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F8CX34 (F8CX34_GEOTC) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Geoth_0903 EMBL AEH46901.1
OrganismGeobacillus thermoglucosidasius (strain C56-YS93) [Complete proteome] [HAMAP] EMBL AEH46901.1
Taxonomic identifier634956 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
F8CX34 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 9A52A0F15EBF5BDD

FASTA42446,770
        10         20         30         40         50         60 
MVTQGEKITV TNGVLNVPNN PIIPFIEGDG TGPDIWAAAS RVLEAAVEKA YKGEKKIVWK 

        70         80         90        100        110        120 
EVLAGEKAYK QTGEWLPQET LDVIREYIIA IKGPLTTPVG GGIRSLNVAL RQELDLFVCL 

       130        140        150        160        170        180 
RPVRYFKGVP SPVKRPEDTD MVIFRENTED IYAGIEYAKG TPEVKKVIDF LQNEMGVRKI 

       190        200        210        220        230        240 
RFPETSGIGI KPISEQGTKR LVRAAIKYAI DHGRKSVTLV HKGNIMKFTE GAFKNWGYEL 

       250        260        270        280        290        300 
AEEEFSDKVF TWAQYDRIVE TEGKEAANKA LAEAEEAGKI IIKDVIADIF LQQILTRPRE 

       310        320        330        340        350        360 
FDVVATMNLN GDYISDALAA QVGGIGIAPG ANINYETGHA IFEATHGTAP KYAGLDKVNP 

       370        380        390        400        410        420 
SSVILSGVMM FEHLGWNEAA KLIVDALEKT IASKIVTYDF ARLMEGATEV KCSEFADAII 


RNME 

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References

[1]"Complete sequence of chromosome of Geobacillus thermoglucosidasius C56-YS93."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P. expand/collapse author list , Kourtz L., Mead D., Woyke T.
Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C56-YS93.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002835 Genomic DNA. Translation: AEH46901.1.
RefSeqYP_004586982.1. NC_015660.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH46901; AEH46901; Geoth_0903.
GeneID10787055.
KEGGgth:Geoth_0903.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycGTHE634956:GHH3-938-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8CX34_GEOTC
AccessionPrimary (citable) accession number: F8CX34
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 16, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)