F8VEJ4 (F8VEJ4_SALBC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-hexosaminidase HAMAP-Rule MF_00364
EC=3.2.1.52 HAMAP-Rule MF_00364

Alternative name(s):
Beta-N-acetylhexosaminidase HAMAP-Rule MF_00364
N-acetyl-beta-glucosaminidase HAMAP-Rule MF_00364

Gene names

Name:	nagZ HAMAP-Rule MF_00364
Ordered Locus Names:	SBG_1047 EMBL CCC30143.1

Organism

Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419) [Complete proteome] [HAMAP] EMBL CCC30143.1

Taxonomic identifier

218493 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella bongori

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity. HAMAP-Rule MF_00364 SAAS SAAS001764
Catalytic activity	Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP-Rule MF_00364 SAAS SAAS001764
Pathway	Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_00364 SAAS SAAS001764
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00364 SAAS SAAS001764.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. HAMAP-Rule MF_00364

Ontologies

Keywords
Biological process	Cell cycle Cell division HAMAP-Rule MF_00364 SAAS SAAS001764 Cell shape Cell wall biogenesis/degradation HAMAP-Rule MF_00364 SAAS SAAS001764 Peptidoglycan synthesis SAAS SAAS001764 HAMAP-Rule MF_00364
Cellular component	Cytoplasm HAMAP-Rule MF_00364 SAAS SAAS001764
Molecular function	Glycosidase SAAS SAAS022956 HAMAP-Rule MF_00364 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan turnover Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	beta-N-acetylhexosaminidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	248	1	By similarity HAMAP-Rule MF_00364

Sequences

	Sequence		Length	Mass (Da)
	F8VEJ4 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: F6BF5C3589A048B3	FASTA	341	37,605
	10 20 30 40 50 60 MGPVMLNVEG CELDAEEREI LAHPLVGGLI LFTRNYHDPE QLRELVRQIR AASRNHLVVA 70 80 90 100 110 120 VDQEGGRVQR FREGFTRLPA AQSFFALLGQ EEGGRLAQEA GWLMASEMIA MDIDISFAPV 130 140 150 160 170 180 LDVGHISAAI GERAYHADPT KVLAMATRFI DGMHDAGMKT TGKHFPGHGA VTADSHKETP 190 200 210 220 230 240 CDPRPEAVIR DKDMSVFRTL ISENKLDAIM PAHVIYSAVD SRPASGSPHW LKTVLRQELG 250 260 270 280 290 300 FDGVIFSDDL SMEGAAIMGS YAERAQASLD AGCDMILVCN NRKGAVSVLD NLSPIKAERV 310 320 330 340 THLYHKGSFS RRELMDSARW KTASAQLNQL HERWQEEKAG H

References

[1]

"Salmonella bongori provides insights into the evolution of the Salmonellae." Fookes M., Schroeder G.N., Langridge G.C., Blondel C.J., Mammina C., Connor T.R., Seth-Smith H., Vernikos G.S., Robinson K.S., Sanders M., Petty N.K., Kingsley R.A., Baumler A.J., Nuccio S.P., Contreras I., Santiviago C.A., Maskell D., Barrow P. , Humphrey T., Nastasi A., Roberts M., Frankel G., Parkhill J., Dougan G., Thomson N.R. PLoS Pathog. 7:E1002191-E1002191(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43975 / DSM 13772 / NCTC 12419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR877557 Genomic DNA. Translation: CCC30143.1.
RefSeq	YP_004729929.1. NC_015761.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10967214.
KEGG	sbg:SBG_1047.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01207.
Enzyme and pathway databases
BioCyc	SBON218493:GJAH-1071-MONOMER.
UniPathway	UPA00544.
Family and domain databases
Gene3D	3.20.20.300. 1 hit.
HAMAP	MF_00364. NagZ.
InterPro	IPR022956. Beta_hexosaminidase_bac. IPR019800. Glyco_hydro_3_AS. IPR001764. Glyco_hydro_3_N. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF00933. Glyco_hydro_3. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F8VEJ4_SALBC

Accession

Primary (citable) accession number: F8VEJ4

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	March 6, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)