Crebbp

Functionⁱ

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	1494	Acetyl-CoA; via carbonyl oxygenPROSITE-ProRule annotation	1
Binding siteⁱ	1499	Acetyl-CoAPROSITE-ProRule annotation	1
Binding siteⁱ	1503	Acetyl-CoAPROSITE-ProRule annotation	1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	346 – 432	TAZ-typePROSITE-ProRule annotationAdd BLAST		87
Zinc fingerⁱ	1766 – 1847	TAZ-typePROSITE-ProRule annotationAdd BLAST		82

GO - Molecular functionⁱ

chromatin binding Source: Ensembl
damaged DNA binding Source: Ensembl
histone acetyltransferase activity Source: UniProtKB-UniRule
MRF binding Source: Ensembl
p53 binding Source: Ensembl
proximal promoter sequence-specific DNA binding Source: Ensembl
RNA polymerase II transcription factor binding Source: Ensembl
transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl
transcriptional repressor activity, RNA polymerase II transcription factor binding Source: Ensembl
transcription coactivator activity Source: Ensembl
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to UV Source: Ensembl
N-terminal peptidyl-lysine acetylation Source: Ensembl
positive regulation of transcription, DNA-templated Source: Ensembl
protein destabilization Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	AcyltransferasePROSITE-ProRule annotation, Transferase
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-MMU-3371568 Attenuation phase R-MMU-350054 Notch-HLH transcription pathway R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-MMU-5621575 CD209 (DC-SIGN) signaling R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-MMU-8941856 RUNX3 regulates NOTCH signaling R-MMU-918233 TRAF3-dependent IRF activation pathway R-MMU-933541 TRAF6 mediated IRF7 activation R-MMU-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor
R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-MMU-3371568 Attenuation phase
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-5621575 CD209 (DC-SIGN) signaling
R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
R-MMU-8941856 RUNX3 regulates NOTCH signaling
R-MMU-918233 TRAF3-dependent IRF activation pathway
R-MMU-933541 TRAF6 mediated IRF7 activation
R-MMU-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: CREB-binding proteinImported
Gene namesⁱ	Name:CrebbpImported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 16

Organism-specific databases

MGIⁱ	MGI:1098280 Crebbp

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	F8VPR5
PeptideAtlas More...PeptideAtlasⁱ	F8VPR5
PRIDEⁱ	F8VPR5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000022521
ExpressionAtlasⁱ	F8VPR5 baseline and differential
Genevisibleⁱ	F8VPR5 MM

Interactionⁱ

GO - Molecular functionⁱ

MRF binding Source: Ensembl
p53 binding Source: Ensembl
RNA polymerase II transcription factor binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

IntActⁱ	F8VPR5 14 interactors.

IntActⁱ

F8VPR5 14 interactors.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	F8VPR5
SMRⁱ	F8VPR5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	346 – 432	TAZ-typeInterPro annotationAdd BLAST	87
Domainⁱ	586 – 665	KIXInterPro annotationAdd BLAST	80
Domainⁱ	1104 – 1176	BromoInterPro annotationAdd BLAST	73
Domainⁱ	1324 – 1701	CBP/p300-type HATInterPro annotationAdd BLAST	378
Domainⁱ	1702 – 1745	ZZ-typeInterPro annotationAdd BLAST	44
Domainⁱ	1766 – 1847	TAZ-typeInterPro annotationAdd BLAST	82

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	1435 – 1437	Acetyl-CoA bindingPROSITE-ProRule annotation		3
Regionⁱ	1447 – 1448	Acetyl-CoA bindingPROSITE-ProRule annotation		2

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	1550 – 1574	Sequence analysisAdd BLAST		25
Coiled coilⁱ	2191 – 2216	Sequence analysisAdd BLAST		26

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	346 – 432	TAZ-typePROSITE-ProRule annotationAdd BLAST		87
Zinc fingerⁱ	1766 – 1847	TAZ-typePROSITE-ProRule annotationAdd BLAST		82

Keywords - Domainⁱ

BromodomainPROSITE-ProRule annotationSAAS annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1778 Eukaryota COG5076 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119206
KEGG Orthology (KO) More...KOⁱ	K04498
OMAⁱ	SGHSLMN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0L04
TreeFamⁱ	TF101097

