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Protein
Submitted name:

Kinesin-like protein KIF21B

Gene

Kif21b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin-like protein KIF21BImported
Gene namesi
Name:Kif21bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:109234. Kif21b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiF8VQE2.
PaxDbiF8VQE2.
PRIDEiF8VQE2.

Expressioni

Gene expression databases

BgeeiF8VQE2.
ExpressionAtlasiF8VQE2. baseline and differential.
GenevisibleiF8VQE2. MM.

Interactioni

Protein-protein interaction databases

IntActiF8VQE2. 10 interactions.
STRINGi10090.ENSMUSP00000074661.

Structurei

3D structure databases

ProteinModelPortaliF8VQE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 371364Kinesin motorInterPro annotationAdd
BLAST
Domaini1306 – 1624319WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili379 – 40628Sequence analysisAdd
BLAST
Coiled coili472 – 50635Sequence analysisAdd
BLAST
Coiled coili535 – 56228Sequence analysisAdd
BLAST
Coiled coili572 – 59423Sequence analysisAdd
BLAST
Coiled coili637 – 68549Sequence analysisAdd
BLAST
Coiled coili701 – 77373Sequence analysisAdd
BLAST
Coiled coili785 – 81935Sequence analysisAdd
BLAST
Coiled coili934 – 101784Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.SAAS annotation
Contains kinesin motor domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

eggNOGiKOG0244. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00840000129683.
KOiK10395.
OrthoDBiEOG708VZ4.
TreeFamiTF105224.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
IPR009053. Prefoldin.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 5 hits.
PfamiPF00225. Kinesin. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
SSF50978. SSF50978. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 4 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VQE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY
60 70 80 90 100
DFVFDLDTWQ EQIYSTCVSK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG
110 120 130 140 150
FDTVTSEEEQ GIIPRAIAHL FRGIDERKRR AQEKGVTGPE FKVSAQFLEL
160 170 180 190 200
YNEEILDLFD STRDPDARHR RSNIKIHEDA NGGIYTTGVT SRLINSQEEL
210 220 230 240 250
IQCLKQGALS RTTASTQMNV QSSRSHAIFT IHLCQMRVCA QPDLVNETVT
260 270 280 290 300
GLPDGAAPTG TEYETLTAKF HFVDLAGSER LKRTGATGER AKEGISINCG
310 320 330 340 350
LLALGNVISA LGDQSKKVVH VPYRDSKLTR LLQDSLGGNS QTIMIACVSP
360 370 380 390 400
SDRDFMETLN TLKYANRARN IKNKVVVNQD KTSQQISALR AEIARLQMEL
410 420 430 440 450
MEYKAGKRVI GEDGTEGYSD LFRENAMLQK ENGALRLRVK AMQEAIDAIN
460 470 480 490 500
NRVTQLMSQE ANLLLAKAGD GNEAIGALIQ NYIREIEELR TKLLESEAMN
510 520 530 540 550
ESLRRSLSRA SARNPYSLGA SPAGPAFGGS PATSMEDASE VIRKAKQDLE
560 570 580 590 600
RLKKKEVRQR RKSPEKEAFK KRAKLQAENS EETDENEAEE EEEERDESGC
610 620 630 640 650
EEEEGREDED EDSGSEESLV DSDSDPEEKE VNFQADLADL TCEIEIKQKL
660 670 680 690 700
IDELENSQRR LQTLKHQYEE KLILLQNKIR DTQLERDRVL QNLSTMECYT
710 720 730 740 750
EEKANKIKAD YEKRLREMNR DLQKLQAAQK EHARLLKNQS RYERELKKLQ
760 770 780 790 800
AEVAEMKKAK VALMKQMREE QQRRRLVETK RNREIAQLKK EQRRQEFQIR
810 820 830 840 850
ALESQKRQQE IVLRRKTQEV SALRRLAKPM SERVAGRVGL KPPNMDSGAE
860 870 880 890 900
VSASTTSSEA ESGARSVSSI VRQWNRKIDH FLGDRPTATV NGGRPARKKF
910 920 930 940 950
QKKGASQSFS KAARLKWQSL ERRIIDIVMQ RMTIVNLEAD MERLIKKREE
960 970 980 990 1000
LFLLQEALRR KREHLQAESP EEEKGLQELA EEIEVLAANI DYINDSITDC
1010 1020 1030 1040 1050
QATIVQLEET KEELDSTDTS VVISSCSLAE ARLLLDNFLK ASIDKGLQVA
1060 1070 1080 1090 1100
QKEAQIRLLE GRLRQTDMTG SSQNHLLLDA LREKAEAHPE LQALIYNVQH
1110 1120 1130 1140 1150
ENGYASTDEE VSEFSEGSFS QSFTMKGSTS HDDFKFKGEP KLSAQMKAVS
1160 1170 1180 1190 1200
AECLGPPLDS STKNITKSLA SLVEIKEDGV GFSIRDPYYR DKVSRTVSLP
1210 1220 1230 1240 1250
TRGSTFPRQS RGATDTSPLT RRKSYDRGQP IRSTDMGFTP PSSPPTRPRN
1260 1270 1280 1290 1300
DRNVFSRLTS NQSQGSALDK SDDSDSSLSE VLRGIITPIG GAKGARTAPL
1310 1320 1330 1340 1350
QCISMAEGHT KPILCLDATD ELLFTGSKDR SCKMWNLVTG QEIAALKGHP
1360 1370 1380 1390 1400
NNVVSIKYCS HSGLVFSVSS SYIKVWDIRD SAKCIRTLTS SGQVISGDAC
1410 1420 1430 1440 1450
IATSTRAITS AQGEHQINQM ALSPSGSMLY VASGNAVRIW ELNRFQPIGK
1460 1470 1480 1490 1500
LTGHIGPVMC LTVTQTSNQH DLVVTGSKDH YVKMFQLGDC VTGTIGPTHN
1510 1520 1530 1540 1550
FEPPHYDGIE CLAIQGDILF SGSRDNGIKK WDLDQQELIQ QIPNAHKDWV
1560 1570 1580 1590 1600
CALAFVPGRP MLLSACRAGF IKVWNVDNFT PIGEIKGHDS PINAICTNSK
1610 1620
HIFTASSDLT VKFWSIRRLP AAHP
Length:1,624
Mass (Da):181,401
Last modified:September 21, 2011 - v1
Checksum:i77D2B513FC6E6DA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124550 Genomic DNA. No translation available.
RefSeqiNP_001034561.1. NM_001039472.1.
UniGeneiMm.276135.

