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F8DNX1 (F8DNX1_LACRS) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Trigger factor HAMAP-Rule MF_00303

Short name=TF HAMAP-Rule MF_00303
EC=5.2.1.8 HAMAP-Rule MF_00303
Alternative name(s):
PPIase HAMAP-Rule MF_00303
Gene names
Name:tig HAMAP-Rule MF_00303 EMBL AEI58107.1
Ordered Locus Names:HMPREF0538_21899 EMBL AEI58107.1
OrganismLactobacillus reuteri (strain ATCC 55730 / SD2112) [Complete proteome] [HAMAP] EMBL AEI58107.1
Taxonomic identifier491077 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation By similarity. RuleBase RU003914

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase By similarity. HAMAP-Rule MF_00303

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0). HAMAP-Rule MF_00303

Subcellular location

Cytoplasm. Note: About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm By similarity. HAMAP-Rule MF_00303

Domain

Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own By similarity. HAMAP-Rule MF_00303

Sequence similarities

Belongs to the FKBP-type PPIase family. Tig subfamily. HAMAP-Rule MF_00303 RuleBase RU003914

Contains 1 PPIase FKBP-type domain. HAMAP-Rule MF_00303

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain164 – 24683PPIase FKBP-type By similarity HAMAP-Rule MF_00303

Sequences

Sequence LengthMass (Da)Tools
F8DNX1 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: EF02E138E3915441

FASTA43648,747
        10         20         30         40         50         60 
MSAKWERDSD ASKGTLTFEI DVDTINKGID EAFVETRKKI TVPGFRKGRV PRQIFNQMYG 

        70         80         90        100        110        120 
EESLYQDALN KVLPDAYNEA VKETNIQPVD QPKIDIKSME KGQPWVLTAE VDVMPEVKLG 

       130        140        150        160        170        180 
EYKGMEVPAQ DTTVTDADVD DALETKRQQQ AELVLKEDKP AEKGDTVVID YKGSVDGEEF 

       190        200        210        220        230        240 
DGGSAENYSL ELGSGSFIPG FEDQLIGHNA DEDVDVNVTF PEDYHAKNLA GKDALFKVKI 

       250        260        270        280        290        300 
HEIKEKQLPE LDDDFAKDVD EDVDTLAELK EKTKKQLQEE KDNQAKAAIE DAAINKAVAN 

       310        320        330        340        350        360 
AEIQDIPQAM LDDDTNRQMQ QYLAGMQQQG ISPQMYFQIT GTKEEDLKKQ FANDAAQRVK 

       370        380        390        400        410        420 
TNLVLEAIVD DANLDATDEE IAKEISDLAK QYGMEEDAVK KALSKDMLMH DIKIRKAVDL 

       430 
VADSAKQVKD DEKSDK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002844 Genomic DNA. Translation: AEI58107.1.
RefSeqYP_004650397.1. NC_015697.1.

3D structure databases

ProteinModelPortalF8DNX1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI58107; AEI58107; HMPREF0538_21899.
GeneID10868004.
KEGGlru:HMPREF0538_21899.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03545.
OMAKMAMIED.
OrthoDBEOG63VBX3.

Enzyme and pathway databases

BioCycLREU491077:GH1M-2006-MONOMER.

Family and domain databases

Gene3D1.10.3120.10. 1 hit.
3.30.70.1050. 1 hit.
HAMAPMF_00303. Trigger_factor_Tig.
InterProIPR001179. PPIase_FKBP_dom.
IPR005215. Trig_fac.
IPR008880. Trigger_fac_C.
IPR008881. Trigger_fac_ribosome-bd_bac.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view]
PfamPF00254. FKBP_C. 1 hit.
PF05698. Trigger_C. 1 hit.
PF05697. Trigger_N. 1 hit.
[Graphical view]
PIRSFPIRSF003095. Trigger_factor. 1 hit.
SUPFAMSSF102735. SSF102735. 1 hit.
SSF109998. SSF109998. 1 hit.
TIGRFAMsTIGR00115. tig. 1 hit.
PROSITEPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8DNX1_LACRS
AccessionPrimary (citable) accession number: F8DNX1
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 16, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)