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F8AUZ4

- F8AUZ4_FRADG

UniProt

F8AUZ4 - F8AUZ4_FRADG

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Protein
Alanine racemase
Gene
FsymDg_3922
Organism
Frankia symbiont subsp. Datisca glomerata
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei40 – 401Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei138 – 1381Substrate By similarityUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciFSYM656024:GHLT-3953-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:FsymDg_3922Imported
OrganismiFrankia symbiont subsp. Datisca glomerataImported
Taxonomic identifieri656024 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
ProteomesiUP000001549: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei40 – 401N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF8AUZ4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.
OMAiIYSHLAL.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8AUZ4-1 [UniParc]FASTAAdd to Basket

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MTTQSEGLRA CAIVDLDAVR ASVATLVARA GNAATMAVVK SDGYGHGMSA    50
CARAAVEAGA SWLGVAVIEE GLALRAAGFT VPVFAWLTAP GEPLADALAA 100
DIDLSASAPW MLAEIAAAAR HTGRRARVHL KADTGLGRGG ATEADWPSLC 150
DAAAALAAED LIEVTGVWSH LAFADSPGHP TVRGQIGRFA DAVTIAEKTG 200
LRPQVRHLAN SAATLVSPDA RFDMVRPGIS VYGLSPGPQV GSPAALGLRP 250
AMTLTARLAL AKRVPAGSGV SYAHRYTTAV ASTLGLVPLG YADGVPRAAG 300
NTAEVLLAGR RRRIAGTVCM DQFVVDVGDD PVQAGDQVIL FGSGEHGEPT 350
AQDWADALGT INYEIVTRVG VRVPRVHLNA SDGPRGTGRQ APGGPGAARP 400
APGMAGSAPA AVGPSDAGLS GAGSSGPGLP GAGPSAPGWL PS 442
Length:442
Mass (Da):44,366
Last modified:September 21, 2011 - v1
Checksum:i2919D5013DA8C90F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002801 Genomic DNA. Translation: AEH11197.1.
RefSeqiWP_013875075.1. NC_015656.1.
YP_004585118.1. NC_015656.1.

Genome annotation databases

EnsemblBacteriaiAEH11197; AEH11197; FsymDg_3922.
GeneIDi10784610.
KEGGifsy:FsymDg_3922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002801 Genomic DNA. Translation: AEH11197.1 .
RefSeqi WP_013875075.1. NC_015656.1.
YP_004585118.1. NC_015656.1.

3D structure databases

ProteinModelPortali F8AUZ4.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEH11197 ; AEH11197 ; FsymDg_3922 .
GeneIDi 10784610.
KEGGi fsy:FsymDg_3922.

Phylogenomic databases

KOi K01775.
OMAi IYSHLAL.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci FSYM656024:GHLT-3953-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Frankia symbiont of Datisca glomerata."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O., Teshima H., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Berry A.
    , Pawlowski K., Persson T., Vanden Heuvel B., Benson D., Woyke T.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 4085684Imported.

Entry informationi

Entry nameiF8AUZ4_FRADG
AccessioniPrimary (citable) accession number: F8AUZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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