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd15802 RING_CBP-p300, 1 hit
Gene3Dⁱ	1.10.1630.101 hit 1.20.1020.102 hits 1.20.920.101 hit 2.10.110.401 hit 3.30.40.101 hit
InterProⁱ	View protein in InterPro IPR001487 Bromodomain IPR036427 Bromodomain-like_sf IPR018359 Bromodomain_CS IPR031162 CBP_P300_HAT IPR013178 Histone_AcTrfase_Rtt109/CBP IPR003101 KIX_dom IPR036529 KIX_dom_sf IPR009110 Nuc_rcpt_coact IPR014744 Nuc_rcpt_coact_CREBbp IPR037073 Nuc_rcpt_coact_CREBbp_sf IPR010303 RING_CBP-p300 IPR038547 RING_CBP-p300_sf IPR035898 TAZ_dom_sf IPR013083 Znf_RING/FYVE/PHD IPR000197 Znf_TAZ IPR000433 Znf_ZZ
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00439 Bromodomain, 1 hit PF09030 Creb_binding, 1 hit PF06001 DUF902, 1 hit PF08214 HAT_KAT11, 1 hit PF02172 KIX, 1 hit PF02135 zf-TAZ, 2 hits PF00569 ZZ, 1 hit
PRINTSⁱ	PR00503 BROMODOMAIN
SMARTⁱ	View protein in SMART SM00297 BROMO, 1 hit SM01250 KAT11, 1 hit SM00551 ZnF_TAZ, 2 hits SM00291 ZnF_ZZ, 1 hit
SUPFAMⁱ	SSF47040 SSF47040, 1 hit SSF47370 SSF47370, 1 hit SSF57933 SSF57933, 2 hits SSF69125 SSF69125, 1 hit
PROSITEⁱ	View protein in PROSITE PS00633 BROMODOMAIN_1, 1 hit PS50014 BROMODOMAIN_2, 1 hit PS51727 CBP_P300_HAT, 1 hit PS50952 KIX, 1 hit PS50134 ZF_TAZ, 2 hits PS01357 ZF_ZZ_1, 1 hit PS50135 ZF_ZZ_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

