Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F8BB62

- F8BB62_LISMM

UniProt

F8BB62 - F8BB62_LISMM

Protein

Isocitrate dehydrogenase [NADP]

Gene

citC

Organism
Listeria monocytogenes serotype 4a (strain M7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciLMON1030009:GLFW-1674-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:citCImported
    Ordered Locus Names:LMM7_1652Imported
    OrganismiListeria monocytogenes serotype 4a (strain M7)Imported
    Taxonomic identifieri1030009 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
    ProteomesiUP000000486: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F8BB62-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQKIQVENG VLKTPNNPVI PFIEGDGTGP DIWAAAKRVL DAAVKKAYNG    50
    EKEIAWKEVL AGEKAFKQTG EWLPQATLDT IDEYLIAIKG PLTTPIGGGI 100
    RSLNVALRQE LDLYVCLRPV RYFKGVPSPV KRPEDTDMVI FRENTEDIYA 150
    GIEFKEGSVE SKKLIDFLKS EFGVDKIRFP ETSGIGIKPI SKEGTERLVR 200
    SAIEYTIKEG RKSLTLVHKG NIMKFTEGAF KNWGYDLCER EYGDKVFTWN 250
    EYDRIKEAEG TEVADAKQKE ALAAGKILVK DSIADIFLQQ ILTRPAEFDV 300
    VATMNLNGDY ISDALAAQVG GIGIAPGANI NYLTGHAIFE ATHGTAPKYA 350
    GLDKVNPSSV ILSGTLLLEH IGWGEAAALI NQSMEKTIAA KTVTYDFARL 400
    MDGATEVKCS EFADELIKNF 420
    Length:420
    Mass (Da):46,178
    Last modified:September 21, 2011 - v1
    Checksum:i46CF5C8D72C65F4B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002816 Genomic DNA. Translation: AEH92657.1.
    RefSeqiWP_012581261.1. NC_017537.1.
    YP_005947715.1. NC_017537.1.

    Genome annotation databases

    EnsemblBacteriaiAEH92657; AEH92657; LMM7_1652.
    GeneIDi12538441.
    KEGGilmq:LMM7_1652.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002816 Genomic DNA. Translation: AEH92657.1 .
    RefSeqi WP_012581261.1. NC_017537.1.
    YP_005947715.1. NC_017537.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEH92657 ; AEH92657 ; LMM7_1652 .
    GeneIDi 12538441.
    KEGGi lmq:LMM7_1652.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci LMON1030009:GLFW-1674-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nonpathogenic Listeria monocytogenes serovar 4a strain M7."
      Chen J., Xia Y., Cheng C., Fang C., Shan Y., Jin G., Fang W.
      J. Bacteriol. 193:5019-5020(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M7Imported.

    Entry informationi

    Entry nameiF8BB62_LISMM
    AccessioniPrimary (citable) accession number: F8BB62
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3