Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F8D907 (F8D907_HALXS) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617 HAMAP-Rule MF_00407

EC=6.5.1.1 RuleBase RU000617 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Halxa_2706 EMBL AEH37323.1
OrganismHalopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) [Complete proteome] [HAMAP] EMBL AEH37323.1
Taxonomic identifier797210 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalopiger

Protein attributes

Sequence length566 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617 HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2551N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2531ATP By similarity HAMAP-Rule MF_00407
Binding site2601ATP By similarity HAMAP-Rule MF_00407
Binding site2771ATP By similarity HAMAP-Rule MF_00407
Binding site3061ATP By similarity HAMAP-Rule MF_00407
Binding site3461ATP By similarity HAMAP-Rule MF_00407
Binding site4321ATP By similarity HAMAP-Rule MF_00407
Binding site4381ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
F8D907 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 16B23246232B88E2

FASTA56662,193
        10         20         30         40         50         60 
MQFATFADRA AAIEAEPADL EIVAHVTDLL RDAEADLEIV ARFVQGRVFP AWDSTTLDIG 

        70         80         90        100        110        120 
PSACYEAIAR AAGTNVDADD VEDRLAETGE IGDVAASYDF GGQQGLGAFT GGDGGEDDLT 

       130        140        150        160        170        180 
VREVYETLCD LAAAEGSGSQ DRKVDLLFGL FNRCSSEEAR YLARLVLSEM RIGVGEGAVR 

       190        200        210        220        230        240 
DAVAEAFDVP EEEVERALQV SNDYGEVARI ARDEGLEGLE AIDLEIGRPV QTMLAQAGTV 

       250        260        270        280        290        300 
TDALEEWDEA AVEWKYDGAR IQLHHAPDDD TTRVFSRNME EVTDALPEVL EYADETLEEP 

       310        320        330        340        350        360 
VILDGEVVAV DDDGGPLPFQ EVLKRFRRKH DVEKAREEVT VRPVFFDCLH AGGEDLLEEP 

       370        380        390        400        410        420 
LTARHDRLRA VLAEDPDAVT ETEDERDVEG LSLLWTTDDP DEIEAIDADA LEAGHEGIML 

       430        440        450        460        470        480 
KNPESTYSPG RRGKHWRKRK PDVETVDCVV TGAEWGEGRR ANFLGTFELS VRDGDDLETV 

       490        500        510        520        530        540 
GKVATGITDE KLEELTELLE PHIAAEDGQD VDLEPAVVFE VGYEEIQTSP TYSSGYALRF 

       550        560 
PRFLAVRSDK EPEDADTLER VEALRS 

« Hide

References

[1]"Complete genome sequence of Halopiger xanaduensis type strain (SH-6(T))."
Anderson I., Tindall B.J., Rohde M., Lucas S., Han J., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L., Pati A., Mikhailova N., Pagani I., Teshima H., Han C., Tapia R., Land M., Woyke T. expand/collapse author list , Klenk H.P., Kyrpides N., Ivanova N.
Stand. Genomic Sci. 6:31-42(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 18323 / JCM 14033 / SH-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002839 Genomic DNA. Translation: AEH37323.1.
RefSeqYP_004597202.1. NC_015666.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH37323; AEH37323; Halxa_2706.
GeneID10797660.
KEGGhxa:Halxa_2706.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.
OMAARVQVHK.

Enzyme and pathway databases

BioCycHXAN797210:GIXL-2062-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8D907_HALXS
AccessionPrimary (citable) accession number: F8D907
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 11, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)