Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Laminin subunit gamma-1

Gene

Lamc1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-3000157. Laminin interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
Laminin subunit gamma-1Imported
Gene namesi
Name:Lamc1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:99914. Lamc1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence analysisAdd
BLAST
Chaini34 – 16071574Sequence analysisPRO_5003379251Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiF8VQJ3.
PaxDbiF8VQJ3.

Expressioni

Gene expression databases

BgeeiF8VQJ3.
ExpressionAtlasiF8VQJ3. baseline and differential.
GenevisibleiF8VQJ3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027752.

Structurei

3D structure databases

ProteinModelPortaliF8VQJ3.
SMRiF8VQJ3. Positions 37-395, 771-932.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 283240Laminin N-terminalInterPro annotationAdd
BLAST
Domaini284 – 33956Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini340 – 39556Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini396 – 44247Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini443 – 49250Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini519 – 687169Laminin IV type AInterPro annotationAdd
BLAST
Domaini722 – 77049Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini771 – 82555Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini826 – 88156Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini882 – 93251Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini933 – 98048Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini981 – 102848Laminin EGF-likeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili1066 – 109328Sequence analysisAdd
BLAST
Coiled coili1129 – 115628Sequence analysisAdd
BLAST
Coiled coili1220 – 126142Sequence analysisAdd
BLAST
Coiled coili1277 – 132549Sequence analysisAdd
BLAST
Coiled coili1452 – 148635Sequence analysisAdd
BLAST
Coiled coili1494 – 152128Sequence analysisAdd
BLAST
Coiled coili1533 – 159058Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, Laminin EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1836. Eukaryota.
ENOG410XRDC. LUCA.
GeneTreeiENSGT00780000121851.
KOiK05635.
OMAiLCACNGH.
OrthoDBiEOG7SR4KJ.
TreeFamiTF352481.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR000742. EGF-like_dom.
IPR008979. Galactose-bd-like.
IPR002049. Laminin_EGF.
IPR000034. Laminin_IV.
IPR008211. Laminin_N.
[Graphical view]
PfamiPF00052. Laminin_B. 1 hit.
PF00053. Laminin_EGF. 11 hits.
PF00055. Laminin_N. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 9 hits.
SM00180. EGF_Lam. 10 hits.
SM00281. LamB. 1 hit.
SM00136. LamNT. 1 hit.
[Graphical view]
PROSITEiPS01248. EGF_LAM_1. 11 hits.
PS50027. EGF_LAM_2. 10 hits.
PS51115. LAMININ_IVA. 1 hit.
PS51117. LAMININ_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VQJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGGGRAALA LQPRGRLWPL LAVLAAVAGC VRAAMDECAD EGGRPQRCMP
60 70 80 90 100
EFVNAAFNVT VVATNTCGTP PEEYCVQTGV TGVTKSCHLC DAGQQHLQHG
110 120 130 140 150
AAFLTDYNNQ ADTTWWQSQT MLAGVQYPNS INLTLHLGKA FDITYVRLKF
160 170 180 190 200
HTSRPESFAI YKRTREDGPW IPYQYYSGSC ENTYSKANRG FIRTGGDEQQ
210 220 230 240 250
ALCTDEFSDI SPLTGGNVAF STLEGRPSAY NFDNSPVLQE WVTATDIRVT
260 270 280 290 300
LNRLNTFGDE VFNDPKVLKS YYYAISDFAV GGRCKCNGHA SECVKNEFDK
310 320 330 340 350
LMCNCKHNTY GVDCEKCLPF FNDRPWRRAT AESASECLPC DCNGRSQECY
360 370 380 390 400
FDPELYRSTG HGGHCTNCRD NTDGAKCERC RENFFRLGNT EACSPCHCSP
410 420 430 440 450
VGSLSTQCDS YGRCSCKPGV MGDKCDRCQP GFHSLTEAGC RPCSCDPSGS
460 470 480 490 500
TDECNVETGR CVCKDNVEGF NCERCKPGFF NLESSNPKGC TPCFCFGHSS
510 520 530 540 550
VCTNAVGYSV YDISSTFQID EDGWRVEQRD GSEASLEWSS DRQDIAVISD
560 570 580 590 600
SYFPRYFIAP VKFLGNQVLS YGQNLSFSFR VDRRDTRLSA EDLVLEGAGL
610 620 630 640 650
RVSVPLIAQG NSYPSETTVK YIFRLHEATD YPWRPALSPF EFQKLLNNLT
660 670 680 690 700
SIKIRGTYSE RSAGYLDDVT LQSARPGPGV PATWVESCTC PVGYGGQFCE
710 720 730 740 750
TCLPGYRRET PSLGPYSPCV LCTCNGHSET CDPETGVCDC RDNTAGPHCE
760 770 780 790 800
KCSDGYYGDS TLGTSSDCQP CPCPGGSSCA IVPKTKEVVC THCPTGTAGK
810 820 830 840 850
RCELCDDGYF GDPLGSNGPV RLCRPCQCND NIDPNAVGNC NRLTGECLKC
860 870 880 890 900
IYNTAGFYCD RCKEGFFGNP LAPNPADKCK ACACNPYGTV QQQSSCNPVT
910 920 930 940 950
GQCQCLPHVS GRDCGTCDPG YYNLQSGQGC ERCDCHALGS TNGQCDIRTG
960 970 980 990 1000
QCECQPGITG QHCERCETNH FGFGPEGCKP CDCHHEGSLS LQCKEDGRCE
1010 1020 1030 1040 1050
CREGFVGNRC DQCEENYFYN RSWPGCQECP ACYRLVKDKV AEHRVKLQEL
1060 1070 1080 1090 1100
ESLIANLGTG DDMVTDQAFE DRLKEAEREV TDLLREAQEV KDVDQNLMDR
1110 1120 1130 1140 1150
LQRVNSSLHS QISRLQNIRN TIEETGILAE RARSRVESTE QLIEIASREL
1160 1170 1180 1190 1200
EKAKMAAANV SITQPESTGE PNNMTLLAEE ARKLAERHKQ EADDIVRVAK
1210 1220 1230 1240 1250
TANETSAEAY NLLLRTLAGE NQTALEIEEL NRKYEQAKNI SQDLEKQAAR
1260 1270 1280 1290 1300
VHEEAKRAGD KAVEIYASVA QLTPVDSEAL ENEANKIKKE AADLDRLIDQ
1310 1320 1330 1340 1350
KLKDYEDLRE DMRGKEHEVK NLLEKGKAEQ QTADQLLARA DAAKALAEEA
1360 1370 1380 1390 1400
AKKGRSTLQE ANDILNNLKD FDRRVNDNKT AAEEALRRIP AINRTIAEAN
1410 1420 1430 1440 1450
EKTREAQLAL GNAAADATEA KNKAHEAERI ASAVQKNATS TKADAERTFG
1460 1470 1480 1490 1500
EVTDLDNEVN GMLRQLEEAE NELKKKQDDA DQDMMMAGMA SQAAQEAELN
1510 1520 1530 1540 1550
ARKAKNSVSS LLSQLNNLLD QLGQLDTVDL NKLNEIEGSL NKAKDEMKAS
1560 1570 1580 1590 1600
DLDRKVSDLE SEARKQEAAI MDYNRDIAEI IKDIHNLEDI KKTLPTGCFN

