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F8JJ69

- F8JJ69_STREN

UniProt

F8JJ69 - F8JJ69_STREN

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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451SubstrateUniRule annotation
Sitei255 – 2551Critical for catalysisUniRule annotation
Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
Sitei418 – 4181Critical for catalysisUniRule annotation
Binding sitei545 – 5451SubstrateUniRule annotation
Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSCAT1003195:GJCM-6970-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported
Submitted name:
Isocitrate dehydrogenase [NADP]Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:SCAT_p1101Imported, SCATT_p06340Imported
Encoded oniPlasmid pSCATImported
Plasmid pSCATTImported
OrganismiStreptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)Imported
Taxonomic identifieri1003195 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000007842: Plasmid pSCATT

Structurei

3D structure databases

ProteinModelPortaliF8JJ69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

F8JJ69-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDSTIIYTH TDEAPALATY SFLPVVEAYA SKAGVTVETR DISLAGRILA
60 70 80 90 100
VFPEYLEEGQ RIDDALAELG ELAKTPGANI IKLPNISASI PQLKAAVAEL
110 120 130 140 150
REQGYALPEY PDDPKTDEER EIRARYDKVK GSAVNPVLRE GNSDRRAPAS
160 170 180 190 200
VKNYAKTHPH RMGAWTADSK TNVAHMTGDD FRSTEKSAVV AEAGSLRIEL
210 220 230 240 250
AGDDGTTTVL RESVPVLAGE VVDASVMRVA ALREFLAAQV ARAKAEGVLF
260 270 280 290 300
SVHLKATMMK VSDPIVFGHV VRAFFPKTFA KYGEVLASAG LTPNDGLGGI
310 320 330 340 350
FKGLEGLPEG AEIKASFDAE LGEGPALAMV DSDRGITNLH VPSDVIVDAS
360 370 380 390 400
MPAMIRTSGH MWGPDGKEAD TLAVLPDSSY AGVYQAVIDD CRANGAFDPA
410 420 430 440 450
TMGSVPNVGL MAQKAEEYGS HDKTFEIPTT GTVRVVDEAG EVVLQQTVSA
460 470 480 490 500
GDIFRMCQTK DLPVRDWVKL AVTRARATGD PAVFWLDETR AHDAQLITKV
510 520 530 540 550
EAYLAEHDTE GLDIRVMSPV EATKFSLERI RRGENTISVT GNVLRDYLTD
560 570 580 590 600
LFPILELGTS AKMLSIVPLM AGGGLFETGA GGSAPKHVQQ LVKENYLRWD
610 620 630 640 650
SLGEFFALVP SLEQYAKTTG NTRAQVLADT LDRATATFLD EDKSPTRRIG
660 670 680 690 700
GIDNRGSHFY LAMYWAQELA RQTEDAQLAE AFADLARTLT EQESTIVDEL
710 720 730
NAVQGEPADI GGYYKPDPAK AAAVMRPSET FNRAIASLS
Length:739
Mass (Da):79,673
Last modified:September 21, 2011 - v1
Checksum:i7B3C32C5E0D4769C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003229 Genomic DNA. Translation: AEW98827.1.
FQ859184 Genomic DNA. Translation: CCB72125.1.
RefSeqiWP_014151550.1. NC_017585.1.
YP_004920391.1. NC_016113.1.
YP_006050780.1. NC_017585.1.

Genome annotation databases

EnsemblBacteriaiAEW98827; AEW98827; SCATT_p06340.
CCB72125; CCB72125; SCAT_p1101.
GeneIDi11364637.
12645654.
KEGGisct:SCAT_p1101.
scy:SCATT_p06340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003229 Genomic DNA. Translation: AEW98827.1 .
FQ859184 Genomic DNA. Translation: CCB72125.1 .
RefSeqi WP_014151550.1. NC_017585.1.
YP_004920391.1. NC_016113.1.
YP_006050780.1. NC_017585.1.

3D structure databases

ProteinModelPortali F8JJ69.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEW98827 ; AEW98827 ; SCATT_p06340 .
CCB72125 ; CCB72125 ; SCAT_p1101 .
GeneIDi 11364637.
12645654.
KEGGi sct:SCAT_p1101.
scy:SCATT_p06340.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci SCAT1003195:GJCM-6970-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Streptomyces cattleya NRRL 8057, a producer of antibiotics and fluorometabolites."
    Barbe V., Bouzon M., Mangenot S., Badet B., Poulain J., Segurens B., Vallenet D., Marliere P., Weissenbach J.
    J. Bacteriol. 193:5055-5056(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NRRL 8057Imported.
    Plasmid: pSCAT
  2. Genoscope - CEA
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NRRL 8057Imported.
    Plasmid: pSCAT
  3. "Complete genome sequence of Streptomyces cattleya strain DSM 46488."
    Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.
    Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057Imported.
  4. Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.
    Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 46488Imported.
    Plasmid: pSCATT

Entry informationi

Entry nameiF8JJ69_STREN
AccessioniPrimary (citable) accession number: F8JJ69
Secondary accession number(s): G8XH81
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, PlasmidImported, Reference proteomeImported

External Data

Dasty 3