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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus thermophilus JIM 8232
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei603 – 6031UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSTHE1051074:GLLQ-870-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:STH8232_0911Imported
OrganismiStreptococcus thermophilus JIM 8232Imported
Taxonomic identifieri1051074 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000300 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF8LWI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8LWI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFNKLESSN NQEIISEEVG ILKELLDDAT RGIAGEQGLT TIQHLVELYD
60 70 80 90 100
EGDYEALTQA ISEMTNDDMV VASRYFSLLP LLINISEDVD LAYEVNRKNN
110 120 130 140 150
IDESYLGKLS ETFDVVAESD NARDILENVN VVPVLTAHPT QVQRKTMLEL
160 170 180 190 200
TNHIHELLRK HRDVKDGLIN KDKWYADLRR YVEIMMKTDI IREKKLKVKN
210 220 230 240 250
EITNVMEYYN SSLIKAITKL SHEFKRLAVE KGIELDNPTP ITMGMWIGGD
260 270 280 290 300
RDGNPFVTAE TLKLSATLQS EVILNYYIEK VDNLYRSFSL SSRLTEVSET
310 320 330 340 350
VAEMAKLSPD TSVYRENEPY RRAFSYIQSK LIQTLLFFKA GNFSNERAAK
360 370 380 390 400
RLSENVRLGS VSTGEVVADF VHDRLSQSLQ AVSQQTTEFY ETAEAFHDDL
410 420 430 440 450
LAIKNSLLEN DDSVLISGDF EELLQAVEVF GFYLATIDMR QDSSVHEACV
460 470 480 490 500
AELLKSANIV DNYSELTEVE KVAVLLKELQ EDPRTLSSTN VSKSETLEKE
510 520 530 540 550
LAIFRTARLL KDYLGEEVIK QHIISHTESV SDMFELAILL KEVGLVDTER
560 570 580 590 600
ARVQIVPLFE TIEDLENSNE IMKQYLGYDI VKRWIKNSNN YQEIMLGYSD
610 620 630 640 650
SNKDGGYLSS GWTLYKAQNE LTKIGEERGI KITFFHGRGG TVGRGGGPSY
660 670 680 690 700
DAITSQPFGT IKDRIRLTEQ GEVIGNKYGN KDAAYYNLEM LVSATLDRMV
710 720 730 740 750
TRQITDPDEL VDFREIMDSI VQDSNGIYRD LVFGNEHFYD YFFEASPIKE
760 770 780 790 800
VSSLNIGSRP AARKTITDIS GLRAIPWVFS WSQNRIMLPG WYGVGSAFNH
810 820 830 840 850
YIEAEEGNLE KLQHMFETWP FFRSLLSNVD MVLSKSDMNI AFHYAQLAES
860 870 880 890 900
EEVRSVFNII LDEWQLTKNV ILAIEKHDDF LEESPSLKAS LGFRLPYFNV
910 920 930 940
LNYIQIELIK RLRNNNLTDD EISLIHITIN GIATGLRNSG
Length:940
Mass (Da):107,012
Last modified:September 21, 2011 - v1
Checksum:i369DE223D6E0E59A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR875178 Genomic DNA. Translation: CCC19618.1.
RefSeqiWP_011680994.1. NC_017581.1.
YP_006040573.1. NC_017581.1.

Genome annotation databases

EnsemblBacteriaiCCC19618; CCC19618; STH8232_0911.
KEGGistu:STH8232_0911.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR875178 Genomic DNA. Translation: CCC19618.1.
RefSeqiWP_011680994.1. NC_017581.1.
YP_006040573.1. NC_017581.1.

3D structure databases

ProteinModelPortaliF8LWI1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCC19618; CCC19618; STH8232_0911.
KEGGistu:STH8232_0911.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciSTHE1051074:GLLQ-870-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Streptococcus thermophilus strain JIM8232."
    Renault P., Loux V.
    Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JIM 8232Imported.

Entry informationi

Entry nameiF8LWI1_STRTR
AccessioniPrimary (citable) accession number: F8LWI1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 27, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.