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Protein

POU domain protein

Gene

Pou2f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pou2f1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:101898. Pou2f1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiF8VQL7.
PaxDbiF8VQL7.
PeptideAtlasiF8VQL7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000026565.
ExpressionAtlasiF8VQL7. baseline and differential.
GenevisibleiF8VQL7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124738.

Structurei

3D structure databases

ProteinModelPortaliF8VQL7.
SMRiF8VQL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini293 – 367POU-specificInterPro annotationAdd BLAST75
Domaini392 – 452Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VQL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDCSDCVLD SRMNNPSETN KSSMESEDAS TGTQTNGLDF QKQPVPVGGA
60 70 80 90 100
ISTAQAQAFL GHLHQVQLAG TSLQAAAQSL NVQSKSSEES GDSQQSSQPS
110 120 130 140 150
SQPPSVQSAI PQTQLMLAGG QITGLTLTPA QQQLLLQQAQ AQAQLLAAAV
160 170 180 190 200
QQHSASQQHS AAGATISASA ATPMTQIPLS QPIQIAQDLQ QLQQLQQQNL
210 220 230 240 250
NLQQFVLVHP TTNLQPAQFI ISQTPQGQQG LLQAQNLLTQ LPQQSQANLL
260 270 280 290 300
QPQPSITLTS QPTTPTRTIA AASVQTLPQS QSTPKRIDTP SLEEPSDLEE
310 320 330 340 350
LEQFAKTFKQ RRIKLGFTQG DVGLAMGKLY GNDFSQTTIS RFEALNLSFK
360 370 380 390 400
NMCKLKPLLE KWLNDAENLS SDSTASSPSA LNSPGLGAEG LNRRRKKRTS
410 420 430 440 450
IETNIRVALE KSFMENQKPT SEDITLIAEQ LNMEKEVIRV WFCNRRQKEK
460 470 480 490 500
RINPPSSGGT SSSPIKAIFP SPASLVATTP SLVTSSTATT LTVNPVLPLT
510 520 530 540 550
SAAVTNLSLT DQDLRRGCSW EVLRSLPDRV TTTAGTTDST SNNNTATVIS
560 570 580 590 600
TAPPASSAVT SPSLSPSPSA SASTSEASSA SETNTTQTTS TPLPSPLGAS
610 620 630 640 650
QVMVTTPGLQ TAAAALQGAA QLPANASLAA MAAAAGLSPG LMAPSQFAAG
660 670 680 690 700
GALLSLSPGT LGSALSPALM SNSTLATIQA LASSGSLPIT SLDATGNLVF
710 720 730 740 750
ANAGGAPNIV TAPLFLNPQN LSLLTSNPVS LVSAAAASTG NSAPTASLHA
760 770 780
SSTSTESIQS SLFTVASASG PASTTTAASK AQ
Length:782
Mass (Da):80,885
Last modified:September 21, 2011 - v1
Checksum:i006E1499AB276590
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093371 Genomic DNA. No translation available.
RefSeqiNP_945152.2. NM_198934.3.
UniGeneiMm.245261.

Genome annotation databases

EnsembliENSMUST00000111427; ENSMUSP00000107056; ENSMUSG00000026565.
GeneIDi18986.
UCSCiuc007djw.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093371 Genomic DNA. No translation available.
RefSeqiNP_945152.2. NM_198934.3.
UniGeneiMm.245261.

3D structure databases

ProteinModelPortaliF8VQL7.
SMRiF8VQL7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124738.

Proteomic databases

MaxQBiF8VQL7.
PaxDbiF8VQL7.
PeptideAtlasiF8VQL7.

Protocols and materials databases

DNASUi18986.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111427; ENSMUSP00000107056; ENSMUSG00000026565.
GeneIDi18986.
UCSCiuc007djw.2. mouse.

Organism-specific databases

CTDi5451.
MGIiMGI:101898. Pou2f1.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.

Miscellaneous databases

ChiTaRSiPou2f1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026565.
ExpressionAtlasiF8VQL7. baseline and differential.
GenevisibleiF8VQL7. MM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8VQL7_MOUSE
AccessioniPrimary (citable) accession number: F8VQL7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 30, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.