F8VPR5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAENLLDGPP NPKRAKLSSP GFSANDNTDF GSLFDLENDL PDELIPNGEL 
        60         70         80         90        100
SLLNSGNLVP DAASKHKQLS ELLRGGSGSS INPGIGNVSA SSPVQQGLGG 
       110        120        130        140        150
QAQGQPNSTN MASLGAMGKS PLNQGDSSTP NLPKQAASTS GPTPPASQAL 
       160        170        180        190        200
NPQAQKQVGL VTSSPATSQT GPGICMNANF NQTHPGLLNS NSGHSLMNQA 
       210        220        230        240        250
QQGQAQVMNG SLGAAGRGRG AGMPYPAPAM QGATSSVLAE TLTQVSPQMA 
       260        270        280        290        300
GHAGLNTAQA GGMTKMGMTG TTSPFGQPFS QTGGQQMGAT GVNPQLASKQ 
       310        320        330        340        350
SMVNSLPAFP TDIKNTSVTT VPNMSQLQTS VGIVPTQAIA TGPTADPEKR 
       360        370        380        390        400
KLIQQQLVLL LHAHKCQRRE QANGEVRACS LPHCRTMKNV LNHMTHCQAG 
       410        420        430        440        450
KACQVAHCAS SRQIISHWKN CTRHDCPVCL PLKNASDKRN QQTILGSPAS 
       460        470        480        490        500
GIQNTIGSVG AGQQNATSLS NPNPIDPSSM QRAYAALGLP YMNQPQTQLQ 
       510        520        530        540        550
PQVPGQQPAQ PPAHQQMRTL NALGNNPMSI PAGGITTDQQ PPNLISESAL 
       560        570        580        590        600
PTSLGATNPL MNDGSNSGNI GSLSTIPTAA PPSSTGVRKG WHEHVTQDLR 
       610        620        630        640        650
SHLVHKLVQA IFPTPDPAAL KDRRMENLVA YAKKVEGDMY ESANSRDEYY 
       660        670        680        690        700
HLLAEKIYKI QKELEEKRRS RLHKQGILGN QPALPASGAQ PPVIPPAQSV 
       710        720        730        740        750
RPPNGPLPLP VNRMQVSQGM NSFNPMSLGN VQLPQAPMGP RAASPMNHSV 
       760        770        780        790        800
QMNSMASVPG MAISPSRMPQ PPNMMGTHAN NIMAQAPTQN QFLPQNQFPS 
       810        820        830        840        850
SSGAMSVNSV GMGQPAAQAG VSQGQVPGAA LPNPLNMLAP QASQLPCPPV 
       860        870        880        890        900
TQSPLHPTPP PASTAAGMPS LQHPTAPGMT PPQPAAPTQP STPVSSGQTP 
       910        920        930        940        950
TPTPGSVPSA AQTQSTPTVQ AAAQAQVTPQ PQTPVQPPSV ATPQSSQQQP 
       960        970        980        990       1000
TPVHTQPPGT PLSQAAASID NRVPTPSSVT SAETSSQQPG PDVPMLEMKT 
      1010       1020       1030       1040       1050
EVQTDDAEPE PTESKGEPRS EMMEEDLQGS SQVKEETDTT EQKSEPMEVE 
      1060       1070       1080       1090       1100
EKKPEVKVEA KEEEENSSND TASQSTSPSQ PRKKIFKPEE LRQALMPTLE 
      1110       1120       1130       1140       1150
ALYRQDPESL PFRQPVDPQL LGIPDYFDIV KNPMDLSTIK RKLDTGQYQE 
      1160       1170       1180       1190       1200
PWQYVDDVWL MFNNAWLYNR KTSRVYKFCS KLAEVFEQEI DPVMQSLGYC 
      1210       1220       1230       1240       1250
CGRKYEFSPQ TLCCYGKQLC TIPRDAAYYS YQNRYHFCEK CFTEIQGENV 
      1260       1270       1280       1290       1300
TLGDDPSQPQ TTISKDQFEK KKNDTLDPEP FVDCKECGRK MHQICVLHYD 
      1310       1320       1330       1340       1350
IIWPSGFVCD NCLKKTGRPR KENKFSAKRL QTTRLGNHLE DRVNKFLRRQ 
      1360       1370       1380       1390       1400
NHPEAGEVFV RVVASSDKTV EVKPGMKSRF VDSGEMSESF PYRTKALFAF 
      1410       1420       1430       1440       1450
EEIDGVDVCF FGMHVQEYGS DCPPPNTRRV YISYLDSIHF FRPRCLRTAV 
      1460       1470       1480       1490       1500
YHEILIGYLE YVKKLGYVTG HIWACPPSEG DDYIFHCHPP DQKIPKPKRL 
      1510       1520       1530       1540       1550
QEWYKKMLDK AFAERIINDY KDIFKQANED RLTSAKELPY FEGDFWPNVL 
      1560       1570       1580       1590       1600
EESIKELEQE EEERKKEEST AASETPEGSQ GDSKNAKKKN NKKTNKNKSS 
      1610       1620       1630       1640       1650
ISRANKKKPS MPNVSNDLSQ KLYATMEKHK EVFFVIHLHA GPVISTQPPI 
      1660       1670       1680       1690       1700
VDPDPLLSCD LMDGRDAFLT LARDKHWEFS SLRRSKWSTL CMLVELHTQG 
      1710       1720       1730       1740       1750
QDRFVYTCNE CKHHVETRWH CTVCEDYDLC INCYNTKSHT HKMVKWGLGL 
      1760       1770       1780       1790       1800
DDEGSSQGEP QSKSPQESRR LSIQRCIQSL VHACQCRNAN CSLPSCQKMK 
      1810       1820       1830       1840       1850
RVVQHTKGCK RKTNGGCPVC KQLIALCCYH AKHCQENKCP VPFCLNIKHK 
      1860       1870       1880       1890       1900
LRQQQIQHRL QQAQLMRRRM ATMNTRNVPQ QSLPSPTSAP PGTPTQQPST 
      1910       1920       1930       1940       1950
PQTPQPPAQP QPSPVNMSPA GFPNVARTQP PTIVSAGKPT NQVPAPPPPA 
      1960       1970       1980       1990       2000
QPPPAAVEAA RQIEREAQQQ QHLYRANINN GMPPGRAGMG TPGSQMTPVG 
      2010       2020       2030       2040       2050
LNVPRPNQVS GPVMSSMPPG QWQQAPIPQQ QPMPGMPRPV MSMQAQAAVA 
      2060       2070       2080       2090       2100
GPRMPNVQPP RSISPSALQD LLRTLKSPSS PQQQQQVLNI LKSNPQLMAA 
      2110       2120       2130       2140       2150
FIKQRTAKYV ANQPGMQPQP GLQSQPGMQP QPGMHQQPSL QNLNAMQAGV 
      2160       2170       2180       2190       2200
PRPGVPPPQP AMGGLNPQGQ ALNIMNPGHN PNMTNMNPQY REMVRRQLLQ 
      2210       2220       2230       2240       2250
HQQQQQQQQQ QQQQQQNSAS LAGGMAGHSQ FQQPQGPGGY APAMQQQRMQ 
      2260       2270       2280       2290       2300
QHLPIQGSSM GQMAAPMGQL GQMGQPGLGA DSTPNIQQAL QQRILQQQQM 
      2310       2320       2330       2340       2350
KQQIGSPGQP NPMSPQQHML SGQPQASHLP GQQIATSLSN QVRSPAPVQS 
      2360       2370       2380       2390       2400
PRPQSQPPHS SPSPRIQPQP SPHHVSPQTG SPHPGLAVTM ASSMDQGHLG 
      2410       2420       2430       2440 
NPEQSAMLPQ LNTPNRSALS SELSLVGDTT GDTLEKFVEG L

