUCA
GeneTreeiENSGT00760000119180
KOiK04965
OMAiYFLDWWN
OrthoDBiEOG091G0KP0
TreeFamiTF313147

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR008979 Galactose-bd-like_sf
IPR005821 Ion_trans_dom
IPR013555 TRP_dom
IPR005458 TRPC2_channel
IPR002153 TRPC_channel
IPR002706 Xrcc1_N
PANTHERiPTHR10117 PTHR10117, 1 hit
PTHR10117:SF6 PTHR10117:SF6, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
PF08344 TRP_2, 1 hit
PF01834 XRCC1_N, 1 hit
PRINTSiPR01097 TRNSRECEPTRP
PR01643 TRPCHANNEL2
SUPFAMiSSF48403 SSF48403, 1 hit
SSF49785 SSF49785, 1 hit

Sequencei

Sequence statusi: Complete.

F8VQM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPVKISHVV SFSSQDPKYP VENLLNPDSH RGPWLSCPQD KTGQLKVEFQ
60 70 80 90 100
LERAVPISYI DVGNCGCAFL QIDVGRSSWP LDRPFVTLLP ATMLMSRTDS
110 120 130 140 150
KSGKNRSGVR MFKDGDFLTP ASGESWDRLR LTCSQPFTRH QSFGLAFLRV
160 170 180 190 200
RSSLGSLADP VVDPSAPGSS GLNQNSTDVL ESDPRPWLTN PSIRRTFFPD
210 220 230 240 250
PQTSTKEISE LKGMLKQLQP GPLGRAARMV LSAARKAPPA SVVSPNNSHG
260 270 280 290 300
EPGPSRAESA EPRAEEPNRK TAVGRRKRRK VQEPRRSLSN SSSQPNRRTG
310 320 330 340 350
RTRQRQHRPQ TKSDDGGVQA AGQCPICAGF FSIETLPQHA ATCGESPPPQ
360 370 380 390 400
PASPASLSSS ESVLRRHHVA LTPVPLVPKP QPNWTEIVNK KLKFPPTLLR
410 420 430 440 450
AIQEGQLGLV QQLLESSSDA SGAGPGGPLR NVEESEDRSW REALNLAIRL
460 470 480 490 500
GHEVITDVLL ANVKFDFRQI HEALLVAVDT NQPAVVRRLL ARLEREKGRK
510 520 530 540 550
VDTKSFSLAF FDSSIDGSRF APGVTPLTLA CQKDLYEIAQ LLMDQGHTIA
560 570 580 590 600
RPHPVSCACL ECSNARRYDL LKFSLSRINT YRGIASRAHL SLASEDAMLA
610 620 630 640 650
AFQLSRELRR LARKEPEFKP QYIALESLCQ DYGFELLGMC RNQSEVTAVL
660 670 680 690 700
NDLGEDSETE PEAEGLGQAF EEGIPNLARL RLAVNYNQKQ FVAHPICQQV
710 720 730 740 750
LSSIWCGNLA GWRGSTTIWK LFVAFLIFLT MPFLCIGYWL APKSQLGRLL
760 770 780 790 800
KIPVLKFLLH SASYLWFLIF LLGESLVMET QLSTFKGRSQ SVWETSLHMI
810 820 830 840 850
WVTGFLWFEC KEVWIEGLRS YLLDWWNFLD VVILSLYLAS FALRLLLAGL
860 870 880 890 900
AYMHCRDASD STTCRYFTTA ERSEWRTEDP QFLAEVLFAV TSMLSFTRLA
910 920 930 940 950
YILPAHESLG TLQISIGKMI DDMIRFMFIL MIILTAFLCG LNNIYVPYQE
960 970 980 990 1000
SEKLGNFNET FQFLFWTMFG MEEHTVVDMP QFLVPEFVGR AMYGIFTIVM
1010 1020 1030 1040 1050
VIVLLNMLIA MITNSFQKIE DDADVEWKFA RSKLYLSYFR EGLTLPVPFN
1060 1070 1080 1090 1100
ILPSPKAAFY LVRRIFRFLC CGSSCCKAKK SDYPPIGTFT NPGARAGSAG
1110 1120 1130 1140 1150
EGERVSYRLR VIKALVQRYI ETARREFEET RRKDLGNRLT ELTKTVSRLQ
1160 1170 1180 1190 1200
SEVASVQKNL AAGGAPRPPD GASILSRYIT RVRNSFQNLG PPTSDTPAEL
1210 1220 1230 1240 1250
TMPGIVETEV SLGDGLDGTG EAGAPAPGEP GSSSSAHVLV HREQEAEGSG
1260
DLLLEGDLET KGES
Length:1,264
Mass (Da):140,722
Last modified:September 21, 2011 - v1
Checksum:i7980E6ED0FD79F73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132297 Genomic DNA No translation available.
AC150275 Genomic DNA No translation available.
RefSeqiNP_035774.2, NM_011644.3
UniGeneiMm.292904

Genome annotation databases

EnsembliENSMUST00000084843; ENSMUSP00000081903; ENSMUSG00000070425
ENSMUST00000094129; ENSMUSP00000091679; ENSMUSG00000070425
GeneIDi102443351
KEGGimmu:102443351
UCSCiuc033jau.1 mouse

Similar proteinsi

Entry informationi

Entry nameiF8VQM8_MOUSE
AccessioniPrimary (citable) accession number: F8VQM8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 25, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health