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Protein
Submitted name:

Nuclear receptor corepressor 2

Gene

Ncor2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor corepressor 2Imported
Gene namesi
Name:Ncor2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1337080. Ncor2.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiF8VQL9.
PaxDbiF8VQL9.
PRIDEiF8VQL9.

Expressioni

Gene expression databases

BgeeiF8VQL9.
ExpressionAtlasiF8VQL9. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiF8VQL9. 1 interaction.
STRINGi10090.ENSMUSP00000083250.

Structurei

3D structure databases

ProteinModelPortaliF8VQL9.
SMRiF8VQL9. Positions 167-207, 408-476, 611-681.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini427 – 47852SANTInterPro annotationAdd
BLAST
Domaini606 – 65752SANTInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili169 – 20638Sequence analysisAdd
BLAST
Coiled coili494 – 54754Sequence analysisAdd
BLAST
Coiled coili655 – 68228Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1878. Eukaryota.
ENOG410YDXP. LUCA.
GeneTreeiENSGT00840000129748.
OMAiYRSHIPL.
TreeFamiTF106423.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR031557. N-CoR_GPS2_interact.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF15784. GPS2_interact. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VQL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARSHTDVGLL EYQHHPRDYT
60 70 80 90 100
SHLSPGSIIQ PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI
110 120 130 140 150
EFTESKRPRL ELLPDTLLRP SPLLATGQPS GSEDLTKDRS LAGKLEPVSP
160 170 180 190 200
PSPPHADPEL ELAPSRLSKE ELIQNMDRVD REITMVEQQI SKLKKKQQQL
210 220 230 240 250
EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA AHRILEGLGP
260 270 280 290 300
QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ
310 320 330 340 350
RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM
360 370 380 390 400
QSRVGQRGSG LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY
410 420 430 440 450
DADQQRIKFI NMNGLMDDPM KVYKDRQVTN MWSEQERDTF REKFMQHPKN
460 470 480 490 500
FGLIASFLER KTVAECVLYY YLTKKNENYK SLVRRSYRRR GKSQQQQQQQ
510 520 530 540 550
QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE LSKEKTDDTS
560 570 580 590 600
GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL
610 620 630 640 650
ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF
660 670 680 690 700
NYKKRQNLDE ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE
710 720 730 740 750
MEASGASANE EELAEEAEAS QASGNEVPRV GECSGPAAVN NSSDTESVPS
760 770 780 790 800
PRSEATKDTG PKPTGTEALP AATQPPVPPP EEPAVAPAEP SPVPDASGPP
810 820 830 840 850
SPEPSPSPAA PPATVDKDEQ EAPAAPAPQT EDAKEQKSEA EEIDVGKPEE
860 870 880 890 900
PEASEEPPES VKSDHKEETE EEPEDKAKGT EAIETVSEAP LKVEEAGSKA
910 920 930 940 950
AVTKGSSSGA TQDSDSSATC SADEVDEPEG GDKGRLLSPR PSLLTPAGDP
960 970 980 990 1000
RASTSPQKPL DLKQLKQRAA AIPPIVTKVH EPPREDTVPP KPVPPVPPPT
1010 1020 1030 1040 1050
QHLQPEGDVS QQSGGSPRGK SRSPVPPAEK EAEKPAFFPA FPTEGPKLPT
1060 1070 1080 1090 1100
EPPRWSSGLP FPIPPREVIK TSPHAADPSA FSYTPPGHPL PLGLHDSARP
1110 1120 1130 1140 1150
VLPRPPISNP PPLISSAKHP GVLERQLGAI SQQGMSVQLR VPHSEHAKAP
1160 1170 1180 1190 1200
MGPLTMGLPL AVDPKKLAPF SGVKQEQLSP RGQAGPPESL GVPTAQETSV
1210 1220 1230 1240 1250
LRGTALGSAT SGSITKGLPS TRAADGPSYR GSITHGTPAD VLYKGTISRI
1260 1270 1280 1290 1300
VGEDSPSRLD RAREDTLPKG HVIYEGKKGH VLSYEGGMSV SQCSKEDGRS
1310 1320 1330 1340 1350
SSGPPHETAA PKRTYDMMEG RVGRTVTSAS IEGLMGRAIP EQHSPHLKEQ
1360 1370 1380 1390 1400
HHIRGSITQG IPRSYVEAQE DYLRREAKLL KREGTPPPPP PPRDLTETYK
1410 1420 1430 1440 1450
PRPLDPLGPL KLKPTHEGVV ATVKEAGRSI HEIPREELRR TPELPLAPRP
1460 1470 1480 1490 1500
LKEGSITQGT PLKYDSGAPS TGTKKHDVRS IIGSPGRPFP ALHPLDIMAD
1510 1520 1530 1540 1550
ARALERACYE ESLKSRSGTS SGAGGSITRG APVVVPELGK PRQSPLTYED
1560 1570 1580 1590 1600
HGAPFTSHLP RGSPVTTREP TPRLQEGSLL SSKASQDRKL TSTPREIAKS
1610 1620 1630 1640 1650
PHSTVPEHHP HPISPYEHLL RGVTGVDLYR GHIPLAFDPT SIPRGIPLEA
1660 1670 1680 1690 1700
AAAAYYLPRH LAPSPTYPHL YPPYLIRGYP DTAALENRQT IINDYITSQQ
1710 1720 1730 1740 1750
MHHNAASAMA QRADMLRGLS PRESSLALNY AAGPRGIIDL SQVPHLPVLV
1760 1770 1780 1790 1800
PPTPGTPATA IDRLAYLPTA PPPFSSRHSS SPLSPGGPTH LAKPTATSSS
1810 1820 1830 1840 1850
ERERERERER DKSILTSTTT VEHAPIWRPG TEQSSGAGGS SRPASHTHQH
1860 1870 1880 1890 1900
SPISPRTQDA LQQRPSVLHN TSMKGVVTSV EPGTPTVLRW ARSTSTSSPV
1910 1920 1930 1940 1950
RPAATFPPAT HCPLGGTLEG VYPTLMEPVL LPKETSRVAR PERPRVDAGH
1960 1970 1980 1990 2000
AFLTKPPARE PASSPSKSSE PRSLAPPSSS HTAIARTPAK NLAPHHASPD
2010 2020 2030 2040 2050
PPAPTSASDL HREKTQSKPF SIQELELRSL GYHSGAGYSP DGVEPISPVS
2060 2070 2080 2090 2100
SPSLTHDKGL SKPLEELEKS HLEGELRHKQ PGPMKLSAEA AHLPHLRPLP
2110 2120 2130 2140 2150
ESQPSSSPLL QTAPGIKGHQ RVVTLAQHIS EVITQDYTRH HPQQLSGPLP
2160 2170 2180 2190 2200
APLYSFPGAS CPVLDLRRPP SDLYLPPPDH GTPARGSPHS EGGKRSPEPS
2210 2220 2230 2240 2250
KTSVLGSSED AIEPVSPPEG MTEPGHARST AYPLLYRDGE QGEPRMGSKS
2260 2270 2280 2290 2300
PGNTSQPPAF FSKLTESNSA MVKSKKQEIN KKLNTHNRNE PEYNIGQPGT
2310 2320 2330 2340 2350
EIFNMPAITG AGLMTCRSQA VQEHASTNMG LEAIIRKALM GKYDQWEEPP
2360 2370 2380 2390 2400
PLGANAFNPL NASASLPAAA MPITTADGRS DHALTSPGGG GKAKVSGRPS
2410 2420 2430 2440 2450
SRKAKSPAPG LASGDRPPSV SSVHSEGDCN RRTPLTNRVW EDRPSSAGST
2460 2470 2480 2490 2500
PFPYNPLIMR LQAGVMASPP PPGLAAGSGP LAGPHHAWDE EPKPLLCSQY

