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F8KKZ3

- F8KKZ3_STALN

UniProt

F8KKZ3 - F8KKZ3_STALN

Protein

Alanine racemase

Gene

dal

Organism
Staphylococcus lugdunensis (strain N920143)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei30 – 301Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Active sitei257 – 2571Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei304 – 3041Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSLUG1034809:GLKV-1542-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:dalImported
    ORF Names:SLUG_14890Imported
    OrganismiStaphylococcus lugdunensis (strain N920143)Imported
    Taxonomic identifieri1034809 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000011123: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei30 – 301N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF8KKZ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F8KKZ3-1 [UniParc]FASTAAdd to Basket

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    MTATWSVNSD IFFNNVVTVK NNQPIMAVVK NNAYHYGLEY AVNMFLKAGI    50
    NTFSTTSLKE AVRIRKLAPK ATIFLMNAVY DFDIVRHNRI HMTLPSLQYY 100
    YANKSNLYDI NVHLEYENLL HRSGFKNLSE LREVLKDHEQ NNQPHKMHIT 150
    GLWTHFGYAD EFDVPEYDTE KRAWLKVLNT LLAEGYTFDM IHAQNSASFY 200
    REQHQVLSNH THARVGIALY GSRPYSSLKP SEIKQALTVK ANVIQVREVN 250
    KGDYCGYSFA YECKNHHTRL AVVDIGYGDG ILKSRAQHDV IINGKRYPIR 300
    ALMMSHMFVE VDELVHARDE VVLYNNDIRI DEFTFKGVGA NSEQLSAMNH 350
    DSLIKEYK 358
    Length:358
    Mass (Da):41,337
    Last modified:September 21, 2011 - v1
    Checksum:i3FFEB75E478AB135
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR870271 Genomic DNA. Translation: CCB53975.1.
    RefSeqiWP_002478211.1. NC_017353.1.
    YP_005760606.1. NC_017353.1.

    Genome annotation databases

    EnsemblBacteriaiCCB53975; CCB53975; SLUG_14890.
    GeneIDi12426993.
    KEGGisln:SLUG_14890.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR870271 Genomic DNA. Translation: CCB53975.1 .
    RefSeqi WP_002478211.1. NC_017353.1.
    YP_005760606.1. NC_017353.1.

    3D structure databases

    ProteinModelPortali F8KKZ3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCB53975 ; CCB53975 ; SLUG_14890 .
    GeneIDi 12426993.
    KEGGi sln:SLUG_14890.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci SLUG1034809:GLKV-1542-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors."
      Heilbronner S., Holden M.T., van Tonder A., Geoghegan J.A., Foster T.J., Parkhill J., Bentley S.D.
      FEMS Microbiol. Lett. 322:60-67(2011)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: N920143Imported.

    Entry informationi

    Entry nameiF8KKZ3_STALN
    AccessioniPrimary (citable) accession number: F8KKZ3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3