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F8BF63

- F8BF63_LISMM

UniProt

F8BF63 - F8BF63_LISMM

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Protein

Ribonucleoside-diphosphate reductase subunit beta

Gene

nrdF

Organism
Listeria monocytogenes serotype 4a (strain M7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Cofactori

Note: Binds 2 iron ions per subunit.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Source: UniProtKB-EC

GO - Biological processi

  1. deoxyribonucleoside diphosphate metabolic process Source: InterPro
  2. deoxyribonucleotide biosynthetic process Source: InterPro
  3. DNA replication Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

DNA replicationUniRule annotation

Keywords - Ligandi

IronUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciLMON1030009:GLFW-2312-MONOMER.
UniPathwayiUPA00326.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductase subunit betaUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
Name:nrdFImported
Ordered Locus Names:LMM7_2256Imported
OrganismiListeria monocytogenes serotype 4a (strain M7)Imported
Taxonomic identifieri1030009 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000000486: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribonucleoside-diphosphate reductase complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliF8BF63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase small chain family.UniRule annotation

Phylogenomic databases

KOiK00526.

Family and domain databases

Gene3Di1.10.620.20. 1 hit.
InterProiIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERiPTHR23409. PTHR23409. 1 hit.
PfamiPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFiPIRSF000355. NrdB. 1 hit.
SUPFAMiSSF47240. SSF47240. 1 hit.

Sequencei

Sequence statusi: Complete.

F8BF63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MANQKEQLTR IKILEPLFPN RSTSIINGET SGILNWNDIP YPSFYRAYKE
60 70 80 90 100
LSTNYWIPDE VDMKSDAKQY PALSEQEKYA FDAIIGLLAT LDSPQTRFIY
110 120 130 140 150
NIAEYITDPA VHANAAIIAQ QEVIHNESYS YVLASITNLQ EQNRVFELAR
160 170 180 190 200
THPTIIKRNE PIMDAYDDFM NNKTGETLVK ALIQSSILEG INFYSGFAYF
210 220 230 240 250
YNLVRQNKMT GTGKIISFIN RDELAHSKFI SEVIRAILGE NPELQTEELV
260 270 280 290 300
EYTHEAFRHA VELETEWSEE VLQGIEGIDV EEMVDYVKYR ANKMLGMLGI
310 320 330 340
PELYPGHSDN TMTWIKAYAD NFTETKTDFF EMRNSSYKKT NMDNGFDDL
Length:349
Mass (Da):40,217
Last modified:September 21, 2011 - v1
Checksum:iD2F7BAD346A973E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002816 Genomic DNA. Translation: AEH93261.1.
RefSeqiYP_005948319.1. NC_017537.1.

Genome annotation databases

EnsemblBacteriaiAEH93261; AEH93261; LMM7_2256.
GeneIDi12539079.
KEGGilmq:LMM7_2256.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002816 Genomic DNA. Translation: AEH93261.1 .
RefSeqi YP_005948319.1. NC_017537.1.

3D structure databases

ProteinModelPortali F8BF63.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEH93261 ; AEH93261 ; LMM7_2256 .
GeneIDi 12539079.
KEGGi lmq:LMM7_2256.

Phylogenomic databases

KOi K00526.

Enzyme and pathway databases

UniPathwayi UPA00326 .
BioCyci LMON1030009:GLFW-2312-MONOMER.

Family and domain databases

Gene3Di 1.10.620.20. 1 hit.
InterProi IPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view ]
PANTHERi PTHR23409. PTHR23409. 1 hit.
Pfami PF00268. Ribonuc_red_sm. 1 hit.
[Graphical view ]
PIRSFi PIRSF000355. NrdB. 1 hit.
SUPFAMi SSF47240. SSF47240. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nonpathogenic Listeria monocytogenes serovar 4a strain M7."
    Chen J., Xia Y., Cheng C., Fang C., Shan Y., Jin G., Fang W.
    J. Bacteriol. 193:5019-5020(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M7Imported.

Entry informationi

Entry nameiF8BF63_LISMM
AccessioniPrimary (citable) accession number: F8BF63
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 26, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3