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F8GAQ2 (F8GAQ2_FRAST) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
RNA pyrophosphohydrolase HAMAP-Rule MF_00298

EC=3.6.1.- HAMAP-Rule MF_00298
Alternative name(s):
(Di)nucleoside polyphosphate hydrolase HAMAP-Rule MF_00298
Gene names
Name:rppH HAMAP-Rule MF_00298
Synonyms:nudH HAMAP-Rule MF_00298
Ordered Locus Names:F7308_0660 EMBL AEI35587.1
OrganismFrancisella sp. (strain TX077308) [Complete proteome] [HAMAP] EMBL AEI35587.1
Taxonomic identifier573569 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella

Protein attributes

Sequence length155 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage By similarity. HAMAP-Rule MF_00298 SAAS SAAS022927

Cofactor

Divalent ions By similarity. HAMAP-Rule MF_00298 SAAS SAAS022927

Sequence similarities

Belongs to the Nudix hydrolase family. RppH subfamily. HAMAP-Rule MF_00298

Contains 1 nudix hydrolase domain. HAMAP-Rule MF_00298

Contains nudix hydrolase domain. SAAS SAAS022927

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain6 – 148143Nudix hydrolase By similarity HAMAP-Rule MF_00298
Motif38 – 5922Nudix box By similarity HAMAP-Rule MF_00298

Sequences

Sequence LengthMass (Da)Tools
F8GAQ2 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 13BBBA36DE55CC18

FASTA15518,617
        10         20         30         40         50         60 
MIDKSGYRAN VAIVLLNRQN RVFWGQRKSR TSWQFPQGGV AVGETPLQAM YRELYEEIGL 

        70         80         90        100        110        120 
RPHDVEVIAS TRDWFKYDIP DSLVRSREPV CIGQKQKWFL LRLKTSENNI NLEANDSPEF 

       130        140        150 
DNWRWVSYWY PINHVVYFKQ EVYRKALTYF KEYIN 

« Hide

References

[1]"The complete genome of Francisella sp. TX077308."
Kuske C.R., Challacombe J.F., Siddaramappa S., Petersen J.M.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TX077308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002872 Genomic DNA. Translation: AEI35587.1.
RefSeqYP_004647187.1. NC_015696.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI35587; AEI35587; F7308_0660.
GeneID10861661.
KEGGfrt:F7308_0660.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK08311.

Enzyme and pathway databases

BioCycFSP573569:GHZ6-676-MONOMER.

Family and domain databases

Gene3D3.90.79.10. 1 hit.
HAMAPMF_00298. Nudix_RppH.
InterProIPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR022927. RppH.
[Graphical view]
PfamPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSPR00502. NUDIXFAMILY.
SUPFAMSSF55811. SSF55811. 1 hit.
PROSITEPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8GAQ2_FRAST
AccessionPrimary (citable) accession number: F8GAQ2
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 16, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)