F8M7L9 (F8M7L9_MYCA0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative glutamate decarboxylase GADB EMBL CCC28516.1
EC=4.1.1.15 EMBL CCC28516.1

Gene names

Name:	gadB EMBL CCC28516.1
Ordered Locus Names:	MAF_34470

Organism

Mycobacterium africanum (strain GM041182) [Complete proteome] [HAMAP] EMBL CCC28516.1

Taxonomic identifier

572418 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium africanum

Protein attributes

Sequence length	460 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL CCC28516.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F8M7L9 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: B5DA3156D4C7CB4F	FASTA	460	50,780
	10 20 30 40 50 60 MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM LDGSSRLNLA 70 80 90 100 110 120 TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV SMVADLFHAE GLRDHDPTSA 130 140 150 160 170 180 TGVSTIGSSE AVMLGGLALK WRWRQRVGSW KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY 190 200 210 220 230 240 LPMERGRYVI TPEQVLAAVD ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP 250 260 270 280 290 300 VHVDAASGGF VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 310 320 330 340 350 360 VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT ARWLGDQLRE 370 380 390 400 410 420 VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW QVPAYTMPDN ATDVAVLRIV 430 440 450 460 VREGLSADLA RALHDDAVTA LAALDKVKPG GHFDAQHFAH

References

[1]

"The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and features of genome erosion shared with other members of the tuberculosis complex." Bentley S.D., Comas I., Walker D., Smith N.H., Harris S.R., Thurston S., Gagneux S., Wood J., Antonio M., Quail M.A., Gehre F., Adegbola R.A., Parkhill J., De Jong B.C. Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GM041182.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR878060 Genomic DNA. Translation: CCC28516.1.
RefSeq	YP_004725079.1. NC_015758.1.
3D structure databases
ProteinModelPortal	F8M7L9.
SMR	F8M7L9. Positions 12-447.
ModBase	Search...
Proteomic databases
PRIDE	F8M7L9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CCC28516; CCC28516; MAF_34470.
GeneID	10956671.
KEGG	maf:MAF_34470.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01580.
Enzyme and pathway databases
BioCyc	MAFR572418:GJCK-3470-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F8M7L9_MYCA0

Accession

Primary (citable) accession number: F8M7L9

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	May 1, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)