ID   F8E8Z5_FLESM            Unreviewed;       291 AA.
AC   F8E8Z5;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=DNA polymerase LigD, polymerase domain protein {ECO:0000313|EMBL:AEI14119.1};
GN   OrderedLocusNames=Flexsi_0431 {ECO:0000313|EMBL:AEI14119.1};
OS   Flexistipes sinusarabici (strain ATCC 49648 / DSM 4947 / MAS 10).
OC   Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC   Flexistipitaceae; Flexistipes.
OX   NCBI_TaxID=717231 {ECO:0000313|EMBL:AEI14119.1, ECO:0000313|Proteomes:UP000006621};
RN   [1] {ECO:0000313|EMBL:AEI14119.1, ECO:0000313|Proteomes:UP000006621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RX   PubMed=22180813; DOI=10.4056/sigs.2235024;
RA   Lapidus A., Chertkov O., Nolan M., Lucas S., Hammon N., Deshpande S.,
RA   Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA   Abt B., Spring S., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Woyke T.;
RT   "Genome sequence of the moderately thermophilic halophile Flexistipes
RT   sinusarabici strain (MAS10).";
RL   Stand. Genomic Sci. 5:86-96(2011).
RN   [2] {ECO:0000313|Proteomes:UP000006621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Chertkov O.,
RA   Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Flexistipes sinusarabici DSM 4947.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002858; AEI14119.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8E8Z5; -.
DR   STRING; 717231.Flexsi_0431; -.
DR   KEGG; fsi:Flexsi_0431; -.
DR   eggNOG; COG3285; Bacteria.
DR   HOGENOM; CLU_008325_1_1_0; -.
DR   Proteomes; UP000006621; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd04861; LigD_Pol_like; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006621}.
FT   DOMAIN          26..279
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
SQ   SEQUENCE   291 AA;  34510 MW;  51897A7E4A4F8082 CRC64;
     MKQKINGRTI EISNPHKVFY PNANITKGEI LNYYNRIAEY MLPHIRNRLV VMQRFPEGIG
     KEGFYHKQVP DYFPEWLQRK TVTLRKGEKQ DIAVVNKKAD IIYMAEKGVI TFHIWLSQKD
     NIEKPDKLIF DLDPPKKGEF SEVKFAAYKL RDLFQDMGLI PYVMTTGSKG VHVVTPIKPE
     YDFDIIRQYV RDILTELVKK YPDRFTLEPR KDERQGRVFL DYLRHAFGQT SVAPYSLRPI
     EGAPIATLLE WEELPYIENS QKYHMKNIFK RLSQKKDPWK EFKLHRKSLD I
//