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Protein
Submitted name:

Pericentrin

Gene

Pcnt

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-2565942. Regulation of PLK1 Activity at G2/M Transition.
R-MMU-380259. Loss of Nlp from mitotic centrosomes.
R-MMU-380270. Recruitment of mitotic centrosome proteins and complexes.
R-MMU-5620912. Anchoring of the basal body to the plasma membrane.

Names & Taxonomyi

Protein namesi
Submitted name:
PericentrinImported
Gene namesi
Name:PcntImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:102722. Pcnt.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiF8VPV0.
PaxDbiF8VPV0.
PRIDEiF8VPV0.

Expressioni

Gene expression databases

BgeeiF8VPV0.
GenevisibleiF8VPV0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001179.

Structurei

3D structure databases

ProteinModelPortaliF8VPV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2719 – 279779PACT_coil_coilInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili198 – 22629Sequence analysisAdd
BLAST
Coiled coili264 – 29835Sequence analysisAdd
BLAST
Coiled coili304 – 34239Sequence analysisAdd
BLAST
Coiled coili474 – 51744Sequence analysisAdd
BLAST
Coiled coili727 – 78458Sequence analysisAdd
BLAST
Coiled coili876 – 91035Sequence analysisAdd
BLAST
Coiled coili1076 – 110631Sequence analysisAdd
BLAST
Coiled coili1128 – 116235Sequence analysisAdd
BLAST
Coiled coili1170 – 119425Sequence analysisAdd
BLAST
Coiled coili1255 – 128935Sequence analysisAdd
BLAST
Coiled coili1327 – 138256Sequence analysisAdd
BLAST
Coiled coili1432 – 147746Sequence analysisAdd
BLAST
Coiled coili1535 – 156228Sequence analysisAdd
BLAST
Coiled coili2212 – 227463Sequence analysisAdd
BLAST
Coiled coili2297 – 233135Sequence analysisAdd
BLAST
Coiled coili2367 – 241246Sequence analysisAdd
BLAST
Coiled coili2453 – 252472Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IJHT. Eukaryota.
ENOG4110FJZ. LUCA.
GeneTreeiENSGT00730000110871.
OMAiSDHPPEQ.
OrthoDBiEOG7DRJ25.
TreeFamiTF336114.