TPSIEKP
Length:1,607
Mass (Da):177,187
Last modified:September 21, 2011 - v1
Checksum:i535B8D64E4CB3967
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117550 Genomic DNA. No translation available.
AC159966 Genomic DNA. No translation available.
RefSeqiNP_034813.2. NM_010683.2.
UniGeneiMm.1249.

Genome annotation databases

EnsembliENSMUST00000027752; ENSMUSP00000027752; ENSMUSG00000026478.
GeneIDi226519.
KEGGimmu:226519.
UCSCiuc007czu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117550 Genomic DNA. No translation available.
AC159966 Genomic DNA. No translation available.
RefSeqiNP_034813.2. NM_010683.2.
UniGeneiMm.1249.

3D structure databases

ProteinModelPortaliF8VQJ3.
SMRiF8VQJ3. Positions 37-395, 771-932.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027752.

Proteomic databases

MaxQBiF8VQJ3.
PaxDbiF8VQJ3.

Protocols and materials databases

DNASUi226519.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000027752; ENSMUSP00000027752; ENSMUSG00000026478.
GeneIDi226519.
KEGGimmu:226519.
UCSCiuc007czu.1. mouse.

Organism-specific databases

CTDi3915.
MGIiMGI:99914. Lamc1.

Phylogenomic databases

eggNOGiKOG1836. Eukaryota.
ENOG410XRDC. LUCA.
GeneTreeiENSGT00780000121851.
KOiK05635.
OMAiLCACNGH.
OrthoDBiEOG7SR4KJ.
TreeFamiTF352481.

Enzyme and pathway databases

ReactomeiR-MMU-3000157. Laminin interactions.

Miscellaneous databases

ChiTaRSiLamc1. mouse.
NextBioi378200.
SOURCEiSearch...

Gene expression databases

BgeeiF8VQJ3.
ExpressionAtlasiF8VQJ3. baseline and differential.
GenevisibleiF8VQJ3. MM.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR000742. EGF-like_dom.
IPR008979. Galactose-bd-like.
IPR002049. Laminin_EGF.
IPR000034. Laminin_IV.
IPR008211. Laminin_N.
[Graphical view]
PfamiPF00052. Laminin_B. 1 hit.
PF00053. Laminin_EGF. 11 hits.
PF00055. Laminin_N. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 9 hits.
SM00180. EGF_Lam. 10 hits.
SM00281. LamB. 1 hit.
SM00136. LamNT. 1 hit.
[Graphical view]
PROSITEiPS01248. EGF_LAM_1. 11 hits.
PS50027. EGF_LAM_2. 10 hits.
PS51115. LAMININ_IVA. 1 hit.
PS51117. LAMININ_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8VQJ3_MOUSE
AccessioniPrimary (citable) accession number: F8VQJ3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 11, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.