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F8E0G8

- F8E0G8_CORRG

UniProt

F8E0G8 - F8E0G8_CORRG

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Protein

Glutaminase

Gene
glsA, CRES_0853
Organism
Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei86 – 861Substrate By similarityUniRule annotation
Binding sitei136 – 1361Substrate By similarityUniRule annotation
Binding sitei182 – 1821Substrate By similarityUniRule annotation
Binding sitei189 – 1891Substrate By similarityUniRule annotation
Binding sitei213 – 2131Substrate By similarityUniRule annotation
Binding sitei265 – 2651Substrate By similarityUniRule annotation
Binding sitei283 – 2831Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotationsImported

Enzyme and pathway databases

BioCyciCRES662755:GIVW-873-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotationImported
Ordered Locus Names:CRES_0853Imported
OrganismiCorynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026)Imported
Taxonomic identifieri662755 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000492: Chromosome

PTM / Processingi

Keywords - PTMi

AcetylationUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliF8E0G8.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

KOiK01425.
OMAiLEHAHRN.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
SSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8E0G8-1 [UniParc]FASTAAdd to Basket

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MQLNTPERKL VKEGLISDYL RSIMADNADN SEGQTAQYIA ALRDADPEPF    50
ATALCTLDGR IYSSAYGGSF TDANVAADQV EFTIQSISKP FVYALALEEH 100
GIEELMKVVG MEPSGEAFNE LSLEGDTKRP VNPMINAGAI TVNQLINGSE 150
SSVEDRVAKI HDFMNELAGR KLMLDKQTAS SELESSDRNL ALAHMLRSYH 200
IIQDSAEDAV NSYVQQCSIK VNVRDLAVMG ATLASGGVQP LTGKRVMKQS 250
VARQVQSVMA SAGMYNAAGR WMARVGIPAK SGVAGGVLGT LPGQLGLSSF 300
SPKLDEQGNS VRGVRVFQRL SKDMGLHLMA PEPRGRASVR SLTEDESTGE 350
SIVCLQGDID FIGGERLYRT LMEHQLKHKQ LVFDLTRVDG MNSVGRKMLT 400
NGIELLREEG FSIRIEDPDG LLA 423
Length:423
Mass (Da):45,900
Last modified:September 21, 2011 - v1
Checksum:i6E507FE39BC25BCA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002857 Genomic DNA. Translation: AEI09209.1.
RefSeqiWP_013888226.1. NC_015673.1.
YP_004605373.1. NC_015673.1.

Genome annotation databases

EnsemblBacteriaiAEI09209; AEI09209; CRES_0853.
GeneIDi10817565.
KEGGicrd:CRES_0853.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002857 Genomic DNA. Translation: AEI09209.1 .
RefSeqi WP_013888226.1. NC_015673.1.
YP_004605373.1. NC_015673.1.

3D structure databases

ProteinModelPortali F8E0G8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEI09209 ; AEI09209 ; CRES_0853 .
GeneIDi 10817565.
KEGGi crd:CRES_0853.

Phylogenomic databases

KOi K01425.
OMAi LEHAHRN.

Enzyme and pathway databases

BioCyci CRES662755:GIVW-873-MONOMER.

Family and domain databases

Gene3Di 3.30.750.24. 1 hit.
3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
IPR002645. STAS_dom.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF52091. SSF52091. 1 hit.
SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
PROSITEi PS50801. STAS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient."
    Schroder J., Maus I., Meyer K., Wordemann S., Blom J., Jaenicke S., Schneider J., Trost E., Tauch A.
    BMC Genomics 13:141-141(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 45100 / JCM 12819 / GTC 2026.

Entry informationi

Entry nameiF8E0G8_CORRG
AccessioniPrimary (citable) accession number: F8E0G8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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