F8C5Z2 (F8C5Z2_THESO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosome partition protein Smc HAMAP-Rule MF_01894

Gene names

Name:	smc HAMAP-Rule MF_01894
Ordered Locus Names:	TOPB45_1039 EMBL AEH23133.1

Organism

Thermodesulfobacterium sp. (strain OPB45) [Complete proteome] [HAMAP] EMBL AEH23133.1

Taxonomic identifier

795359 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermodesulfobacteria › Thermodesulfobacteria › Thermodesulfobacteriales › Thermodesulfobacteriaceae › Thermodesulfobacterium › Thermodesulfobacterium geofontis

Protein attributes

Sequence length	1138 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for chromosome condensation and partitioning By similarity. HAMAP-Rule MF_01894
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_01894
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01894.
Domain	Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures By similarity. HAMAP-Rule MF_01894
Sequence similarities	Belongs to the SMC family. HAMAP-Rule MF_01894

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_01894
Domain	Coiled coil HAMAP-Rule MF_01894
Ligand	ATP-binding HAMAP-Rule MF_01894 DNA-binding HAMAP-Rule MF_01894 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: InterPro DNA repair Inferred from electronic annotation. Source: InterPro DNA replication Inferred from electronic annotation. Source: HAMAP chromosome condensation Inferred from electronic annotation. Source: InterPro sister chromatid cohesion Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	32 – 39	8	ATP By similarity HAMAP-Rule MF_01894
	Coiled coil	168 – 503	336	By similarity HAMAP-Rule MF_01894
	Coiled coil	623 – 998	376	By similarity HAMAP-Rule MF_01894

Sequences

	Sequence		Length	Mass (Da)
	F8C5Z2 [UniParc]. Last modified September 21, 2011. Version 1. Checksum: 83A6846FA7484E93	FASTA	1,138	135,523
	10 20 30 40 50 60 MFIKRLEIYG FKSFPYKVSI PFSPKITAIV GPNGSGKSNI LDAIRWVLGE QSPKKLRVKE 70 80 90 100 110 120 LSDLIFSGNN NRNIDFAEVK LLLNHEPPVW ETYKDFPEIL ITRRFYRNGE SEYFINQKPC 130 140 150 160 170 180 RLKDIQFLFL DLGVNPQSYG IIEQGEVSKF IDLSPKERKI LLEDLAGVSK LKITEENTLK 190 200 210 220 230 240 NLQKTEENLL RLKDIINEVR GQYEILKKQA EEARKYISLK EKLQKLLIQK NLYLLELNQK 250 260 270 280 290 300 EKEKLKKRKE ELLNQKQTLE KEVECLEKEE QAIYQEILIL ERKIKDLKKD LQSKENYLKE 310 320 330 340 350 360 HKENLENLVK QENELNHKLE KIKLKRENEE EKFNNFNKEL STIEISLKNL REKKETLNEN 370 380 390 400 410 420 LINLKREKEK ISKIFEEKLK NFQNFEKEYL LTEKEEENLK EKRNSLEKKI SQLEKEKDIN 430 440 450 460 470 480 EKILEDLFIN LKNLEKEKKA LENLFKEKEK TLEDLINFKE KIIEDSKELY KKLENFNAKK 490 500 510 520 530 540 QNLLIEIQSL KDRLSLIEKI LSKNLSSISK NLNLPSLESY LNLSTEDISL LELIFKENLD 550 560 570 580 590 600 AFVIEELNLI KNFISQDLKE NIIFLWGEPE IIKSFSIERY NSFSDEILES YKTHPRFIYF 610 620 630 640 650 660 IKEKILLTPY GFICFIRKEK KGVFSLKKEK IDLLNKVEAL EKDLKTLLEK EKELKLKIEN 670 680 690 700 710 720 LEKELKRAEK EIKNINNGLE NLRSQKEKIE ISCIKLETEK INLGEKINHI ENELKSLKDE 730 740 750 760 770 780 KENLNKKLID ISELINRRKK EYETVKKENL SLKENLEEIN QKINFLEQEI IKIKTEEENL 790 800 810 820 830 840 RKRKDFIQEE IKKIKIFLRQ YEFDKEALLK EINYLKDKIK EFNKRIKNLS SEISDLTKVL 850 860 870 880 890 900 EDLLMKKEEG EKKLKALENK KRKIEKELKE LDTEEHNLEL YLLEKKLFLD SIYRNLKEFG 910 920 930 940 950 960 FEIETEFIQE NKEKFNLEEV EEEIEKTKNL LNEFKEVNLA SLREFEFVSQ RYEKLMKEKE 970 980 990 1000 1010 1020 DLEVSIREFK KILENIREIS RERILKTLEE VNKKLEEIFP LVFKNGKVEL LLSGEDPLSS 1030 1040 1050 1060 1070 1080 GLELKINFPH KGLKHINMLS GGEKSLCALV ILISFYLVKP GPFCILDEVD AFLDEKNSLK 1090 1100 1110 1120 1130 FIKLLDLIKR SSQIILITHN PHIMKEVDTL LGVTMEEKGI SKIFVIKKEN FFSEYINH

References

[1]

"Complete sequence of Thermodesulfobacterium sp. OPB45." Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hamilton-Brehm S., Elkins J., Woyke T. Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OPB45.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002829 Genomic DNA. Translation: AEH23133.1.
RefSeq	YP_004628061.1. NC_015682.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEH23133; AEH23133; TOPB45_1039.
GeneID	10839613.
KEGG	top:TOPB45_1039.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03529.
OMA	ERIRHAN.
Family and domain databases
HAMAP	MF_01894. Smc_prok.
InterPro	IPR003395. RecF/RecN/SMC. IPR024704. SMC. IPR011890. SMC_prok. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
PIRSF	PIRSF005719. SMC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F8C5Z2_THESO

Accession

Primary (citable) accession number: F8C5Z2

Entry history

Integrated into UniProtKB/TrEMBL:	September 21, 2011
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)