ETLSDSE
Length:2,507
Mass (Da):273,409
Last modified:September 21, 2011 - v1
Checksum:i38AAC11138EB5509
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132118 Genomic DNA. No translation available.
AC139377 Genomic DNA. No translation available.
RefSeqiXP_011239130.1. XM_011240828.1.
UniGeneiMm.278646.

Genome annotation databases

EnsembliENSMUST00000111402; ENSMUSP00000107033; ENSMUSG00000029478.
GeneIDi20602.
UCSCiuc029vor.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132118 Genomic DNA. No translation available.
AC139377 Genomic DNA. No translation available.
RefSeqiXP_011239130.1. XM_011240828.1.
UniGeneiMm.278646.

3D structure databases

ProteinModelPortaliF8VQL9.
SMRiF8VQL9. Positions 167-207, 408-476, 611-681.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF8VQL9. 1 interaction.
STRINGi10090.ENSMUSP00000083250.

Proteomic databases

MaxQBiF8VQL9.
PaxDbiF8VQL9.
PRIDEiF8VQL9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111402; ENSMUSP00000107033; ENSMUSG00000029478.
GeneIDi20602.
UCSCiuc029vor.1. mouse.

Organism-specific databases

CTDi9612.
MGIiMGI:1337080. Ncor2.

Phylogenomic databases

eggNOGiKOG1878. Eukaryota.
ENOG410YDXP. LUCA.
GeneTreeiENSGT00840000129748.
OMAiYRSHIPL.
TreeFamiTF106423.

Miscellaneous databases

ChiTaRSiNcor2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiF8VQL9.
ExpressionAtlasiF8VQL9. baseline and differential.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR031557. N-CoR_GPS2_interact.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF15784. GPS2_interact. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  6. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF8VQL9_MOUSE
AccessioniPrimary (citable) accession number: F8VQL9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 8, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.