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Protein

Thymidine kinase

Gene

tdk

Organism
Sulfobacillus acidophilus (strain TPY)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkImported
Ordered Locus Names:TPY_2843Imported
OrganismiSulfobacillus acidophilus (strain TPY)Imported
Taxonomic identifieri1051632 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiales Family XVII. Incertae SedisSulfobacillus
Proteomesi
  • UP000000291 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1051632.TPY_2843.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104. Bacteria.
COG1435. LUCA.
KOiK00857.
OMAiCAGLDQD.
OrthoDBiPOG091H0659.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F8I5F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGYITVFTG EMFSGKSEAL EAQVRTAVNR GAVTQVFYPE QAARASQRDI
60 70 80 90 100
AHRLREPHPN LKLTPVPQAD AEWLLRHVVP DADVVAIDEA QFFTPAIVSV
110 120 130 140 150
LQQLRMRGLV IYVAGLDQDY RGNPFGPMGQ ILCIANQIHK LHARCARCGA
160 170 180 190
SEALFSQRVV ALSDQIVIGD TIYQPVCEDC YHLAGAVSLA D
Length:191
Mass (Da):20,946
Last modified:September 21, 2011 - v1
Checksum:i00138A472E8C7B52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002901 Genomic DNA. Translation: AEJ41003.1.

Genome annotation databases

EnsemblBacteriaiAEJ41003; AEJ41003; TPY_2843.
KEGGisay:TPY_2843.
PATRICifig|1051632.5.peg.2759.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF8I5F6_SULAT
AccessioniPrimary (citable) accession number: F8I5F6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: July 5, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported