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Protein

Guanylate kinase

Gene

gmk

Organism
Alicyclobacillus acidocaldarius (strain Tc-4-1) (Bacillus acidocaldarius)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.SAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseSAAS annotation (EC:2.7.4.8SAAS annotation)
Gene namesi
Name:gmkImported
Ordered Locus Names:TC41_0085Imported
OrganismiAlicyclobacillus acidocaldarius (strain Tc-4-1) (Bacillus acidocaldarius)Imported
Taxonomic identifieri1048834 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
Proteomesi
  • UP000000292 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1048834.TC41_0085.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 65HTH cro/C1-typeInterPro annotationAdd BLAST56
Domaini78 – 257Guanylate kinase-likeInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
OMAiYGTLKSE.

Family and domain databases

CDDicd00093. HTH_XRE. 1 hit.
InterProiView protein in InterPro
IPR001387. Cro/C1-type_HTH.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR010982. Lambda_DNA-bd_dom.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
PF13443. HTH_26. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50943. HTH_CROC1. 1 hit.

Sequencei

Sequence statusi: Complete.

F8IIA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVSQIRFHL DRLLSERNWK VPDLVKRSGV NKNTLYAMKK NAITRVDLRV
60 70 80 90 100
LERICDALAC KLSDLMTYEP EGETHTKGLL FILSGPSGAG KNTLINALRD
110 120 130 140 150
RYDLGLTFIP SFSTRPMRPG ETNGNPYYFV SREEFMRMAE RGEFLEYETI
160 170 180 190 200
HGNLYGTHLL SYERALNEGR MIIKDIDVNG ALNMKRVFGD RVILIYVRPT
210 220 230 240 250
CLDDLEGRLH HRGDKEEDIR IRMQRLKYEE SLSDQFDFLI FNDDVATATA
260
ELAHIIRTCT RKHA
Length:264
Mass (Da):30,517
Last modified:September 21, 2011 - v1
Checksum:i7B170FEC33F2DAE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002902 Genomic DNA. Translation: AEJ42064.1.

Genome annotation databases

EnsemblBacteriaiAEJ42064; AEJ42064; TC41_0085.
KEGGiaad:TC41_0085.
PATRICifig|1048834.4.peg.77.

Similar proteinsi

Entry informationi

Entry nameiF8IIA5_ALIAT
AccessioniPrimary (citable) accession number: F8IIA5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 25, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported