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F8JIN6

- F8JIN6_HYPSM

UniProt

F8JIN6 - F8JIN6_HYPSM

Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Hyphomicrobium sp. (strain MC1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

    Catalytic activityi

    Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation
    Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates.SAAS annotation

    GO - Molecular functioni

    1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
    2. nucleic acid binding Source: InterPro

    Keywords - Molecular functioni

    ExonucleaseUniRule annotationSAAS annotationImported, Hydrolase, Nuclease

    Enzyme and pathway databases

    BioCyciHSP717785:GJ7O-3837-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
    Alternative name(s):
    Exodeoxyribonuclease VII large subunitUniRule annotation
    Gene namesi
    Name:xseAUniRule annotationImported
    Ordered Locus Names:HYPMC_3829Imported
    OrganismiHyphomicrobium sp. (strain MC1)Imported
    Taxonomic identifieri717785 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesHyphomicrobiaceaeHyphomicrobium
    ProteomesiUP000000494: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. exodeoxyribonuclease VII complex Source: InterPro

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Heterooligomer composed of large and small subunits.UniRule annotationSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the XseA family.UniRule annotation

    Phylogenomic databases

    KOiK03601.

    Family and domain databases

    HAMAPiMF_00378. Exonuc_7_L.
    InterProiIPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view]
    PfamiPF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00237. xseA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F8JIN6-1 [UniParc]FASTAAdd to Basket

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    MLAAAGAEKK DIHQVACCNP VVSVASPCSI GGETSKTAKE NGKLLNSIPN    50
    TRESRSGANA PEFSVSELSG AIKRALEEGF GYVRLRGEIS GYRGPHASGH 100
    CYFALKDDKA KIEAVVWKGT FGRLRFKPEE GMEVVAQGKI TTFPGSSKYQ 150
    IVIEALEPAG AGALMALLEE RKRKFAAEGL FDEDRKRPRP FLPKIVGIVT 200
    SPTGAVIRDM LHGFNERFPT RVLLWPVRVQ GEGSAAEVAA AIRGFNALEA 250
    DGTIPRPDVL IVARGGGSLE DLWSFNEEIV VRAVAESTIS LISAVGHETD 300
    WTLIDLVADA RAPTPTKAAE WAVPKYSELI ENVEKLMLRK RTAVRRAIES 350
    ARTHLKASAR GLPKLQDLVA LPRQRFDAAD RRLSRALLAN TRAHATRLAR 400
    VSGRLSPAPI VQKHSRCAER LDGLERRAGR ALLNRVAVSR RVLEGRAALL 450
    KSLGYQSVLS RGFALVRNEA GHMVRQAASL VAGDVLNIEF SDGRVGATVN 500
    GSDVSSATPD VSNPTSSKVK TPRQKSSGRG GQGSLF 536
    Length:536
    Mass (Da):57,739
    Last modified:September 21, 2011 - v1
    Checksum:i698D4A69845AA249
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ859181 Genomic DNA. Translation: CCB67039.1.
    RefSeqiWP_013949432.1. NC_015717.1.
    YP_004677605.1. NC_015717.1.

    Genome annotation databases

    EnsemblBacteriaiCCB67039; CCB67039; HYPMC_3829.
    GeneIDi10892318.
    KEGGihmc:HYPMC_3829.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ859181 Genomic DNA. Translation: CCB67039.1 .
    RefSeqi WP_013949432.1. NC_015717.1.
    YP_004677605.1. NC_015717.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCB67039 ; CCB67039 ; HYPMC_3829 .
    GeneIDi 10892318.
    KEGGi hmc:HYPMC_3829.

    Phylogenomic databases

    KOi K03601.

    Enzyme and pathway databases

    BioCyci HSP717785:GJ7O-3837-MONOMER.

    Family and domain databases

    HAMAPi MF_00378. Exonuc_7_L.
    InterProi IPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view ]
    Pfami PF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00237. xseA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome of Hyphomicrobium sp. MC1."
      Genoscope.
      Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MC1Imported.

    Entry informationi

    Entry nameiF8JIN6_HYPSM
    AccessioniPrimary (citable) accession number: F8JIN6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3