Length:2,441

Mass (Da):265,567

Last modified:September 21, 2011 - v1

Checksum:ⁱ79A370F30FFB2A7C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC132380 Genomic DNA No translation available. AC132575 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001020603.1, NM_001025432.1
UniGeneⁱ	Mm.132238 Mm.392384

Genome annotation databases

Ensemblⁱ	ENSMUST00000023165; ENSMUSP00000023165; ENSMUSG00000022521
GeneIDⁱ	12914
KEGGⁱ	mmu:12914
UCSC genome browser More...UCSCⁱ	uc007xzl.1 mouse

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
F8VPR5	Q8QZV8	Mus musculus (Mouse)	2,441	UniRef100_F8VPR5	Cluster: CREB-binding protein	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
F8VPR5	Q92793 UPI000B7B9A3F UPI0005F4E2BF UPI000A340EFC UPI000C2F85CA UPI0005405EC7 UPI00075FAD67 UPI00075FB366 UPI00083EE2CC UPI000BAA0EAB +158	Homo sapiens (Human) Papio anubis (Olive baboon) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Heterocephalus glaber (Naked mole rat) Felis catus (Cat) (Felis silvestris catus) Loxodonta africana (African elephant) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Canis lupus familiaris (Dog) (Canis familiaris) Equus caballus (Horse) Microcebus murinus (Lesser mouse lemur) (Gray Mouse Lemur) And more	2,442	UniRef90_Q92793	Cluster: CREB-binding protein	169

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
F8VPR5	Q92793 UPI000B7B9A3F UPI0005F4E2BF UPI000A340EFC UPI000C2F85CA UPI0005405EC7 UPI00083EE2CC UPI000BAA0EAB UPI000C9E166C UPI000C9E5763 +213	Homo sapiens (Human) Papio anubis (Olive baboon) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Heterocephalus glaber (Naked mole rat) Felis catus (Cat) (Felis silvestris catus) Loxodonta africana (African elephant) Canis lupus familiaris (Dog) (Canis familiaris) Equus caballus (Horse) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Microcebus murinus (Lesser mouse lemur) (Gray Mouse Lemur) And more	2,442	UniRef50_Q92793	Cluster: CREB-binding protein	224

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC132380 Genomic DNA No translation available. AC132575 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001020603.1, NM_001025432.1
UniGeneⁱ	Mm.132238 Mm.392384

3D structure databases

ProteinModelPortalⁱ	F8VPR5
SMRⁱ	F8VPR5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	F8VPR5 14 interactors.