Genome annotation databases

EnsembliENSMUST00000075164; ENSMUSP00000074661; ENSMUSG00000041642.
GeneIDi16565.
KEGGimmu:16565.
UCSCiuc007cul.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124550 Genomic DNA. No translation available.
RefSeqiNP_001034561.1. NM_001039472.1.
UniGeneiMm.276135.

3D structure databases

ProteinModelPortaliF8VQE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF8VQE2. 10 interactions.
STRINGi10090.ENSMUSP00000074661.

Proteomic databases

MaxQBiF8VQE2.
PaxDbiF8VQE2.
PRIDEiF8VQE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075164; ENSMUSP00000074661; ENSMUSG00000041642.
GeneIDi16565.
KEGGimmu:16565.
UCSCiuc007cul.1. mouse.

Organism-specific databases

CTDi23046.
MGIiMGI:109234. Kif21b.

Phylogenomic databases

eggNOGiKOG0244. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00840000129683.
KOiK10395.
OrthoDBiEOG708VZ4.
TreeFamiTF105224.

Miscellaneous databases

ChiTaRSiKif21b. mouse.
NextBioi290069.
SOURCEiSearch...

Gene expression databases

BgeeiF8VQE2.
ExpressionAtlasiF8VQE2. baseline and differential.
GenevisibleiF8VQE2. MM.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
IPR009053. Prefoldin.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 5 hits.
PfamiPF00225. Kinesin. 1 hit.
PF00400. WD40. 3 hits.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
SSF50978. SSF50978. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 4 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8VQE2_MOUSE
AccessioniPrimary (citable) accession number: F8VQE2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 11, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.