Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F8DL25 (F8DL25_LACRS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2681Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1401Substrate By similarity HAMAP-Rule MF_01201
Binding site3151Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F8DL25 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 8C070DDEBC68098C

FASTA37541,270
        10         20         30         40         50         60 
MVNGRLRDTS LIVDLDALRH NIQEQRKVLP ENSRILAVVK ANAYGNGLIP VAQTAMTSGA 

        70         80         90        100        110        120 
SGLCVAILDE ALELWDNGIE AMTLVLGITP VEDALIAAQA GVSLTVGSLD WLEQYHQLAQ 

       130        140        150        160        170        180 
VAKPKKPLKV HLGIDSGMGR IGFTEVATFK QAVKLLDSPE FEFEGMFTHF ATADSPDENY 

       190        200        210        220        230        240 
FNQQVQRWHQ FVASLDELPP YVHMANSATG LWHREKITAN TVRMGISMYG QNPSGRDLKL 

       250        260        270        280        290        300 
TLDLQPVSSL VSSISFVKQL KAGRSVSYGA TYTAEQDEWL ATLPIGYADG YPRCMTGYKV 

       310        320        330        340        350        360 
LVDGQFCDIA GRVCMDQMMI QLPKYYPVGT PVVLMGKSGD QEITATDLAE QAGTINYEIL 

       370 
TNISNRVHRI YHQSK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002844 Genomic DNA. Translation: AEI57644.1.
RefSeqYP_004649934.1. NC_015697.1.

3D structure databases

ProteinModelPortalF8DL25.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEI57644; AEI57644; HMPREF0538_21434.
GeneID10867488.
KEGGlru:HMPREF0538_21434.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMAITMDQLM.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycLREU491077:GH1M-1490-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8DL25_LACRS
AccessionPrimary (citable) accession number: F8DL25
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)