F8DRV7 (F8DRV7_LACRS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP-Rule MF_01039
Short name=BPG-dependent PGAM HAMAP-Rule MF_01039
Short name=PGAM HAMAP-Rule MF_01039
Short name=Phosphoglyceromutase HAMAP-Rule MF_01039
Short name=dPGM HAMAP-Rule MF_01039
EC=5.4.2.1 HAMAP-Rule MF_01039

Gene names

Name:	gpm2 EMBL AEI57509.1
Synonyms:	gpmA HAMAP-Rule MF_01039
Ordered Locus Names:	HMPREF0538_21299 EMBL AEI57509.1

Organism

Lactobacillus reuteri (strain ATCC 55730 / SD2112) [Complete proteome] [HAMAP] EMBL AEI57509.1

Taxonomic identifier

491077 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus reuteri

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01039 RuleBase RU004512 SAAS SAAS013078
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP-Rule MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP-Rule MF_01039 SAAS SAAS013078
Molecular function	Isomerase HAMAP-Rule MF_01039 SAAS SAAS013078 EMBL AEI57509.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular_function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP-Rule MF_01039
	Active site	182	1	By similarity HAMAP-Rule MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP-Rule MF_01039

Sequences

	Sequence		Length	Mass (Da)
	F8DRV7 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: 713FD0E21EDF9222	FASTA	228	26,122
	10 20 30 40 50 60 MAKLVLIRHG QSEWNLSNQF TGWVDVDLSE KGVEQAKNAG KALKEHGIEF DYAYTSVLKR 70 80 90 100 110 120 AIKTLHYALE ECDQLWIPEY KTWRLNERHY GALQGHNKQK AAEKYGDEQV HIWRRSYDVL 130 140 150 160 170 180 PPLLSADDEG SAAKDRRYAN LDPRAIPGGE NLKVTLERVI PLWQDEIAPK LLDNKNVIIA 190 200 210 220 AHGNSLRALS KYIENISDED IMNLEMATGQ PVVYDFDDKL NVLSKEKY

References

[1]

"The complete genome of Lactobacillus reuteri ATCC 55730 / SD2112." Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A., Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X., Perez L., Shen H., Wang Q., Watt J. , Xi L., Xin Y., Zhou J., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A., Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B., Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R. Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 55730 / SD2112.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002844 Genomic DNA. Translation: AEI57509.1.
RefSeq	YP_004649799.1. NC_015697.1.
3D structure databases
ProteinModelPortal	F8DRV7.
SMR	F8DRV7. Positions 1-225.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEI57509; AEI57509; HMPREF0538_21299.
GeneID	10867345.
KEGG	lru:HMPREF0538_21299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01834.
Enzyme and pathway databases
BioCyc	LREU491077:GH1M-1401-MONOMER.
UniPathway	UPA00109; UER00186.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA.
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
PANTHER	PTHR11931. PTHR11931. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F8DRV7_LACRS

Accession

Primary (citable) accession number: F8DRV7

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)