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F8DVG5 (SCR_ZYMMA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sucrose-6-phosphate hydrolase

Short name=Sucrase
EC=3.2.1.26
Alternative name(s):
Invertase
Gene names
Name:sacA
Synonyms:invA
Ordered Locus Names:Zmob_0361
OrganismZymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1) [Complete proteome] [HAMAP]
Taxonomic identifier555217 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.

Pathway

Glycan biosynthesis; sucrose metabolism.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 32 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processsucrose metabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsucrose alpha-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 512512Sucrose-6-phosphate hydrolase
PRO_0000414237

Regions

Region40 – 434Substrate binding By similarity
Region102 – 1032Substrate binding By similarity
Region165 – 1662Substrate binding By similarity

Sites

Active site431 By similarity
Binding site591Substrate By similarity
Binding site671Substrate By similarity
Binding site2291Substrate By similarity
Binding site3111Substrate By similarity

Experimental info

Sequence conflict391G → S in AAA27701. Ref.1
Sequence conflict295 – 2973FEA → LKL in AAA27701. Ref.1
Sequence conflict303 – 3086ILIAWF → NINCMV in AAA27701. Ref.1
Sequence conflict312 – 3143ENQ → KS in AAA27701. Ref.1

Sequences

Sequence LengthMass (Da)Tools
F8DVG5 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: E36934E9797C6DC9

FASTA51258,586
        10         20         30         40         50         60 
MESPSYKNLI KAEDAQKKAG KRLLSSEWYP GFHVTPLTGW MNDPNGLIFF KGEYHLFYQY 

        70         80         90        100        110        120 
YPFAPVWGPM HWGHAKSRDL VHWETLPVAL APGDSFDRDG CFSGCAVDNN GVLTLIYTGH 

       130        140        150        160        170        180 
IVLSNDSPDA IREVQCMATS IDGIHFQKEG IVLEKAPMPQ VAHFRDPRVW KENDHWFMVV 

       190        200        210        220        230        240 
GYRTDDKKHQ GIGHVALYRS ENLKDWIFVK TLLGDNSQLP LGKRAFMWEC PDFFSLGNRS 

       250        260        270        280        290        300 
VLMFSPQGLK ASGYKNRNLF QNGYILGKWQ APQFTPETSF QELDYGHDFY AAQRFEAKDG 

       310        320        330        340        350        360 
RQILIAWFDM WENQKPSQRD GWAGCMTLPR KLDLIDNKIV MTPVREMEIL RQSEKIESVV 

       370        380        390        400        410        420 
TLSDAEHPFT MDSPLQEIEL IFDLEKSNAY QAGLALRCNG KGQETLLYID RSQNRIILDR 

       430        440        450        460        470        480 
NRSGQNVKGI RSCPLPNTSK VRLHIFLDRS SIEIFVGDDQ TQGLYSISSR IFPDKDSLKG 

       490        500        510 
RLFAIEGYAV FDSFKRWTLQ DANLAAFSSD AC 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and sequencing of the sacA gene: characterization of a sucrase from Zymomonas mobilis."
Gunasekaran P., Karunakaran T., Cami B., Mukundan A.G., Preziosi L., Baratti J.
J. Bacteriol. 172:6727-6735(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1.
[2]"Genome sequence of the ethanol-producing Zymomonas mobilis subsp. mobilis lectotype strain ATCC 10988."
Pappas K.M., Kouvelis V.N., Saunders E., Brettin T.S., Bruce D., Detter C., Balakireva M., Han C.S., Savvakis G., Kyrpides N.C., Typas M.A.
J. Bacteriol. 193:5051-5052(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M62718 Genomic DNA. Translation: AAA27701.1.
CP002850 Genomic DNA. Translation: AEH62209.1.
PIRA37803.
RefSeqYP_005620660.1. NC_017262.1.

3D structure databases

ProteinModelPortalF8DVG5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH62209; AEH62209; Zmob_0361.
GeneID12281431.
KEGGzmm:Zmob_0361.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01193.
OMAGHAKSAD.

Enzyme and pathway databases

BioCycZMOB555217:GLMZ-376-MONOMER.
UniPathwayUPA00238.

Family and domain databases

Gene3D2.115.10.20. 1 hit.
2.60.120.560. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
IPR023296. Glyco_hydro_beta-prop.
IPR006232. Suc6P_hydrolase.
[Graphical view]
PfamPF08244. Glyco_hydro_32C. 1 hit.
PF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTSM00640. Glyco_32. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
SSF75005. SSF75005. 1 hit.
TIGRFAMsTIGR01322. scrB_fam. 1 hit.
PROSITEPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCR_ZYMMA
AccessionPrimary (citable) accession number: F8DVG5
Secondary accession number(s): P22632 expand/collapse secondary AC list , P35636, Q5NNZ4, Q84CM3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: September 21, 2011
Last modified: October 16, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries