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F8CDQ4

- F8CDQ4_MYXFH

UniProt

F8CDQ4 - F8CDQ4_MYXFH

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Protein

Thymidine kinase

Gene
tdk, LILAB_33315
Organism
Myxococcus fulvus (strain ATCC BAA-855 / HW-1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei73 – 731Proton acceptor By similarityUniRule annotation
Metal bindingi129 – 1291Zinc By similarityUniRule annotation
Metal bindingi132 – 1321Zinc By similarityUniRule annotation
Metal bindingi161 – 1611Zinc By similarityUniRule annotation
Metal bindingi164 – 1641Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi72 – 754ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMFUL483219:GJEO-6678-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:LILAB_33315Imported
OrganismiMyxococcus fulvus (strain ATCC BAA-855 / HW-1)Imported
Taxonomic identifieri483219 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus
ProteomesiUP000000488: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.
OMAiDHISEST.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F8CDQ4-1 [UniParc]FASTAAdd to Basket

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MFSGKTEELI RRVQRAVYGK QKVQVFKPRL DNRYDESAVV SHSQLKVMST    50
AIERAEEIFY RLAPDTQVVG IDEVQFFGSE VVAVVEALAN KGLRVICAGL 100
DQDYQGRPFE PMPQLMAVSE YVTKELAICV VCGNPANRSQ RIVSSGERVV 150
VGAAGAYEPR CRKCHVAEPA EGTPPQTLEL FD 182
Length:182
Mass (Da):20,178
Last modified:September 21, 2011 - v1
Checksum:i0D5185991CF0DAD9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002830 Genomic DNA. Translation: AEI68544.1.
RefSeqiWP_013941627.1. NC_015711.1.
YP_004669622.1. NC_015711.1.

Genome annotation databases

EnsemblBacteriaiAEI68544; AEI68544; LILAB_33315.
GeneIDi10881141.
KEGGimfu:LILAB_33315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002830 Genomic DNA. Translation: AEI68544.1 .
RefSeqi WP_013941627.1. NC_015711.1.
YP_004669622.1. NC_015711.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEI68544 ; AEI68544 ; LILAB_33315 .
GeneIDi 10881141.
KEGGi mfu:LILAB_33315.

Phylogenomic databases

KOi K00857.
OMAi DHISEST.

Enzyme and pathway databases

BioCyci MFUL483219:GJEO-6678-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-1."
    Li Z.F., Li X., Liu H., Liu X., Han K., Wu Z.H., Hu W., Li F.F., Li Y.Z.
    J. Bacteriol. 193:5015-5016(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-855 / HW-1.

Entry informationi

Entry nameiF8CDQ4_MYXFH
AccessioniPrimary (citable) accession number: F8CDQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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