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F8E1W3 (F8E1W3_CORRG) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2811Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1481Substrate By similarity HAMAP-Rule MF_01201
Binding site3291Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue441N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F8E1W3 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: A6BA8CD311A5C523

FASTA55959,434
        10         20         30         40         50         60 
MYQPLPVPAE HALAEVIIDL SAVRSNVSLF ADAAPSAEVM AVVKADAYNH GAFSVARACL 

        70         80         90        100        110        120 
ESGATQLGVA TIGEALSLRT AGITAPITAW MWIPGEDLSR AIQQDITIGV PSLAHAEALV 

       130        140        150        160        170        180 
ELVDTLEQSD SNSTPIAISL MADTGLSRSG ITPDQWATVV ELIAKYSASF DVRGVMSHLA 

       190        200        210        220        230        240 
SADDSARAAF TDVQNRRFQR AIEICREHGI DPRTNHIANT PAALTRPDLH HQMVRPGVGI 

       250        260        270        280        290        300 
YGIDPVVGGS GGNAGQLRPA ITFRAKVITT KTIRAGESVS YGGTWTATRD TRTAVVAAGY 

       310        320        330        340        350        360 
ADGVPRAASG KFHVGIGGKL YPQIGRVCMD QIVVNLGDSE EPTDVKPGDW ATIFGEGGIS 

       370        380        390        400        410        420 
ASELAAAAET IDYEILTMPR GPRVWRRWVG EEKEQLDLSH SNGHATASTS EDMVEAGRRI 

       430        440        450        460        470        480 
GEQLEAGTVV VLTGPLGAGK TTLTQGLAAG LEVKGRVQSP TFTIVRTHKP SGSGRPGMLH 

       490        500        510        520        530        540 
MDAYRLLGAD VSEGVEPGKH VDRDVVLDAL ESLDIDSDLD QVVVIAEWGR GVVETLSDKV 

       550 
LDIEIDRAAD ERILRWEWK 

« Hide

References

[1]"Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient."
Schroder J., Maus I., Meyer K., Wordemann S., Blom J., Jaenicke S., Schneider J., Trost E., Tauch A.
BMC Genomics 13:141-141(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 45100 / JCM 12819 / GTC 2026.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002857 Genomic DNA. Translation: AEI10176.1.
RefSeqYP_004606340.1. NC_015673.1.

3D structure databases

ProteinModelPortalF8E1W3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI10176; AEI10176; CRES_1823.
GeneID10818552.
KEGGcrd:CRES_1823.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMANFFVAHI.

Enzyme and pathway databases

BioCycCRES662755:GIVW-1860-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR027417. P-loop_NTPase.
IPR029066. PLP-binding_barrel.
IPR003442. T6A_TsaE.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF02367. UPF0079. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
TIGR00150. T6A_YjeE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF8E1W3_CORRG
AccessionPrimary (citable) accession number: F8E1W3
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: July 9, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)