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F8CU85 (F8CU85_GEOTC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2631Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1341Substrate By similarity HAMAP-Rule MF_01201
Binding site3101Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F8CU85 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 31A6DD05C4F17E4B

FASTA38143,277
        10         20         30         40         50         60 
MFYRDTWAEI DLDAIYYNVS QLKNFLPNDV RIMAVVKANA YGHGDVQVAK TALEAGASYL 

        70         80         90        100        110        120 
AVAFLDEALA LRKGGIDAPI LVLGASRPSD INIAAKHRIT LTVFQAEWIE QAADFYSETA 

       130        140        150        160        170        180 
PVLFHLKMDT GMGRLGVKEE TETKRLIEQI DRHPYFSLEG VYTHFATADE INTGYFSFQY 

       190        200        210        220        230        240 
DNFLRMLEWL PYKPPLIHCG NSATTLRFPD KVFNMVRFGI SMYGLSPSPE IKQYLPYTLK 

       250        260        270        280        290        300 
EAFSLHSRLV HVKKLKPGEK VSYGATYTAE TEQWVGTVPI GYADGWLRKL QNFHVLVNGE 

       310        320        330        340        350        360 
KAPIIGRICM DQLMVRLPKQ LPVGTKVTLI GRQGDKYISV DDVAQYLDTI NYEIPCTISY 

       370        380 
RVPRIFFRNK SIMEVRNLVY A 

« Hide

References

[1]"Complete sequence of chromosome of Geobacillus thermoglucosidasius C56-YS93."
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P. expand/collapse author list , Kourtz L., Mead D., Woyke T.
Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C56-YS93.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002835 Genomic DNA. Translation: AEH49527.1.
RefSeqYP_004589608.1. NC_015660.1.

3D structure databases

ProteinModelPortalF8CU85.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEH49527; AEH49527; Geoth_3701.
GeneID10789911.
KEGGgth:Geoth_3701.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycGTHE634956:GHH3-3793-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF8CU85_GEOTC
AccessionPrimary (citable) accession number: F8CU85
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)