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Protein

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Gene

gpmA

Organism
Leuconostoc sp. (strain C2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei10 – 101Tele-phosphohistidine intermediateUniRule annotation
Binding sitei16 – 1612-phospho-D-glycerateUniRule annotation
Binding sitei61 – 6112-phospho-D-glycerateUniRule annotation
Binding sitei99 – 9912-phospho-D-glycerateUniRule annotation
Active sitei175 – 1751UniRule annotation

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLSP979982:GHM6-79-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Short name:
BPG-dependent PGAMUniRule annotation
Short name:
PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
dPGMUniRule annotation
Gene namesi
Name:gpmAUniRule annotation
Ordered Locus Names:LGMK_00385Imported
OrganismiLeuconostoc sp. (strain C2)Imported
Taxonomic identifieri979982 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000000500: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF8HUB1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 2322-phospho-D-glycerate bindingUniRule annotation
Regioni88 – 9142-phospho-D-glycerate bindingUniRule annotation
Regioni115 – 11622-phospho-D-glycerate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

KOiK01834.
OMAiDNIFTGW.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8HUB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTQLVLVRH GESTANRDNE FTGWTDVPLT LKGRQQAKKV GDILANHQLL
60 70 80 90 100
FDDVHTSYLQ RAITTANIIL LEMNQSWLPV HKTWRLNERH YGALRGLNKD
110 120 130 140 150
AARLKYGVDA VALWRRSYTA VPPLLGKTVT DRRYPDSIEP HGESLQMASE
160 170 180 190 200
RLLPYWSTEI LPGLKAGRNQ LIVAHGSTLR ALIKYLEAIA DDDIDGLEIG
210 220
NGEPICYTFN DQLQLGDRQY LR
Length:222
Mass (Da):25,173
Last modified:September 21, 2011 - v1
Checksum:i173FE8D16AA4FCAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002898 Genomic DNA. Translation: AEJ30141.1.
RefSeqiYP_004704764.1. NC_015734.1.

Genome annotation databases

EnsemblBacteriaiAEJ30141; AEJ30141; LGMK_00385.
GeneIDi10930213.
KEGGilec:LGMK_00385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002898 Genomic DNA. Translation: AEJ30141.1.
RefSeqiYP_004704764.1. NC_015734.1.

3D structure databases

ProteinModelPortaliF8HUB1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEJ30141; AEJ30141; LGMK_00385.
GeneIDi10930213.
KEGGilec:LGMK_00385.

Phylogenomic databases

KOiK01834.
OMAiDNIFTGW.

Enzyme and pathway databases

BioCyciLSP979982:GHM6-79-MONOMER.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Leuconostoc kimchii strain C2, isolated from Kimchi."
    Lee S.H., Jung J.Y., Lee S.H., Jeon C.O.
    J. Bacteriol. 193:5548-5548(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C2Imported.

Entry informationi

Entry nameiF8HUB1_LEUS2
AccessioniPrimary (citable) accession number: F8HUB1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 4, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.