Family and domain databases

InterProiIPR019528. PACT_domain.
IPR024151. Pericentrin.
[Graphical view]
PANTHERiPTHR18937:SF204. PTHR18937:SF204. 11 hits.
PfamiPF10495. PACT_coil_coil. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8VPV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDEQEQRRR KVEAGRAKLA NFRQRKTKGD CPNSKKKTAK RKGSAVHASV
60 70 80 90 100
QEEGSVATPN SELPQGGAVF ESPSCSNTLE GTRGASAAQE QEDCELDVTD
110 120 130 140 150
LQGQQQTQPP PPQTAHSLEL EALRLSLNNM HTAQLELTQA NLQKEKETAL
160 170 180 190 200
TELREMLNGR RAQELALLQS RQQCELELLR EQHAREKEEM ALRSGQEAAE
210 220 230 240 250
LKEKLRSEME KNAQTIETLK QDWESERELC LENLRQELSL KHQSEMEGLQ
260 270 280 290 300
SQFQKELSEQ KVELEKIFQA KHEAEVSLKN LEAQHQAAIK KLQEDLQSEH
310 320 330 340 350
CQYLQDLEQK FREKEKAKEL ELETLQASYE DLKAQSQEEI RLLWSQLESM
360 370 380 390 400
KTNREELNGS WDPVLAQASH LEELEHLRSG FAQQQQQERA QHESELEHLR
410 420 430 440 450
VYFEKKLKDA EKTYQEDLTV FQQRLQEARE DSLESTEISS SCVLPEETSG
460 470 480 490 500
REGKEPPDPL DLQLGQPKVQ ESLVEDCQVK LSKAEEKIQQ MKEEFQKKEA
510 520 530 540 550
EWELSREELK REAEERLASM FLELREKAES EKLSIISRFE HRESSMRHLQ
560 570 580 590 600
DQQAAQILDL ERSLMEQQGH LRQLEQELTR DDLLPCSQCG QEPAMAQEEK
610 620 630 640 650
NGALLREKED CALQLLMAQN RFLEERKEIM EKFAKEQDAF LRDAQEKHNH
660 670 680 690 700
ELQLLQQGHQ QQLLALRMEL ETKHRSELTE QLASSESRRQ ALLETHVAEL
710 720 730 740 750
QVKHNAEISA LEKRHLSNLD ELESCYVADV QTIRDEHQQA LELLRAELEE
760 770 780 790 800
QLQKKESCHR EMLTQELENL KRQHAEELQS VRDSLRMEMS AQHIENGKGP
810 820 830 840 850
AADLQGAHQQ DPAMALHNEG HLLVEDGDAV LRSVDAEGLL HQAGPQELGD
860 870 880 890 900
AHTVEMQKSQ AELAKPQELQ ASQDQVAQVR DKVFLLNREL EECRAELEQL
910 920 930 940 950
QQRRERENQE GTTLICMLRA DLELAQGEGK ALRDALRRLL DLFGDTLKAA
960 970 980 990 1000
VTLKSRISER AGLLLDHEDA ADTSDARLAA AALGDMWSDE GLLEIDRTLP
1010 1020 1030 1040 1050
EGAETSSVCE ISSHVCESFF ISPENTLDCE QPIRRVYQSL STAVEGLLEM
1060 1070 1080 1090 1100
ALDSSKQLEE ARQLHRCVER EFRHRNEEMA QAMQKQQELL ERLREESAAK
1110 1120 1130 1140 1150
DRLALELHTA KGLLEGFKVE KVDLQEALGK KEESEQQLIL ELEDLRKQLQ
1160 1170 1180 1190 1200
QAARELLTLK EEKSVLWNQK ETLTNEAKER EAALQEEVES LTRVQWESRK
1210 1220 1230 1240 1250
QSEKDRATLL SQMRVLESEL EDQLVQHRGC AQLAEEVATL KQQLAALDKH
1260 1270 1280 1290 1300
LRSQRQFMDD QAAEREHERE EFQQEIQRLE GQLRQAARPR PPGPRDSQCV
1310 1320 1330 1340 1350
QLDEEVELLQ EKLREKLDGF NELVIKKDFA DQQLLIQEEE IKRLEETNAS
1360 1370 1380 1390 1400
IQRQMVQLQE ELEKQKKSME ELKEKEILKQ ENMGDLLLTT VSRSGLDEAG
1410 1420 1430 1440 1450
CPMLPQGSSS RGPEAQPDVT ERALLQHENE VVHRRNSEID ELKSLIENLQ
1460 1470 1480 1490 1500
ENQRQLQKDK AEEIEQLHEV IEKLQSELSL MGPKVHEVSD PQAGSLHSEL
1510 1520 1530 1540 1550
ACLRGEGLGG QALRSELQAA QAAKEVFGQL LADQAHGHSQ ALEALQQRLQ
1560 1570 1580 1590 1600
DAEEVAARHL AELEHCVALR EAEVEAMASQ IQEFAATLKA KEAIIEQRDL
1610 1620 1630 1640 1650
EIDAVNKWKV SHSLELEAIL LALAHFRHAL EQQTCATPDE PPELRQLRVQ
1660 1670 1680 1690 1700
CARLSHQLQV LYRPFLKCRM QLDQHQPHVA SIGCANPCAD DELEQEGVSN
1710 1720 1730 1740 1750
RLALAPHSLA AQAKEELEDC PLGKANLMAQ VRQLQEELDH RVHSVASRDT
1760 1770 1780 1790 1800
NSETCKLQQP NLSENGPRNH CCNGEESKPS PPDDVLNIAK TTWDVIDIIK
1810 1820 1830 1840 1850
NQDLLVQVEM PDFPTQEKLT SQGGPFSSQA SGHSGSLLPE EAAEPQQDPV
1860 1870 1880 1890 1900
RALDLSSWSS PEVVRKDPSL EPQHSLPLTP GVGTVSLHSV DISPDWTDPL
1910 1920 1930 1940 1950
LQADVSGLLC YPGKSASGQA PLWAVAPSAG KHHAERTATE KDVEDFIVTS
1960 1970 1980 1990 2000
FDSQELLTSP SHELARRSDG SRKSDGPDIA MMLTLGSEGS ETPTTDLVAA
2010 2020 2030 2040 2050
AAAAVPFSRR FVQSPGAMKE KEIHAKQMKA LLQMVFDESH QILALSESQD
2060 2070 2080 2090 2100
PSSALNKGEP RDPLDGFPRD SQALSEVTTD KGEKESLETH LTWSEELLRA
2110 2120 2130 2140 2150
IQEVFAREQE KAELQPRPYG SNLGDYNSLV QRLEKVIQEQ GDPQKVQDHL
2160 2170 2180 2190 2200
CLSDRSSLLA EIQALRAQLR MTHLQNQEKL QQLCAALTST EARGSQREHQ
2210 2220 2230 2240 2250
LRRQVELLAY KVEQEKCIAN ELQKTLSKEQ ETASDVRKRL VVEQNAVQDL
2260 2270 2280 2290 2300
KSELHACKQE NTSLLESLDK VQQEVLRLRY GHVTWSYCGT SSASAGRAVL
2310 2320 2330 2340 2350
DGKEKELKVV LEELESERGK GQALQAQQEE QQLRYLQREG QSSRALEELK
2360 2370 2380 2390 2400
LSLEKQLAQN NQLCVALKHE RAAKDNLQKE LQIEASRCEA LLAQEKGQLS
2410 2420 2430 2440 2450
ELQKSLEAER SRSLELSEAL QHERLLTEQL SRNSQEACAR QETQVQHALL
2460 2470 2480 2490 2500
RKLKAEKTRA LELEAMLEKV QKQAAHTQQQ LEAQAQERCV ELRREKEREL
2510 2520 2530 2540 2550
EIQRQRDEHK IEQLQRLVRE LRWKEEVSGG NGPCRGSPGR GSLERDQFQE
2560 2570 2580 2590 2600
QQQELEKIRQ QLLCAAGLLT SFTNHTVDRT IKDWTSSNEK AVSSLMRTLE
2610 2620 2630 2640 2650
ELKSELSMPT SFQKKMTAEL QVQLMNELLS DNDALTKAVG MATREKAELC
2660 2670 2680 2690 2700
RTVSRLEKTL KHHTQKGCVL NRQSKSSLKQ DGTDLQSSLR HSDPEWHSQT
2710 2720 2730 2740 2750
TSGDTNTCNI KMEKLYLHYL RAESFRKALI YQKKYLLLLI GGFQDSEQET
2760 2770 2780 2790 2800
LSMIAHLGVF PSKADKKITM SRPFTKFRTA VRVVIAVLRL RFLVKKWQEV
2810 2820 2830 2840 2850
DRKGALVHPK STRHGHRTSQ RQRSPSGPRA SLPTRDTSSG PTKASRHSPR
2860 2870 2880 2890 2900
SAAAGSPGKE RSTSTPSSRL ERSLTASQDP EHSLTEYIHH LEMIQQRLGG
2910
LPPDSTQKSC HQKIKQ
Length:2,916
Mass (Da):331,338
Last modified:September 21, 2011 - v1
Checksum:i9969780DFEFFE8D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC141477 Genomic DNA. No translation available.
AC158618 Genomic DNA. No translation available.
RefSeqiNP_032813.3. NM_008787.3.
UniGeneiMm.251794.

