Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Gene

Agap3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3Imported
Gene namesi
Name:Agap3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2183446. Agap3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiF8VQE9.
PeptideAtlasiF8VQE9.
PRIDEiF8VQE9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000023353.
ExpressionAtlasiF8VQE9. baseline and differential.
GenevisibleiF8VQE9. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024123.

Structurei

3D structure databases

ProteinModelPortaliF8VQE9.
SMRiF8VQE9. Positions 125-288, 400-498, 592-644, 664-877.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini402 – 640239PHInterPro annotationAdd
BLAST
Domaini788 – 87790ANK_REP_REGIONInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains Arf-GAP domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG0705. Eukaryota.
COG5347. LUCA.
GeneTreeiENSGT00760000118874.
OMAiDQWSEAA.
OrthoDBiEOG091G123A.
TreeFamiTF317762.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.30.29.30. 2 hits.
3.40.50.300. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR027417. P-loop_NTPase.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF50729. SSF50729. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS51421. RAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VQE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFQAGGGQS PQQQQSLAAP GTGGGGGGGA GGGGQFGGAG PGAGGGGPSQ
60 70 80 90 100
QLAGGPPQQF ALSNSAAIRA EIQRFESVHP NIYAIYDLIE RIEDLALQNQ
110 120 130 140 150
IREHVISIED SFVNSQEWTL SRSVPELKVG IVGNLSSGKS ALVHRYLTGT
160 170 180 190 200
YVQEESPEGG RFKKEIVVDG QSYLLLIRDE GGPPELQFAA WVDAVVFVFS
210 220 230 240 250
LEDEISFQTV YNYFLRLCSF RNASEVPMVL VGTQDAISAA NPRVIDDSRA
260 270 280 290 300
RKLSTDLKRC TYYETCATYG LNVERVFQDV AQKVVALRKK QQLAIGPCKS
310 320 330 340 350
LPNSPSHSAV SAASIPAVHI NQATNGGSSA FSDYSSSVPS TPSISQRELR
360 370 380 390 400
IETIAASSTP TPIRKQSKRR SNIFTSRKGA DLDREKKAAE CRVDSIGSGR
410 420 430 440 450
AIPIKQGILL KRSGKSLNKE WKKKYVTLCD NGLLTYHPSL HDYMQNIHGK
460 470 480 490 500
EIDLLRTTVK VPGKRLPRAT PTTAPGTSPR ANGLAMERSN TQLGGATGAP
510 520 530 540 550
HSASSTSLHS ERPHSSAWAG SRPGPEGLHQ RSCSVSSTDQ WSEAAALPAS
560 570 580 590 600
MQHPASGPAE SLSSSPKLEP PPSPHSNRKK HRGKKSTGTP RPDGPSSAAE
610 620 630 640 650
EAEESFEFVV VSLTGQTWHF EASTAEEREL WVQSVQAQIL ASLQGCRSAK
660 670 680 690 700
DKTRLGNQNT ALAVQAVRTV RGNSLCIDCE APNPDWASLN LGALMCIECS
710 720 730 740 750
GIHRHLGAHL SRVRSLDLDD WPPELLAVMT AMGNALANSV WEGALDGYSK
760 770 780 790 800
PGPEACREEK ERWIRAKYEQ KLFLAPLPSS DVPLGQQLLR AVVEDDLRLL
810 820 830 840 850
VMLLAHGSKE EVNETYGDGD GRTALHLSSA MANVVFTQLL IWYGVDVRSR
860 870 880 890 900
DARGLTPLAY ARRAGSQECA DILIQHGCPG EGCGLAPTPN REPANGTNPS
910
AELHRSPSIL
Length:910
Mass (Da):97,695
Last modified:September 21, 2011 - v1
Checksum:i9062E9155468DE5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120353 Genomic DNA. No translation available.
RefSeqiNP_631892.2. NM_139153.2.
UniGeneiMm.250703.

Genome annotation databases

EnsembliENSMUST00000024123; ENSMUSP00000024123; ENSMUSG00000023353.
GeneIDi213990.
UCSCiuc008wrv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120353 Genomic DNA. No translation available.
RefSeqiNP_631892.2. NM_139153.2.
UniGeneiMm.250703.

3D structure databases

ProteinModelPortaliF8VQE9.
SMRiF8VQE9. Positions 125-288, 400-498, 592-644, 664-877.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024123.

Proteomic databases

PaxDbiF8VQE9.
PeptideAtlasiF8VQE9.
PRIDEiF8VQE9.

Protocols and materials databases

DNASUi213990.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000024123; ENSMUSP00000024123; ENSMUSG00000023353.
GeneIDi213990.
UCSCiuc008wrv.1. mouse.

Organism-specific databases

CTDi116988.
MGIiMGI:2183446. Agap3.

Phylogenomic databases

eggNOGiKOG0705. Eukaryota.
COG5347. LUCA.
GeneTreeiENSGT00760000118874.
OMAiDQWSEAA.
OrthoDBiEOG091G123A.
TreeFamiTF317762.

Miscellaneous databases

ChiTaRSiAgap3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000023353.
ExpressionAtlasiF8VQE9. baseline and differential.
GenevisibleiF8VQE9. MM.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.30.29.30. 2 hits.
3.40.50.300. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR027417. P-loop_NTPase.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF50729. SSF50729. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS51421. RAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8VQE9_MOUSE
AccessioniPrimary (citable) accession number: F8VQE9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 7, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.