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F8FQ31 (F8FQ31_PAEMK) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlB EMBL AEI39173.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:KNP414_00548 EMBL AEI39173.1
OrganismPaenibacillus mucilaginosus (strain KNP414) [Complete proteome] [HAMAP] EMBL AEI39173.1
Taxonomic identifier1036673 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain177 – 383207ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding210 – 26556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3361Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3501Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3501Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3521Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F8FQ31 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 0522DA17B4C3C9DA

FASTA40244,064
        10         20         30         40         50         60 
MHCFFFLISG TTDFINRRVL MSKIRVGLIY GGKSGEHEVS LQTALAVTKA LDLSKYEVQP 

        70         80         90        100        110        120 
FYITKEGDWR SGPQLTAPAD SVDALTFGSA SSSNETGTFA LQPLFGSSAA AKASGNPAVS 

       130        140        150        160        170        180 
GSESGAAAGP LDVVLPLLHG TFGEDGTVQG LLEMANIAYV GTGVLASAVG MDKVMMKKVF 

       190        200        210        220        230        240 
AQEGLPQCVF RHFTKSQWEK DNAFFIMEIE VAIGYPCFVK PANLGSSVGI NKARNRDELL 

       250        260        270        280        290        300 
SAIAEAFRYD RKVIVEEFID ARELEVAVLG NDEPQASVVG EIVSSGEFYD YKAKYIDGKS 

       310        320        330        340        350        360 
SMIIPAEIDS EQASRIRDLA VRAFQSIDGT GLSRVDFFLR KDNGEIYINE INTMPGFTPF 

       370        380        390        400 
SMYPLLWRES GKPYSELLDD LVRLAIQRHE EKQRLQYSFD LT 

« Hide

References

[1]"Complete genome sequence of Paenibacillus mucilaginosus KNP414."
Wang J., Hu S., Hu X., Zhang B., Dong D., Zhang S., Zhao K., Wu D.
Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KNP414.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002869 Genomic DNA. Translation: AEI39173.1.
RefSeqYP_004639043.1. NC_015690.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI39173; AEI39173; KNP414_00548.
GeneID10853427.
KEGGpms:KNP414_00548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.
OMAMDKIAMK.

Enzyme and pathway databases

BioCycPMUC1036673:GJD1-548-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8FQ31_PAEMK
AccessionPrimary (citable) accession number: F8FQ31
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 19, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)