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F8M351 (F8M351_MYCA0) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding83 – 875GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding138 – 1414GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
F8M351 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 85F9012F364692FF

FASTA39643,594
        10         20         30         40         50         60 
MAKAKFQRTK PHVNIGTIGH VDHGKTTLTA AITKVLHDKF PDLNETKAFD QIDNAPEERQ 

        70         80         90        100        110        120 
RGITINIAHV EYQTDKRHYA HVDAPGHADY IKNMITGAAQ MDGAILVVAA TDGPMPQTRE 

       130        140        150        160        170        180 
HVLLARQVGV PYILVALNKA DAVDDEELLE LVEMEVRELL AAQEFDEDAP VVRVSALKAL 

       190        200        210        220        230        240 
EGDAKWVASV EELMNAVDES IPDPVRETDK PFLMPVEDVF TITGRGTVVT GRVERGVINV 

       250        260        270        280        290        300 
NEEVEIVGIR PSTTKTTVTG VEMFRKLLDQ GQAGDNVGLL LRGVKREDVE RGQVVTKPGT 

       310        320        330        340        350        360 
TTPHTEFEGQ VYILSKDEGG RHTPFFNNYR PQFYFRTTDV TGVVTLPEGT EMVMPGDNTN 

       370        380        390 
ISVKLIQPVA MDEGLRFAIR EGGRTVGAGR VTKIIK 

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References

[1]"The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex."
Bentley S.D., Comas I., Bryant J.M., Walker D., Smith N.H., Harris S.R., Thurston S., Gagneux S., Wood J., Antonio M., Quail M.A., Gehre F., Adegbola R.A., Parkhill J., de Jong B.C.
PLoS Negl. Trop. Dis. 6:E1552-E1552(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GM041182 EMBL CCC25766.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR878060 Genomic DNA. Translation: CCC25766.1.
RefSeqYP_004722397.1. NC_015758.1.

3D structure databases

ProteinModelPortalF8M351.
SMRF8M351. Positions 5-395.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEF8M351.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC25766; CCC25766; MAF_06940.
GeneID10957460.
KEGGmaf:MAF_06940.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02358.

Enzyme and pathway databases

BioCycMAFR572418:GJCK-699-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8M351_MYCA0
AccessionPrimary (citable) accession number: F8M351
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)