ID   F8F2T3_GRAC1            Unreviewed;       432 AA.
AC   F8F2T3;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=phosphoenolpyruvate mutase {ECO:0000256|ARBA:ARBA00024063};
DE            EC=5.4.2.9 {ECO:0000256|ARBA:ARBA00024063};
GN   OrderedLocusNames=Spica_1331 {ECO:0000313|EMBL:AEJ19477.1};
OS   Gracilinema caldarium (strain ATCC 51460 / DSM 7334 / H1) (Treponema
OS   caldarium).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Breznakiellaceae;
OC   Gracilinema.
OX   NCBI_TaxID=744872 {ECO:0000313|EMBL:AEJ19477.1, ECO:0000313|Proteomes:UP000000503};
RN   [1] {ECO:0000313|Proteomes:UP000000503}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 51460 / DSM 7334 / H1 {ECO:0000313|Proteomes:UP000000503};
RX   PubMed=23961314; DOI=10.4056/sigs.3096473;
RA   Abt B., Goker M., Scheuner C., Han C., Lu M., Misra M., Lapidus A.,
RA   Nolan M., Lucas S., Hammon N., Deshpande S., Cheng J.F., Tapia R.,
RA   Goodwin L.A., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA   Mikhailova N., Huntemann M., Pati A., Chen A., Palaniappan K., Land M.,
RA   Hauser L., Jeffries C.D., Rohde M., Spring S., Gronow S., Detter J.C.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Woyke T., Klenk H.P.;
RT   "Genome sequence of the thermophilic fresh-water bacterium Spirochaeta
RT   caldaria type strain (H1(T)), reclassification of Spirochaeta caldaria,
RT   Spirochaeta stenostrepta, and Spirochaeta zuelzerae in the genus Treponema
RT   as Treponema caldaria comb. nov., Treponema stenostrepta comb. nov., and
RT   Treponema zuelzerae comb. nov., and emendation of the genus Treponema.";
RL   Stand. Genomic Sci. 8:88-105(2013).
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DR   EMBL; CP002868; AEJ19477.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8F2T3; -.
DR   STRING; 744872.Spica_1331; -.
DR   KEGG; scd:Spica_1331; -.
DR   eggNOG; COG0615; Bacteria.
DR   eggNOG; COG2513; Bacteria.
DR   HOGENOM; CLU_027389_0_1_12; -.
DR   Proteomes; UP000000503; Chromosome.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0050188; F:phosphoenolpyruvate mutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd02170; cytidylyltransferase; 1.
DR   CDD; cd00377; ICL_PEPM; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR039556; ICL/PEPM.
DR   InterPro; IPR012698; PEnolPyrv_PMutase_core.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR   NCBIfam; TIGR02320; PEP_mutase; 1.
DR   PANTHER; PTHR43793; FAD SYNTHASE; 1.
DR   PANTHER; PTHR43793:SF1; FAD SYNTHASE; 1.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   Pfam; PF13714; PEP_mutase; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AEJ19477.1};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000503};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          11..104
FT                   /note="Cytidyltransferase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01467"
SQ   SEQUENCE   432 AA;  48062 MW;  DDAB1181595B6F5E CRC64;
     MPIVYLGMIG DIIHPGIVNI VREASKHGDV LVGLFTDKAI ASHKRLPYLS YEQRREVVEN
     LKGVSRVVPQ DEWSYVPNLR KYRPDFIIHG DDWKNGPESS LREEVFAVMA ELGGSVIEIP
     YTKGINSSAL NESLKAIGTT PEIRMKTLRR LLAAKPIVRV LEAHSGLSGL IVENIEFEAP
     DGKRFFDAMW SSSLTDSTVK GKPDIEAVDL TSRLQNLTDI LECTTKPIIF DGDTGGLEEH
     FVFTVRTLER HGVSAVIIED KVGLKKNSLF GTEVKQELAP IDEFCSKISA GKRAQVTKDF
     MIIARIESLI AGRDVNEALT RARSYVAAGA DGIMIHSKEK SGNDIKEFCL SFRKDYPHVP
     LVLVPTTYNR FTEDELASWG ASIIIYANHL LRASYPAMVK AAELILANKR SLEADEICMP
     IKEILELIPE TK
//