Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei604 – 6041UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, LyaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSPAR760570:GI5E-881-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:HMPREF0833_10860Imported
OrganismiStreptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537)Imported
Taxonomic identifieri760570 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001502 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8DIV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLQKLENFR NKDIVKEEAE ILTDLLDDIT KNLVCPETFE KISQLKDLSK
60 70 80 90 100
TKNYRDLNQL VEQLSNEEMT VISRYFAILP LLINISEDVD LAYEINHLNN
110 120 130 140 150
VDGDYLGKLS STIKEVAKNE DAQEILENLN IVPVLTAHPT QVQRKTMLDL
160 170 180 190 200
TNHIHALLRQ HRDVKAGLIN ENKWYNNLRC NIEIMMQTDM IRDKKLKVTN
210 220 230 240 250
EITNVMEYYN SSFLQAVPNL VLEYKRLAKE HGLELEQPHP ITMGMWIGGD
260 270 280 290 300
RDGNPFVTAD TLKRSATIQS EVILNYYIEK ISKLYRHFSL STGLSNTSEA
310 320 330 340 350
VAEMAALSSD TSVFREKEPY RRAFHYIQSK LIQTLVNLKE WTMVGETRED
360 370 380 390 400
RYAVERLLGA SNHQQGPVSD YIGNRISGAL KEISAKESPA YASAQEFKED
410 420 430 440 450
LEKIKDSLLE NKSEYLISGE FAELLEAIDV FGFYLASIDM RQDSSVHEAC
460 470 480 490 500
VAELLKSAGI NDHYSDLSED KKCQILLKEL LEDPRILSAT HADKSELLEK
510 520 530 540 550
ELAIFQTARE LKDRLGEEVI RQNIISHATS VSDMLELAVM LKEVGLIDIE
560 570 580 590 600
KARVQIVPLF ETIEDLDHSE ETMRSYLSLP IAKRWIASKN NYQEIMLGYS
610 620 630 640 650
DSNKDGGYLS SCWTLFKAQQ QLTAIGDEFG VKITFFHGRG GTVGRGGGPT
660 670 680 690 700
YEAITSQPLK SINDRIRLTE QGEVIGNKYG NKDAAYYNLE MLVSATINRM
710 720 730 740 750
IAEQKSPFSM FDRFGEVMDK VVNRSYDIYR DLVFGNEHFY DYFFESSPIK
760 770 780 790 800
AISSFNIGSR PAARKTITEI GGLRAIPWVF SWSQSRVMFP GWYGVGSSFK
810 820 830 840 850
EFIDEDPENI ETLRYMYKNW PFFQSLLSNV DMVLSKANMD IAFEYAQLCE
860 870 880 890 900
EEEVRNIYQI ILHEWQLTKD IILMIEEQDE LLAENPYLKE SLDYRMPYFN
910 920 930 940
VLNYIQLELI RRQRTGQLPA DQDKLIHITI NGVATGLRNS G
Length:941
Mass (Da):107,888
Last modified:September 21, 2011 - v1
Checksum:iB0C5309EF0EA20E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002843 Genomic DNA. Translation: AEH55891.1.
RefSeqiWP_013903873.1. NC_015678.1.
YP_004621819.1. NC_015678.1.

Genome annotation databases

EnsemblBacteriaiAEH55891; AEH55891; HMPREF0833_10860.
GeneIDi10835359.
KEGGiscp:HMPREF0833_10860.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002843 Genomic DNA. Translation: AEH55891.1.
RefSeqiWP_013903873.1. NC_015678.1.
YP_004621819.1. NC_015678.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEH55891; AEH55891; HMPREF0833_10860.
GeneIDi10835359.
KEGGiscp:HMPREF0833_10860.

Phylogenomic databases

KOiK01595.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciSPAR760570:GI5E-881-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Streptococcus parasanguinis strain ATCC 15912."
    Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A., Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X., Perez L., Shen H., Wang Q., Watt J.
    , Xi L., Xin Y., Zhou J., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A., Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B., Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.
    Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537Imported.

Entry informationi

Entry nameiF8DIV6_STREP
AccessioniPrimary (citable) accession number: F8DIV6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 27, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.