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Protein

Thymidine kinase

Gene

tdk

Organism
Sulfobacillus acidophilus (strain TPY)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSACI1051632:GH78-2839-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkImported
Ordered Locus Names:TPY_2843Imported
OrganismiSulfobacillus acidophilus (strain TPY)Imported
Taxonomic identifieri1051632 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiales Family XVII. Incertae SedisSulfobacillus
ProteomesiUP000000291 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1051632.TPY_2843.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.
OMAiSTANWSA.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F8I5F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGYITVFTG EMFSGKSEAL EAQVRTAVNR GAVTQVFYPE QAARASQRDI
60 70 80 90 100
AHRLREPHPN LKLTPVPQAD AEWLLRHVVP DADVVAIDEA QFFTPAIVSV
110 120 130 140 150
LQQLRMRGLV IYVAGLDQDY RGNPFGPMGQ ILCIANQIHK LHARCARCGA
160 170 180 190
SEALFSQRVV ALSDQIVIGD TIYQPVCEDC YHLAGAVSLA D
Length:191
Mass (Da):20,946
Last modified:September 21, 2011 - v1
Checksum:i00138A472E8C7B52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002901 Genomic DNA. Translation: AEJ41003.1.
RefSeqiWP_013987719.1. NC_015757.1.
YP_004720746.1. NC_015757.1.

Genome annotation databases

EnsemblBacteriaiAEJ41003; AEJ41003; TPY_2843.
KEGGisay:TPY_2843.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002901 Genomic DNA. Translation: AEJ41003.1.
RefSeqiWP_013987719.1. NC_015757.1.
YP_004720746.1. NC_015757.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1051632.TPY_2843.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEJ41003; AEJ41003; TPY_2843.
KEGGisay:TPY_2843.

Phylogenomic databases

KOiK00857.
OMAiSTANWSA.

Enzyme and pathway databases

BioCyciSACI1051632:GH78-2839-MONOMER.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome analysis of Sulfobacillus acidophilus strain TPY, isolated from a hydrothermal vent in the Pacific ocean."
    Li B., Chen Y., Liu Q., Hu S., Chen X.
    J. Bacteriol. 193:5555-5556(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TPYImported.

Entry informationi

Entry nameiF8I5F6_SULAT
AccessioniPrimary (citable) accession number: F8I5F6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 24, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.