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Protein
Submitted name:

Eukaryotic translation initiation factor 4B

Gene

EIF4B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 4BImported
Gene namesi
Name:EIF4BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000063046.17.
HGNCiHGNC:3285. EIF4B.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000063046.

PTM / Processingi

Proteomic databases

MaxQBiF8VP89.
PeptideAtlasiF8VP89.
PRIDEiF8VP89.

Expressioni

Gene expression databases

BgeeiENSG00000063046.
ExpressionAtlasiF8VP89. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8VP89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 173RRMInterPro annotationAdd BLAST78

Phylogenomic databases

GeneTreeiENSGT00530000063406.

Family and domain databases

InterProiView protein in InterPro
IPR033107. EIF-4B.
IPR035979. RBD_domain_sf.
IPR000504. RRM_dom.
PANTHERiPTHR23236:SF2. PTHR23236:SF2. 1 hit.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.

Sequencei

Sequence statusi: Fragment.

F8VP89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASAKKKNK KGKTISLTDF LAEDGGTGGG STYVSKPVSW ADETDDLEGD
60 70 80 90 100
VSTTWHSNDD DVYRAPPIDR SILPTAPRAA REPNIDRSRL PKSPPYTAFL
110 120 130 140 150
GNLPYDVTEE SIKEFFRGLN ISAVRLPREP SNPERLKGFG YAEFEDLDSL
160 170 180 190 200
LSALSLNEES LGNRRIRVDV ADQAQDKDRD DRSFGRDRNR DSDKTDTDWR
210 220 230 240 250
ARPATDSFDD YPPRRGDDSF GDSYDSRIGS GRRAFGSGYR RDDDYRGGGD
260 270
RYEDRYDRRD DRSWSSRDDY SRDDY
Length:275
Mass (Da):31,221
Last modified:September 21, 2011 - v1
Checksum:iED738D306CF15752
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei275Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068888 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000552490; ENSP00000450324; ENSG00000063046.
UCSCiuc058ojy.1. human.

Similar proteinsi

Entry informationi

Entry nameiF8VP89_HUMAN
AccessioniPrimary (citable) accession number: F8VP89
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 25, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported