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Protein

Elongation factor Tu

Gene

tuf

Organism
Flexistipes sinusarabici (strain DSM 4947 / MAS 10)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Flexsi_0449Imported, Flexsi_0462Imported
OrganismiFlexistipes sinusarabici (strain DSM 4947 / MAS 10)Imported
Taxonomic identifieri717231 [NCBI]
Taxonomic lineageiBacteriaDeferribacteresDeferribacteralesDeferribacteraceaeFlexistipes
Proteomesi
  • UP000006621 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi717231.Flexsi_0462.

Structurei

3D structure databases

ProteinModelPortaliF8E997.
SMRiF8E997.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
KOiK02358.
OMAiYGHIDCP.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel_sf.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F8E997-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQKYERKK PHVNVGTIGH VDHGKTTLTA AMTHVLSLKG YADYIEFGNI
60 70 80 90 100
DKAPEEKERG ITIATAHVEY ESDKRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHI LLARQVGVPS IVVFMNKCDM VDDEELLELV
160 170 180 190 200
ELEIRDLLNT YEFPGDDIPI IKGSALQALE NAEDEEKTKC IWELLQAMDD
210 220 230 240 250
YIPAPERDID KPFLMPIEDV FSISGRGTVV TGRVERGKVR VQDEIEIVGL
260 270 280 290 300
TDTRKTVVTG VEMFRKILDE GEAGDNVGVL LRGIKKDDVE RGQVLAKPGS
310 320 330 340 350
ITPHRKFKCE AYILTKEEGG RHTPFFSGYR PQFYFRTTDV TGVITLAEGV
360 370 380 390
EMVMPGDNIS CDVDLIQPIA MEQGLRFAIR EGGRTVGAGV VTEIVE
Length:396
Mass (Da):43,900
Last modified:September 21, 2011 - v1
Checksum:iA9732FCE180EA5A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002858 Genomic DNA. Translation: AEI14136.1.
CP002858 Genomic DNA. Translation: AEI14149.1.
RefSeqiWP_013885646.1. NC_015672.1.

Genome annotation databases

EnsemblBacteriaiAEI14136; AEI14136; Flexsi_0449.
AEI14149; AEI14149; Flexsi_0462.
KEGGifsi:Flexsi_0449.
fsi:Flexsi_0462.

Similar proteinsi

Entry informationi

Entry nameiF8E997_FLESM
AccessioniPrimary (citable) accession number: F8E997
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported