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Protein
Submitted name:

Kinesin-like protein KIF21B

Gene

Kif21b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi87 – 94ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin-like protein KIF21BImported
Gene namesi
Name:Kif21bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:109234 Kif21b

PTM / Processingi

Proteomic databases

MaxQBiF8VQE2
PRIDEiF8VQE2

Expressioni

Gene expression databases

BgeeiENSMUSG00000041642
ExpressionAtlasiF8VQE2 baseline and differential
GenevisibleiF8VQE2 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiF8VQE2 10 interactors.

Structurei

3D structure databases

ProteinModelPortaliF8VQE2
SMRiF8VQE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 371Kinesin motorInterPro annotationAdd BLAST364
Domaini1306 – 1624WD_REPEATS_REGIONInterPro annotationAdd BLAST319
Repeati1306 – 1345WDPROSITE-ProRule annotationAdd BLAST40
Repeati1502 – 1541WDPROSITE-ProRule annotationAdd BLAST40
Repeati1543 – 1584WDPROSITE-ProRule annotationAdd BLAST42
Repeati1585 – 1617WDPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili379 – 406Sequence analysisAdd BLAST28
Coiled coili439 – 459Sequence analysisAdd BLAST21
Coiled coili472 – 506Sequence analysisAdd BLAST35
Coiled coili535 – 562Sequence analysisAdd BLAST28
Coiled coili572 – 594Sequence analysisAdd BLAST23
Coiled coili637 – 685Sequence analysisAdd BLAST49
Coiled coili701 – 773Sequence analysisAdd BLAST73
Coiled coili785 – 819Sequence analysisAdd BLAST35
Coiled coili934 – 1017Sequence analysisAdd BLAST84

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0244 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00910000143992
KOiK10395
OrthoDBiEOG091G0DUL
TreeFamiTF105224

Family and domain databases

Gene3Di2.130.10.102 hits
3.40.850.101 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR24115 PTHR24115, 2 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PF00400 WD40, 3 hits
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 4 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

F8VQE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY
60 70 80 90 100
DFVFDLDTWQ EQIYSTCVSK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG
110 120 130 140 150
FDTVTSEEEQ GIIPRAIAHL FRGIDERKRR AQEKGVTGPE FKVSAQFLEL
160 170 180 190 200
YNEEILDLFD STRDPDARHR RSNIKIHEDA NGGIYTTGVT SRLINSQEEL
210 220 230 240 250
IQCLKQGALS RTTASTQMNV QSSRSHAIFT IHLCQMRVCA QPDLVNETVT
260 270 280 290 300
GLPDGAAPTG TEYETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
310 320 330 340 350
LLALGNVISA LGDQSKKVVH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP
360 370 380 390 400
SDRDFMETLN TLKYANRARN IKNKVVVNQD KTSQQISALR AEIARLQMEL
410 420 430 440 450
MEYKAGKRVI GEDGTEGYSD LFRENAMLQK ENGALRLRVK AMQEAIDAIN
460 470 480 490 500
NRVTQLMSQE ANLLLAKAGD GNEAIGALIQ NYIREIEELR TKLLESEAMN
510 520 530 540 550
ESLRRSLSRA SARNPYSLGA SPAGPAFGGS PATSMEDASE VIRKAKQDLE
560 570 580 590 600
RLKKKEVRQR RKSPEKEAFK KRAKLQAENS EETDENEAEE EEEERDESGC
610 620 630 640 650
EEEEGREDED EDSGSEESLV DSDSDPEEKE VNFQADLADL TCEIEIKQKL
660 670 680 690 700
IDELENSQRR LQTLKHQYEE KLILLQNKIR DTQLERDRVL QNLSTMECYT
710 720 730 740 750
EEKANKIKAD YEKRLREMNR DLQKLQAAQK EHARLLKNQS RYERELKKLQ
760 770 780 790 800
AEVAEMKKAK VALMKQMREE QQRRRLVETK RNREIAQLKK EQRRQEFQIR
810 820 830 840 850
ALESQKRQQE IVLRRKTQEV SALRRLAKPM SERVAGRVGL KPPNMDSGAE
860 870 880 890 900
VSASTTSSEA ESGARSVSSI VRQWNRKIDH FLGDRPTATV NGGRPARKKF
910 920 930 940 950
QKKGASQSFS KAARLKWQSL ERRIIDIVMQ RMTIVNLEAD MERLIKKREE
960 970 980 990 1000
LFLLQEALRR KREHLQAESP EEEKGLQELA EEIEVLAANI DYINDSITDC
1010 1020 1030 1040 1050
QATIVQLEET KEELDSTDTS VVISSCSLAE ARLLLDNFLK ASIDKGLQVA
1060 1070 1080 1090 1100
QKEAQIRLLE GRLRQTDMTG SSQNHLLLDA LREKAEAHPE LQALIYNVQH
1110 1120 1130 1140 1150
ENGYASTDEE VSEFSEGSFS QSFTMKGSTS HDDFKFKGEP KLSAQMKAVS
1160 1170 1180 1190 1200
AECLGPPLDS STKNITKSLA SLVEIKEDGV GFSIRDPYYR DKVSRTVSLP
1210 1220 1230 1240 1250
TRGSTFPRQS RGATDTSPLT RRKSYDRGQP IRSTDMGFTP PSSPPTRPRN
1260 1270 1280 1290 1300
DRNVFSRLTS NQSQGSALDK SDDSDSSLSE VLRGIITPIG GAKGARTAPL
1310 1320 1330 1340 1350
QCISMAEGHT KPILCLDATD ELLFTGSKDR SCKMWNLVTG QEIAALKGHP
1360 1370 1380 1390 1400
NNVVSIKYCS HSGLVFSVSS SYIKVWDIRD SAKCIRTLTS SGQVISGDAC
1410 1420 1430 1440 1450
IATSTRAITS AQGEHQINQM ALSPSGSMLY VASGNAVRIW ELNRFQPIGK
1460 1470 1480 1490 1500
LTGHIGPVMC LTVTQTSNQH DLVVTGSKDH YVKMFQLGDC VTGTIGPTHN
1510 1520 1530 1540 1550
FEPPHYDGIE CLAIQGDILF SGSRDNGIKK WDLDQQELIQ QIPNAHKDWV
1560 1570 1580 1590 1600
CALAFVPGRP MLLSACRAGF IKVWNVDNFT PIGEIKGHDS PINAICTNSK
1610 1620
HIFTASSDLT VKFWSIRRLP AAHP
Length:1,624
Mass (Da):181,401
Last modified:September 21, 2011 - v1
Checksum:i77D2B513FC6E6DA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124550 Genomic DNA No translation available.
RefSeqiNP_001034561.1, NM_001039472.1
UniGeneiMm.276135

Genome annotation databases

EnsembliENSMUST00000075164; ENSMUSP00000074661; ENSMUSG00000041642
GeneIDi16565
KEGGimmu:16565
UCSCiuc007cul.1 mouse

Similar proteinsi

Entry informationi

Entry nameiF8VQE2_MOUSE
AccessioniPrimary (citable) accession number: F8VQE2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 25, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported