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F8DGC5

- F8DGC5_STREP

UniProt

F8DGC5 - F8DGC5_STREP

Protein

Indole-3-glycerol phosphate synthase

Gene

trpC

Organism
Streptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotationSAAS annotation, Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesisUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSPAR760570:GI5E-1630-MONOMER.
    UniPathwayiUPA00035; UER00043.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Indole-3-glycerol phosphate synthaseUniRule annotation (EC:4.1.1.48UniRule annotation)
    Short name:
    IGPSUniRule annotation
    Gene namesi
    Name:trpCUniRule annotationImported
    Ordered Locus Names:HMPREF0833_11577Imported
    OrganismiStreptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537)Imported
    Taxonomic identifieri760570 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001502: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliF8DGC5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpC family.UniRule annotation

    Phylogenomic databases

    KOiK01609.
    OrthoDBiEOG6WT8JX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00134_B. IGPS_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00218. IGPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    PROSITEiPS00614. IGPS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F8DGC5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQEFLPKIL KEKAREVAEM KEEELQPLRE TYRLYDYLKS HPEKLQVIAE    50
    VKKASPSLGD IHVDVDIVAQ AKTYEENGAV MISVLTDEVF FKGSIEYLRE 100
    ISSQVRIPTL NKDFIVDEKQ VIRARNAGAT VILLIVAALS ETRLQELYEF 150
    ATHLGLEVLV ETHNLTELEV AHRIGAQIIG VNNRNLVTFE TDLHTSLELA 200
    TNFEQEPVYI SESAIFAAAD ARMLAPYFSG ILVGTALMKA DNVAEKVKEL 250
    QIDKG 255
    Length:255
    Mass (Da):28,630
    Last modified:September 21, 2011 - v1
    Checksum:i244F8C3C2EC9325E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002843 Genomic DNA. Translation: AEH56608.1.
    RefSeqiYP_004622536.1. NC_015678.1.

    Genome annotation databases

    EnsemblBacteriaiAEH56608; AEH56608; HMPREF0833_11577.
    GeneIDi10836108.
    KEGGiscp:HMPREF0833_11577.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002843 Genomic DNA. Translation: AEH56608.1 .
    RefSeqi YP_004622536.1. NC_015678.1.

    3D structure databases

    ProteinModelPortali F8DGC5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEH56608 ; AEH56608 ; HMPREF0833_11577 .
    GeneIDi 10836108.
    KEGGi scp:HMPREF0833_11577.

    Phylogenomic databases

    KOi K01609.
    OrthoDBi EOG6WT8JX.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00043 .
    BioCyci SPAR760570:GI5E-1630-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00134_B. IGPS_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00218. IGPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    PROSITEi PS00614. IGPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Streptococcus parasanguinis strain ATCC 15912."
      Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A., Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X., Perez L., Shen H., Wang Q., Watt J.
      , Xi L., Xin Y., Zhou J., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A., Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B., Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.
      Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537Imported.

    Entry informationi

    Entry nameiF8DGC5_STREP
    AccessioniPrimary (citable) accession number: F8DGC5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3