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F8BF63

- F8BF63_LISMM

UniProt

F8BF63 - F8BF63_LISMM

Protein

Ribonucleoside-diphosphate reductase subunit beta

Gene

nrdF

Organism
Listeria monocytogenes serotype 4a (strain M7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

    Catalytic activityi

    2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

    Cofactori

    Binds 2 iron ions per subunit.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Source: UniProtKB-EC

    GO - Biological processi

    1. deoxyribonucleoside diphosphate metabolic process Source: InterPro
    2. deoxyribonucleotide biosynthetic process Source: InterPro
    3. DNA replication Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    DNA replicationUniRule annotation

    Keywords - Ligandi

    IronUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciLMON1030009:GLFW-2312-MONOMER.
    UniPathwayiUPA00326.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonucleoside-diphosphate reductase subunit betaUniRule annotation (EC:1.17.4.1UniRule annotation)
    Gene namesi
    Name:nrdFImported
    Ordered Locus Names:LMM7_2256Imported
    OrganismiListeria monocytogenes serotype 4a (strain M7)Imported
    Taxonomic identifieri1030009 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
    ProteomesiUP000000486: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribonucleoside-diphosphate reductase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliF8BF63.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribonucleoside diphosphate reductase small chain family.UniRule annotation

    Phylogenomic databases

    KOiK00526.

    Family and domain databases

    Gene3Di1.10.620.20. 1 hit.
    InterProiIPR009078. Ferritin-like_SF.
    IPR012348. RNR-rel.
    IPR026023. RNR_bsu_prok.
    IPR000358. RNR_small.
    [Graphical view]
    PANTHERiPTHR23409. PTHR23409. 1 hit.
    PfamiPF00268. Ribonuc_red_sm. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000355. NrdB. 1 hit.
    SUPFAMiSSF47240. SSF47240. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F8BF63-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANQKEQLTR IKILEPLFPN RSTSIINGET SGILNWNDIP YPSFYRAYKE    50
    LSTNYWIPDE VDMKSDAKQY PALSEQEKYA FDAIIGLLAT LDSPQTRFIY 100
    NIAEYITDPA VHANAAIIAQ QEVIHNESYS YVLASITNLQ EQNRVFELAR 150
    THPTIIKRNE PIMDAYDDFM NNKTGETLVK ALIQSSILEG INFYSGFAYF 200
    YNLVRQNKMT GTGKIISFIN RDELAHSKFI SEVIRAILGE NPELQTEELV 250
    EYTHEAFRHA VELETEWSEE VLQGIEGIDV EEMVDYVKYR ANKMLGMLGI 300
    PELYPGHSDN TMTWIKAYAD NFTETKTDFF EMRNSSYKKT NMDNGFDDL 349
    Length:349
    Mass (Da):40,217
    Last modified:September 21, 2011 - v1
    Checksum:iD2F7BAD346A973E1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002816 Genomic DNA. Translation: AEH93261.1.
    RefSeqiYP_005948319.1. NC_017537.1.

    Genome annotation databases

    EnsemblBacteriaiAEH93261; AEH93261; LMM7_2256.
    GeneIDi12539079.
    KEGGilmq:LMM7_2256.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002816 Genomic DNA. Translation: AEH93261.1 .
    RefSeqi YP_005948319.1. NC_017537.1.

    3D structure databases

    ProteinModelPortali F8BF63.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEH93261 ; AEH93261 ; LMM7_2256 .
    GeneIDi 12539079.
    KEGGi lmq:LMM7_2256.

    Phylogenomic databases

    KOi K00526.

    Enzyme and pathway databases

    UniPathwayi UPA00326 .
    BioCyci LMON1030009:GLFW-2312-MONOMER.

    Family and domain databases

    Gene3Di 1.10.620.20. 1 hit.
    InterProi IPR009078. Ferritin-like_SF.
    IPR012348. RNR-rel.
    IPR026023. RNR_bsu_prok.
    IPR000358. RNR_small.
    [Graphical view ]
    PANTHERi PTHR23409. PTHR23409. 1 hit.
    Pfami PF00268. Ribonuc_red_sm. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000355. NrdB. 1 hit.
    SUPFAMi SSF47240. SSF47240. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nonpathogenic Listeria monocytogenes serovar 4a strain M7."
      Chen J., Xia Y., Cheng C., Fang C., Shan Y., Jin G., Fang W.
      J. Bacteriol. 193:5019-5020(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M7Imported.

    Entry informationi

    Entry nameiF8BF63_LISMM
    AccessioniPrimary (citable) accession number: F8BF63
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3