F8F7I9 (F8F7I9_PAEMK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-aminoethylphosphonate--pyruvate transaminase HAMAP-Rule MF_01376
EC=2.6.1.37 HAMAP-Rule MF_01376

Alternative name(s):
2-aminoethylphosphonate aminotransferase HAMAP-Rule MF_01376
AEP transaminase HAMAP-Rule MF_01376

Gene names

Name:	phnW HAMAP-Rule MF_01376 EMBL AEI39474.1
Ordered Locus Names:	KNP414_00884 EMBL AEI39474.1

Organism

Paenibacillus mucilaginosus (strain KNP414) [Complete proteome] [HAMAP]

Taxonomic identifier

1036673 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus › Paenibacillus mucilaginosus

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in phosphonate degradation By similarity. HAMAP-Rule MF_01376 SAAS SAAS012703
Catalytic activity	(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine. HAMAP-Rule MF_01376 SAAS SAAS012703
Cofactor	Pyridoxal phosphate By similarity. HAMAP-Rule MF_01376
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_01376
Sequence similarities	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. HAMAP-Rule MF_01376

Ontologies

Keywords
Ligand	Pyridoxal phosphate HAMAP-Rule MF_01376 SAAS SAAS012703 Pyruvate HAMAP-Rule MF_01376 SAAS SAAS012703
Molecular function	Aminotransferase HAMAP-Rule MF_01376 SAAS SAAS012703 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	organic phosphonate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	2-aminoethylphosphonate-pyruvate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	215	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01376

Sequences

	Sequence		Length	Mass (Da)
	F8F7I9 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: 86B6F5C6BF1FF53F	FASTA	403	43,926
	10 20 30 40 50 60 MMRAGNPGDA VRLPGGEADL PEAPYLLLTP GPLTTTKTVK ASMLRDWCTW DRDYNGLVQS 70 80 90 100 110 120 VRERLVELAA PGGAREFTAV LMQGSGTFAV ESAVGTFLPR EGGKLAVLCN GAYGERIARI 130 140 150 160 170 180 AEVLGIELAL LRSEETEPAD AEALARLLEA DPAITHVAAV HCETTTGMLN PVRDIAAAAK 190 200 210 220 230 240 RYGRTVIIDA MSSFGGIPLD MQELGIDVLV SSSNKCIQGV PGFGFVIARR ELLAGCRGHA 250 260 270 280 290 300 RSHALDLFDQ WETMERHGGK WRFTSPTHVV RAFDQALQEL EAEGGPAARH ARYLESHRTL 310 320 330 340 350 360 VDGMEALGFL PLLPEALRSP FITTFRYPAS AGFDFGEWYL RLKAAGFVIY PGKLSSADTF 370 380 390 400 RIGTIGEVYP EDMRRLTEAV KRSRFWLEAG ASEEDVPEHS PVR

References

[1]	"Complete genome sequence of Paenibacillus mucilaginosus KNP414." Wang J., Hu S., Hu X., Zhang B., Dong D., Zhang S., Zhao K., Wu D. Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KNP414 EMBL AEI39474.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002869 Genomic DNA. Translation: AEI39474.1.
RefSeq	YP_004639344.1. NC_015690.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEI39474; AEI39474; KNP414_00884.
GeneID	10853763.
KEGG	pms:KNP414_00884.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03430.
Enzyme and pathway databases
BioCyc	PMUC1036673:GJD1-884-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
HAMAP	MF_01376. PhnW_aminotrans_5.
InterPro	IPR000192. Aminotrans_V/Cys_dSase. IPR012703. NH2EtPonate_pyrv_transaminase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR024169. SP_NH2Trfase/AEP_transaminase. [Graphical view]
PANTHER	PTHR21152:SF6. PTHR21152:SF6. 1 hit.
Pfam	PF00266. Aminotran_5. 1 hit. [Graphical view]
PIRSF	PIRSF000524. SPT. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR03301. PhnW-AepZ. 1 hit. TIGR02326. transamin_PhnW. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F8F7I9_PAEMK

Accession

Primary (citable) accession number: F8F7I9

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)