F8DL25 (F8DL25_LACRS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	ala EMBL AEI57644.1
Ordered Locus Names:	HMPREF0538_21434 EMBL AEI57644.1

Organism

Lactobacillus reuteri (strain ATCC 55730 / SD2112) [Complete proteome] [HAMAP] EMBL AEI57644.1

Taxonomic identifier

491077 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus reuteri

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL AEI57644.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F8DL25 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: 8C070DDEBC68098C	FASTA	375	41,270
	10 20 30 40 50 60 MVNGRLRDTS LIVDLDALRH NIQEQRKVLP ENSRILAVVK ANAYGNGLIP VAQTAMTSGA 70 80 90 100 110 120 SGLCVAILDE ALELWDNGIE AMTLVLGITP VEDALIAAQA GVSLTVGSLD WLEQYHQLAQ 130 140 150 160 170 180 VAKPKKPLKV HLGIDSGMGR IGFTEVATFK QAVKLLDSPE FEFEGMFTHF ATADSPDENY 190 200 210 220 230 240 FNQQVQRWHQ FVASLDELPP YVHMANSATG LWHREKITAN TVRMGISMYG QNPSGRDLKL 250 260 270 280 290 300 TLDLQPVSSL VSSISFVKQL KAGRSVSYGA TYTAEQDEWL ATLPIGYADG YPRCMTGYKV 310 320 330 340 350 360 LVDGQFCDIA GRVCMDQMMI QLPKYYPVGT PVVLMGKSGD QEITATDLAE QAGTINYEIL 370 TNISNRVHRI YHQSK

References

[1]

"The complete genome of Lactobacillus reuteri ATCC 55730 / SD2112." Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A., Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X., Perez L., Shen H., Wang Q., Watt J. , Xi L., Xin Y., Zhou J., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A., Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B., Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R. Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 55730 / SD2112.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002844 Genomic DNA. Translation: AEI57644.1.
RefSeq	YP_004649934.1. NC_015697.1.
3D structure databases
ProteinModelPortal	F8DL25.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEI57644; AEI57644; HMPREF0538_21434.
GeneID	10867488.
KEGG	lru:HMPREF0538_21434.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
BioCyc	LREU491077:GH1M-1544-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F8DL25_LACRS

Accession

Primary (citable) accession number: F8DL25

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)