F8D3P7 (F8D3P7_HALXS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	Halxa_2801 EMBL AEH37417.1

Organism

Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) [Complete proteome] [HAMAP] EMBL AEH37417.1

Taxonomic identifier

797210 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halopiger › Halopiger xanaduensis

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 EMBL AEH37417.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	10	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	F8D3P7 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: E8CC163A4C45EE0D	FASTA	177	19,931
	10 20 30 40 50 60 MERATFGGGC FWCVEAAFKE LEGVESVTSG YAGGHVENPT YEAVCRGETG HAEVVQLEYD 70 80 90 100 110 120 PDAVAYEDLL EVFFTIHDPT TKDREGPDVG SQYRSAIYAH DDDQLETAER FAEELENEGL 130 140 150 160 170 YEGIVTEIEP VEEFYEAEEY HQDYFEKNPN DAYCSMHAAP KVEKVREKFG DDVAATQ

References

[1]

"Complete genome sequence of Halopiger xanaduensis type strain (SH-6(T))." Anderson I., Tindall B.J., Rohde M., Lucas S., Han J., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L., Pati A., Mikhailova N., Pagani I., Teshima H., Han C., Tapia R., Land M., Woyke T. , Klenk H.P., Kyrpides N., Ivanova N. Stand. Genomic Sci. 6:31-42(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 18323 / JCM 14033 / SH-6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002839 Genomic DNA. Translation: AEH37417.1.
RefSeq	YP_004597296.1. NC_015666.1.
3D structure databases
ProteinModelPortal	F8D3P7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEH37417; AEH37417; Halxa_2801.
GeneID	10797754.
KEGG	hxa:Halxa_2801.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K07304.
OMA	QPFYPAE.
Enzyme and pathway databases
BioCyc	HXAN797210:GIXL-2157-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F8D3P7_HALXS

Accession

Primary (citable) accession number: F8D3P7

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)