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F8D4K8 (F8D4K8_HALXS) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase 1 HAMAP-Rule MF_00421
EC=6.3.5.3 HAMAP-Rule MF_00421
Alternative name(s):
Phosphoribosylformylglycinamidine synthase I HAMAP-Rule MF_00421
Gene names
Name:purQ HAMAP-Rule MF_00421
Ordered Locus Names:Halxa_1705 EMBL AEH36336.1
OrganismHalopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) [Complete proteome] [HAMAP] EMBL AEH36336.1
Taxonomic identifier797210 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halopiger ›

Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP-Rule MF_00421

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP-Rule MF_00421

Subunit structure

Heterodimer of two subunits, PurQ and PurL By similarity. HAMAP-Rule MF_00421

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00421.

Sequence similarities

Contains 1 glutamine amidotransferase type-1 domain. HAMAP-Rule MF_00421

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain2 – 229228Glutamine amidotransferase type-1 By similarity HAMAP-Rule MF_00421

Sites

Active site851Nucleophile By similarity HAMAP-Rule MF_00421
Active site2021 By similarity HAMAP-Rule MF_00421
Active site2041 By similarity HAMAP-Rule MF_00421

Sequences

Sequence LengthMass (Da)Tools
F8D4K8 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 6FA6AF2BCFCAE097

FASTA22924,712
        10         20         30         40         50         60 
MTVAIIRFGG SNCDRDAARA LEHLGIDAEI VWHEDGLPED TTGIVLPGGF SYGDYLRAGA 

        70         80         90        100        110        120 
MAARSPIVAE VREAASEGVP VLGVCNGAQI GCESGLTEGA FTTNESARFQ CEHVYLRVER 

       130        140        150        160        170        180 
DDTPWTAAYE EGEVIEVPIA HGEGRYEIRD ERLDELEEED RILFRYCDEN GETGPEVNPN 

       190        200        210        220 
GSKHNVAGVL GDRDTVAVLM PHPERATLPD VGPTDGQGVL RGFETGIDA

« Hide

References

[1]"Complete genome sequence of Halopiger xanaduensis type strain (SH-6(T))."
Anderson I., Tindall B.J., Rohde M., Lucas S., Han J., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L., Pati A., Mikhailova N., Pagani I., Teshima H., Han C., Tapia R., Land M., Woyke T. expand/collapse author list , Klenk H.P., Kyrpides N., Ivanova N.
Stand. Genomic Sci. 6:31-42(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 18323 / JCM 14033 / SH-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002839 Genomic DNA. Translation: AEH36336.1.
RefSeqYP_004596215.1. NC_015666.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH36336; AEH36336; Halxa_1705.
GeneID10796673.
KEGGhxa:Halxa_1705.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01952.
OMAFPGTNCD.

Enzyme and pathway databases

BioCycHXAN797210:GIXL-1043-MONOMER.
UniPathwayUPA00074; UER00128.

Family and domain databases

HAMAPMF_00421. PurQ.
InterProIPR017926. GATASE_1.
IPR010075. PRibForGlyAmidine_synth_I.
[Graphical view]
PIRSFPIRSF001586. FGAM_synth_I. 1 hit.
TIGRFAMsTIGR01737. FGAM_synth_I. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8D4K8_HALXS
AccessionPrimary (citable) accession number: F8D4K8
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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