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Protein

Xylose isomerase

Gene

xylA

Organism
Alicyclobacillus acidocaldarius (strain Tc-4-1) (Bacillus acidocaldarius)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei103UniRule annotation1
Active sitei106UniRule annotation1
Metal bindingi234Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi273Magnesium 2UniRule annotation1
Metal bindingi298Magnesium 1UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi311Magnesium 2UniRule annotation1
Metal bindingi341Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:TC41_2305Imported
OrganismiAlicyclobacillus acidocaldarius (strain Tc-4-1) (Bacillus acidocaldarius)Imported
Taxonomic identifieri1048834 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
Proteomesi
  • UP000000292 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi1048834.TC41_2305

Structurei

3D structure databases

ProteinModelPortaliF8IG53
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini97 – 286AP_endonuc_2InterPro annotationAdd BLAST190

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili114 – 134Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

F8IG53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDVATYFPE VTRIAYEGKG SDNPLCFKYY NPEETVLGKP MKEHLRFSVA
60 70 80 90 100
YWHTFTLSGA DPFGLPNMIR PWDGATGMDL AKRRVEAAFE FMTKLGVEYF
110 120 130 140 150
CFHDRDIAPE GDTLRETNRN LDEIVALIKE YMQSTGIKLL WNTQNLFSNP
160 170 180 190 200
RFAHGAATAP DADVFAYAAA QVKKSLEIAK ELGAENYVFW GGREGYETLL
210 220 230 240 250
NTDLKLELDN YARLLQMAVD YADEIGFTGQ FLIEPKPKEP TKHQYDFDVQ
260 270 280 290 300
SGLAFLYHYG LKDRFKFNIE ANHATLAGHT FQHELRFARI NGLLGSVDAN
310 320 330 340 350
QGDPLLGWDT DEFPTNLYET TLAMYEILLN GGLAPGGLNF DAKVRRASMT
360 370 380 390 400
PIDLFYGHIA GMDSFARGLK VAAKLLEDRV FEREIEERYE SYRAGIGKDI
410 420 430 440
VEGRATLQTL ESYVLDKRVT ATRSGRQEVL LAKLNQYLLE TE
Length:442
Mass (Da):50,105
Last modified:September 21, 2011 - v1
Checksum:i794673C7254F3F13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002902 Genomic DNA Translation: AEJ44206.1

Genome annotation databases

EnsemblBacteriaiAEJ44206; AEJ44206; TC41_2305
KEGGiaad:TC41_2305
PATRICifig|1048834.4.peg.2180

Similar proteinsi

Entry informationi

Entry nameiF8IG53_ALIAT
AccessioniPrimary (citable) accession number: F8IG53
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health