Genome annotation databases

EnsembliENSMUST00000001179; ENSMUSP00000001179; ENSMUSG00000001151.
GeneIDi18541.
UCSCiuc007fuk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC141477 Genomic DNA. No translation available.
AC158618 Genomic DNA. No translation available.
RefSeqiNP_032813.3. NM_008787.3.
UniGeneiMm.251794.

3D structure databases

ProteinModelPortaliF8VPV0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001179.

Proteomic databases

MaxQBiF8VPV0.
PaxDbiF8VPV0.
PRIDEiF8VPV0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000001179; ENSMUSP00000001179; ENSMUSG00000001151.
GeneIDi18541.
UCSCiuc007fuk.1. mouse.

Organism-specific databases

CTDi5116.
MGIiMGI:102722. Pcnt.

Phylogenomic databases

eggNOGiENOG410IJHT. Eukaryota.
ENOG4110FJZ. LUCA.
GeneTreeiENSGT00730000110871.
OMAiSDHPPEQ.
OrthoDBiEOG7DRJ25.
TreeFamiTF336114.

Enzyme and pathway databases

ReactomeiR-MMU-2565942. Regulation of PLK1 Activity at G2/M Transition.
R-MMU-380259. Loss of Nlp from mitotic centrosomes.
R-MMU-380270. Recruitment of mitotic centrosome proteins and complexes.
R-MMU-5620912. Anchoring of the basal body to the plasma membrane.

Miscellaneous databases

NextBioi294320.
SOURCEiSearch...

Gene expression databases

BgeeiF8VPV0.
GenevisibleiF8VPV0. MM.

Family and domain databases

InterProiIPR019528. PACT_domain.
IPR024151. Pericentrin.
[Graphical view]
PANTHERiPTHR18937:SF204. PTHR18937:SF204. 11 hits.
PfamiPF10495. PACT_coil_coil. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8VPV0_MOUSE
AccessioniPrimary (citable) accession number: F8VPV0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 11, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.