IntActⁱ

F8VPR5 14 interactors.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	F8VPR5
PeptideAtlas More...PeptideAtlasⁱ	F8VPR5
PRIDEⁱ	F8VPR5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000023165; ENSMUSP00000023165; ENSMUSG00000022521
GeneIDⁱ	12914
KEGGⁱ	mmu:12914
UCSC genome browser More...UCSCⁱ	uc007xzl.1 mouse

Organism-specific databases

CTDⁱ	1387
MGIⁱ	MGI:1098280 Crebbp

Phylogenomic databases

eggNOGⁱ	KOG1778 Eukaryota COG5076 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119206
KEGG Orthology (KO) More...KOⁱ	K04498
OMAⁱ	SGHSLMN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0L04
TreeFamⁱ	TF101097

Enzyme and pathway databases

Reactomeⁱ	R-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-MMU-3371568 Attenuation phase R-MMU-350054 Notch-HLH transcription pathway R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-MMU-5621575 CD209 (DC-SIGN) signaling R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-MMU-8941856 RUNX3 regulates NOTCH signaling R-MMU-918233 TRAF3-dependent IRF activation pathway R-MMU-933541 TRAF6 mediated IRF7 activation R-MMU-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor
R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-MMU-3371568 Attenuation phase
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-5621575 CD209 (DC-SIGN) signaling
R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
R-MMU-8941856 RUNX3 regulates NOTCH signaling
R-MMU-918233 TRAF3-dependent IRF activation pathway
R-MMU-933541 TRAF6 mediated IRF7 activation
R-MMU-983231 Factors involved in megakaryocyte development and platelet production

Miscellaneous databases

ChiTaRSⁱ	Crebbp mouse
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022521
ExpressionAtlasⁱ	F8VPR5 baseline and differential
Genevisibleⁱ	F8VPR5 MM

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd15802 RING_CBP-p300, 1 hit
Gene3Dⁱ	1.10.1630.101 hit 1.20.1020.102 hits 1.20.920.101 hit 2.10.110.401 hit 3.30.40.101 hit
InterProⁱ	View protein in InterPro IPR001487 Bromodomain IPR036427 Bromodomain-like_sf IPR018359 Bromodomain_CS IPR031162 CBP_P300_HAT IPR013178 Histone_AcTrfase_Rtt109/CBP IPR003101 KIX_dom IPR036529 KIX_dom_sf IPR009110 Nuc_rcpt_coact IPR014744 Nuc_rcpt_coact_CREBbp IPR037073 Nuc_rcpt_coact_CREBbp_sf IPR010303 RING_CBP-p300 IPR038547 RING_CBP-p300_sf IPR035898 TAZ_dom_sf IPR013083 Znf_RING/FYVE/PHD IPR000197 Znf_TAZ IPR000433 Znf_ZZ
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00439 Bromodomain, 1 hit PF09030 Creb_binding, 1 hit PF06001 DUF902, 1 hit PF08214 HAT_KAT11, 1 hit PF02172 KIX, 1 hit PF02135 zf-TAZ, 2 hits PF00569 ZZ, 1 hit
PRINTSⁱ	PR00503 BROMODOMAIN
SMARTⁱ	View protein in SMART SM00297 BROMO, 1 hit SM01250 KAT11, 1 hit SM00551 ZnF_TAZ, 2 hits SM00291 ZnF_ZZ, 1 hit
SUPFAMⁱ	SSF47040 SSF47040, 1 hit SSF47370 SSF47370, 1 hit SSF57933 SSF57933, 2 hits SSF69125 SSF69125, 1 hit
PROSITEⁱ	View protein in PROSITE PS00633 BROMODOMAIN_1, 1 hit PS50014 BROMODOMAIN_2, 1 hit PS51727 CBP_P300_HAT, 1 hit PS50952 KIX, 1 hit PS50134 ZF_TAZ, 2 hits PS01357 ZF_ZZ_1, 1 hit PS50135 ZF_ZZ_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F8VPR5_MOUSE
Accessionⁱ	F8VPR5Primary (citable) accession number: F8VPR5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 21, 2011
	Last sequence update:	September 21, 2011
	Last modified:	April 25, 2018
	This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F8VPR5 (F8VPR5_MOUSE)

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CREB-binding protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Coiled coil

Zinc finger

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